Awards for April 2017

Federal Awards

Bai, Xiaoying, NIH, Role of Transcription Pausing in Hematopoietic Stem Cell Development, $318,736; Berglund, Eric, NIH, Novel Insulin-Independent Gluco-Regulatory Mechanisms, $328,050; Burstein, Ezra, NIH, Role of the CCC Complex in Immune Function, $364,500; Castrillon, Diego, NIH, Novel Tumorigenic Mechanisms of the LKB1 Tumor Suppressor, $333,517; Chen, David, Univ of California, Berkeley/NIH, Structural Cell Biology of DNA Repair Machines, $21,870; Chen, Elizabeth, NIH, Dissecting the Mechanisms of Cell-Cell Fusion Using a Cell Culture System, $298,890; Chen, Elizabeth, NIH, Molecular Mechanisms of Myoblast Fusion, $79,793; Chen, Zhijian, Baylor Scott & White/NIH, Measure cGAMP Levels in the Peripheral Blood Mononuclear Cells of SLE Patients, $83,592; Diamond, Marc, Dept of Defense, Development of In Vivo Biomarkers, $286,643;

Garcia, Joseph, NIH, Mechanistic Studies and Translational Applications of Stress Signaling in Anemia, $405,000; Gupta, Rana, NIH, Establishment and Maintenance of Healthy Adipose Tissue in Obesity, $328,050; Halm, Ethan, N California Inst/NIH, Comparative Effectiveness of Carotid Artery Revascularization, $30,088; Hibbs, Ryan, NIH, Structural Biology of the alpha4beta2 Nicotinic Acetylcholine Receptor, $400,891; Hilgemann, Donald, NIH, Palmitoylation-Dependent Massive Endocytosis (pMEND), $397,500; Hill, Joseph, NIH, Mechanisms of Obesity-Dependent Alterations in Cardiomyocyte Metabolism, $405,000; Jia, Xun, NIH, Explore Random Sampling for Dose Reduction and Scatter Removal in Cone Beam CT, $216,334; Johnson, Jane, NIH, Transcription Factor Control of Neuronal Diversity, $445,409; Kennard, Beth, Johns Hopkins Univ/NIH, LOC-IMPACT Leadership Group, $17,992;

Kramer, Helmut, NIH, Endocytic Trafficking and Cell Signaling in Models of ARC Syndrome, $332,100; Levine, Benjamin, Univ of Washington/NASA, Invasive and Noninvasive ICP Monitoring and VIIP Biomarker Identification, $14,802; Lin, Rueyling, NIH, Reprogramming by mRNA Clearance: The MAT-to-ZYG Transition, $353,430; Liu, Yi, NIH, Mechanisms of Circadian Clock and Gene Silencing in Neurospora, $546,751; Macdonald, Raymond, NIH, Transcriptional Regulators of the Exocrine Pancreatic Phenotype, $426,364; Makam, Anil, NIH, Post-Acute Care in the Elderly: the Role of Long-Term Acute Care Hospitals, $185,760; Marciano, Denise, NIH, Role of Afadin Signaling in Nephron Tubulogenesis, $311,242; Mattrey, Robert, Thomas Jefferson Univ/NIH, 2D and 3D Contrast-enhanced Ultrasound Evaluation of HCC Chemoembolization, $29,251; McClintock, Shawn, Univ of New Mexico/NIH, ECT Pulse Amplitude and Medial Temporal Lobe Engagement, $8,613;

Monteggia, Lisa, NIH, Antidepressants & Intracellular Signaling Linked to BDNF, $499,712; Mootha, Venkateswara, NIH, Genetics & Genomics of Fuchs Endothelial Corneal Dystrophy, $364,500; Nam, Yunsun, NIH, Mechanisms of Microprocessor Function and Regulation, $333,479; Pan, Duojia, Johns Hopkins Univ/Dept of Defense, Developing Molecular Targeted Therapies Against NF2, $177,806; Patrie, Steven, NIH, Algorithms for Glyco-Proteoform Detection, $328,050; Paulk, Mary, Weill Cornell Medical College/NIH, Latino vs. Non-Latino Disparities in Advance Care Planning & End-of-Life Care, $20,591; Phelps, Katherine, NIH, TEM for UT Southwestern Electron Microscopy Core Facility, $397,990; Robertson, Danielle, NIH, Effects of Systemic Disease on Corneal Epithelial Pathophysiology, $364,500; Rohatgi, Anand, NIH, Moving Beyond HDL Cholesterol, HDL Function as a Coronary Disease Biomarker, $155,725;

Ross, Theodora, NIH, The Roles and Regulation of BRCA1 in Hematopoiesis, $405,000; Sadek, Hesham, NIH, Regulation of Cardiomyocyte Turnover in the Adult Mammalian Heart, $405,000; Sarma, Satyam, UT Arlington/NIH, Mechanisms and Management of Exercise Intolerance in Older Heart Failure Patients, $12,285; Skapek, Stephen, NIH, Tgf Beta 2 Controls p19Arf During Eye Development, $357,750; Strand, Douglas, NIH, Interplay Between Stem Cells and Inflammation in Benign Prostatic Hyperplasia, $72,900; Tambar, Uttam, NIH, Stereoselective Rearrangements for the Synthesis of Bioactive Small Molecules, $324,000;

Tamminga, Carol, NIH, 1/5 Bipolar-Schizophrenia Network for Intermediate Phenotypes 2 (B-SNIP 2), $645,384; Tamminga, Carol, Mt Sinai School of Medicine/NIH, Epigenetic Mechanisms of Depression, $166,949; Thomas, Philip, NIH, Development of Membrane Protein Structure, $327,840; Tiro, Jasmin, Venturewell/NIH, Self-Persuasion, $21,750; Weakley, David, Emory Univ/NIH, Infant Aphakia Treatment Study, $12,092; Winter, Sebastian, NIH, Central Metabolism of Salmonella in the Inflamed Gut, $405,000; Wyckoff, Myra, NIH, NICHD Cooperative Multicenter Neonatal Research Network, $275,338; Xie, Yang, NIH, Integrative Analysis to Identify Regulation Targets of RNA-Binding Proteins, $291,600.

Nonfederal Awards

Argenbright, Keith, CPRIT, Population Based Screening for Hereditary Breast and Ovarian Cancer, $500,946; Argenbright, Keith, CPRIT, XSPAN: Cervical Screening and Patient Navigation, $495,945; Butts, Ryan, Amer Heart Assoc, Effect of Carvedilol on Exercise Performance in Fontan Patients, $57,750; Chook, Yuh Min, Welch Fdn, Mechanisms of Importin 8-mediated Nuclear Import, $80,000; Cobb, Melanie, CPRIT, Dependence of Small Cell Lung Cancer on the Basic Helix-Loop-Helix Transcription, $300,000; Cobb, Melanie, Welch Fdn, Regulatory and Catalytic Properties of MAP Kinase Cascades, $80,000; Conacci-Sorrell, Maralice, Welch Fdn, Non-Canonical Functions of Myc in Protein Acetylation and Chemoresistance, $65,000; Conrad, Nicholas, Welch Fdn, Biochemical Analysis of a Novel S-Adenosylmethionine Sensor, $65,000; Corbin, Ian, METAvivor Research, Lipoprotein Omega-3 Fatty Acid Nanoparticles: Novel Treatment for Breast Cancer, $40,000;

Corey, David, Welch Fdn, Recognition of Cellular Nucleic Acids by Synthetic Oligomers, $110,000; Danuser, Gaudenz, Welch Fdn, Probing Oncogenic Functions of Vimentin Filaments by Small Molecule Screens, $80,000; De Brabander, Jef, Welch Fdn, Synthesis and Chemical Biology of Bioactive Small Molecules, $80,000; Ding, Kan, Darrell K Royal Fund for Alzheimer’s Res, Neurovascular Decoupling and Cognitive Impairment in TBI, $55,000; Doncic, Andreas, Welch Fdn, Investigating Cell Fate Decisions During Yeast Sporulation Using Live Single Cell Metabolite Measurements, $65,000; Engelking, Luke, Gilead Sciences, Gilead Research Scholar Award, $65,000; Frederick, Kendra, Welch Fdn, Protein-Mediated Trans Splicing for Polymorphic Amyloid Structure Determination, $65,000; Goodman, Joel, Texas Workforce Comm, SCOPE: Science Concepts Promoted through Experimentation, $58,013; Hon, Gary (Fellow E. Stroebele), Welch Fdn, Epigenetic Control of Non-Coding Gene Regulation, $65,000; Jewell, Jenna, Welch Fdn, Deciphering the Glutamine Signaling Pathway to mTORC1, $65,000;

Kohler, Jennifer, Welch Fdn, Discovering the Glycoconjugate Receptors of Pertussis Toxin, $80,000; Kraus, William (Fellow Y. Vasquez), Lalor Fdn, Genetic Dissection of Estrogen-Regulated Enhancers in the Uterus, $49,999; Liu, Qinghua, Welch Fdn, Chemosensing Mechanism of Thiazoline Odor-Evoked Innate Fear, $65,000; Luo, Xuelian, Welch Fdn, Chemical Inhibition of the Hippo TEAD–YAP Transcription Factors for Cancer Therapy, $65,000; Mangelsdorf, David (Fellow S. Sun), Helen Hay Whitney Fdn, Identification of a Missing Molecular Link in Bile Acid Metabolism, $53,500; Nam, Yunsun, Welch Fdn, Structure and Function Relationship of microRNA Precursors, $60,000; Patrie, Steven, Texas A&M Univ/Texas Alzheimer’s Consort, Computational Tools for Molecular Proteotyping: A Unique Approach to Alzheimer's, $60,000; Ready, Joseph, Welch Fdn, New Directions in Asymmetric Synthesis, $80,000;

Rosen, Michael, Welch Fdn, 2D Phase Separated Protein Polymers: Interactions with Actin Filaments, $110,000; Rosenbaum, Daniel, Welch Fdn, Capturing the Active Conformations of CNS GPCRs with Nanobodies, $110,000; Shay, Jerry, Cystic Fibrosis Fdn, Genomic Editing of Normal and CF Human Lung Epithelial Cells, $108,000; Sher, David, UT MD Anderson/CPRIT, Comparative Effectiveness Research on Cancer in Texas (CERCIT), $37,797; Wang, Yingfei, Welch Fdn, Biochemical Characterization of PAAN, $65,000; Xu, Jian, Welch Fdn, In Situ Analysis of the Structure-Function of Transcriptional Enhancers, $65,000; Zhang, Xuewu, Welch Fdn, Structural and Functional Analyses of the BCCIPß/RPL23 Complex, $80,000; Zhong, Qing, Welch Fdn, Identification of Autophagy-Specific Factors for Autophagosome-Lysosome Fusion, $80,000. 

Industry Sponsored Awards, dollar amounts not available

Bird, John, DBV Technologies, Long-Term Study pf Viaskin Peanut (People Study); Collins, Robert, Celgene Corp, Phase 1b/2 Study of IDH Mutant Target Therapies plus Azacitidine for Acute Myeloid Leukemia; Courtney, Kevin, Stemline Therapeutics, Phase 1 Study of SL-801, a Reversible Inhibitor of Nuclear Export, for Advanced Solid Tumors; Cripps, Michael, Arsanis, Phase 2 Study of ASN100 for Prevention of Staphylococcus aureus Pneumonia in Mechanically Ventilated Subjects; Frankel, Arthur, Constellation Pharma, Phase 2 Study of CPI-0610, a Small Molecule Inhibitor of BET Proteins for Malignant Peripheral Nerve Sheath Tumors; Garg, Abhimanyu, Intercept Pharma, Phase 2 Study of Obeticholic Acid for Lipodystrophy; Hammers, Hans, Merck Sharp & Dohme, Phase 3 Study of Pembrolizumab (MK-3475) with Axitinib for Renal Cell Carcinoma; Jain, Mamta, Social & Scientific Systems, Phase 3 Study of High vs. Low Titer Anti-Influenza Immune Plasma for Severe Influenza A; Jha, Manish, Acadia Pharma, Phase 2 Study of Adjunctive Pimavanserin in Major Depressive Disorder;

 Khemani, Pravin, Biohaven Pharma, Phase 2b/3 Trial of BHV-4157 for Spinocerebellar Ataxia; Lee, William, Conatus Pharma, Trial of Emricasan, an Oral Caspase Inhibitor, for Non-Alcoholic Steatohepatitis (NASH) Cirrhosis and Severe Portal Hypertension; Lingvay, Ildiko, Novo Nordisk, Study of Semaglutide versus Canagliflozin as add-on to Metformin for Type 2 Diabetes; Lotan, Yair, MDxHealth, Prospective Validation of Prostate Biomarkers for Repeat Biopsy; Mayo, Marlyn, Cymabay Therapeutics, Phase 2 Study of MBX-8025 for Primary Biliary Cholangitis; Shah, Trushil, Bayer, International Study of Riociguat for Pulmonary Arterial Hypertension (PAH); Simms-Waldrip, Tiffany, Jazz Pharma, Defibrotide for Prevention of Hepatic Veno-Occlusive Disease in Patients Undergoing Hematopoietic Stem Cell Transplant; Thibodeau, Jennifer, Novartis, Study of Sacubitril and Valsartan for Acute Decompensated Heart Failure (ADHF); Yopp, Adam, Cryolife, Trial of PerClot Polysaccharide Hemostatic System.