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Newsroom Article Archive

Why the dose matters: Study shows that levels of drug in body correlate to ability to shrink tumors

 

When used to manage infections, the drug itraconazole is generally given at a single, fixed dose to all patients.

Factors inherent to obesity could increase vulnerability to COVID-19

 

Conditions related to obesity, including inflammation and leaky gut, leave the lungs of obese patients more susceptible to COVID-19 and may explain why they are more likely to die from the disease, UTSW scientists say in a new article published online in eLife.

UTSW pilots innovative tech to improve surgical skills, patient outcomes

 

For more than a century, hospitals have relied on traditional conferences, surgical meetings, and case reviews to identify opportunities to improve training, quality, and patient outcomes.

Generic cholesterol drugs save Medicare billions of dollars, study finds

 

The switch from brand name to generic cholesterol medications that occurred between 2014 and 2018 has saved Medicare billions of dollars, even as the number of people on cholesterol-lowering drugs has increased.

Dropping it in the mail: Best practices detailed for mail-in colon cancer screenings

 

A program that asks patients to mail in stool samples to screen for colon cancer is an effective way to expand screenings to underserved and underinsured communities and offers an alternative to in-person testing during the pandemic, according to a study conducted by UT Southwestern.

Researchers show how mutations in DNA packaging machines cause cancer

 

Like wrenches made of Legos, SWI/SNF chromatin remodeling complexes tighten or loosen DNA in our cells to control how genes are turned on and made into proteins.

Attacking tumors from the inside

 

A new technology that allows researchers to peer inside malignant tumors shows that two experimental drugs can normalize aberrant blood vessels, oxygenation, and other aspects of the tumor microenvironment in non-small cell lung cancer (NSCLC), helping to suppress the tumor’s growth and spread, UT Southwestern researchers report.

UTSW performs first HIV-positive-to-HIV-positive organ transplant in Texas

 

Less than three weeks after getting on an organ transplant list for HIV-positive patients, John Welch got the call. A liver was available from a deceased donor, and it was an excellent match.

Study details how general anesthetics and 'benzos' act on receptors in the brain

 

As you drift into unconsciousness before a surgery, general anesthetic drugs flowing through your blood are putting you to sleep by binding mainly to a protein in the brain called the ɣ-aminobutyric acid type A (GABAA) receptor.

Roger H. Unger, M.D., visionary endocrinologist and preeminent authority on diabetes: 1924-2020

 

Roger H. Unger, M.D., a longtime Professor of Internal Medicine, a preeminent authority on glucagon and the development of diabetes, and the founding Director of the Touchstone Center for Diabetes Research at UT Southwestern Medical Center, died Aug. 22. He was 96.