Federal, non-federal, and industry-sponsored grants awarded to UT Southwestern faculty in March 2016.

Federal Awards

Borek, Dominika, Georgia State Univ/NIH, Therapeutics Targeting Filoviral Interferon-Antagonist, $21,176; Brekken, Rolf (Fellow N. Sorrelle), NIH, Pleiotrophin Promotes a Pro-Tumor and Pro-Metastatic Phenotype, $31,448; Brugarolas, James, NIH, Evaluation of BAP1 Tumor Suppressor Gene in Renal Cell Carcinoma, $32,993; Burma, Sandeep, NASA, Mechanistic Analysis of Particle Radiation-Induced Carcinogenesis Using Validated Mouse Glioma Models, $120,246; Carroll, Thomas, NIH, Delineating a Role for Non-Canonical WNT Signaling in PKD, $345,825; Casey, Brian, NIH, Eunice Kennedy Shriver NICHD Maternal-Fetal Medicine Units (MFMU), $17,798; Castrillon, Diego, NIH, Novel Tumorigenic Mechanisms of the LKB1 Tumor Suppressor, $370,194;

Chen, Benjamin, NIH, DNA-PKcs Phosphorylation on Hematopoietic Stem Cells Genome Maintenance, $329,925; Chen, David, NIH, Pathway Choice of DNA Double-Strand Break Repair, $329,925; Chiang, Cheng-Ming, NIH, E2-Cellular Complexes in HPV Chromatin Transcription, $395,910; Chook, Yuh Min, NIH, Structures and Mechanisms of Nuclear Import and Export, $33,350; Corey, David, NIH, Mechanism of RNA-Mediated Control of Transcription of Splicing, $28,620; Cowell, Lindsay, NIH, RepServer: Antigen Receptor Repertoire Analysis Pipelines via the WWW, $598,306; Danuser, Gaudenz (Fellow E. Welf), NIH, Mechanisms of Melanoma Migration and Survival in 3D Microenvironments, $117,180;

Diamond, Marc, NIH, Development of Novel Therapeutic Anti-Tau Antibodies, $578,134; Diamond, Marc (Fellow J. Furman), NIH, Screening and Immunization: A Novel Approach to Tau Antibody Therapeutics, $58,002; Falck, J Russell, Vanderbilt Univ/NIH, Role of Icosanoids in Renal Function: Core C, $145,350; Garg, Abhimanyu, NIH, Genetic and Metabolic Basis of Familial Lipodystrophies, $560,975; Gerber, David, NIH, UT Southwestern NCI National Clinical Trials Network, $645,976; Graff, Jonathan (Fellow D. Berry), NIH, Regulators of the Adipose Tissue Niche Control Adiposity and Metabolism, $99,940;

Greenberg, David, NIH, Circumventing Antibiotic Resistance with Novel Gene-Silencing Therapeutics, $474,777; Greenberg, David, NIH, Gene Silencing Therapeutics for Chronic Infections in Cystic Fibrosis, $366,879; Gundert, Emily, Indiana Univ/NIH, Randomized Trial of Inhaled Nitric Oxide to Treat Acute Pulmonary Embolism, $53,999; Haley, Robert, Johns Hopkins Univ/Dept of Defense, Direct Test for Neuroinflammation with [11C]DPA-713-PET Scanning, $31,318; Henkemeyer, Mark, NIH, Bidirectional Tyrosine Kinase Signaling, $523,695; Hilgemann, Donald, NIH, Palmitoylation-Dependent Massive Endocytosis (pMEND), $397,500; Hooper, Lora, NIH, Integrative Immunology Training Program, $361,568;

Hsieh, Jenny, NIH, Targeting Aberrant Neurogenesis to Prevent Epilepsy and Associated Cognitive Decline, $353,919; Jain, Mamta, UNT HSC/NIH, Impact of HIV-1 Nef in Acceleration of HCV-Mediated Liver Disease, $33,883; Jiang, Jin, NIH, Mechanism of Hedgehog Signal Transduction Across the Plasma Membrane, $32,097; Journeycake, Janna, UTHSC Houston/CDC, CDC Community Counts Project, $21,756; Journeycake, Janna, Blood Center of Wisc/NH, Comparative Effectiveness in the Diagnosis of VWD, $2,250; Kennard, Beth, NIH, 2/2 Brief Intervention for Suicide Risk Reduction in High Risk Adolescents, $23,850;

Kliewer, Steven, NIH, Tissue-Specific Mechanism of Action of Metabolic Hormones FGF19 and FGF21, $347,853; Kowalske, Karen, UT Med Branch/Dept of Defense, Early Exercise in the Burn Intensive Care Unit, $66,209; Kutz, Joe, Duke Clinical Res Inst/NIH, CHEER Network: Creating Healthcare Excellence Through Education and Research, $5,000; Le, Lu Quang, NIH, Roles of Tumor Microenvironment in Neurofibroma Development and Therapeutics, $329,925; Le, Lu Quang, Dept of Defense, Parallels Between Nerve Scar Formation and Neurofibroma Development, $80,895; Li, Wen-Hong, VitalQuan/NIH, Fluorescent Probes for Tracking Insulin Secretion in Therapeutic and Diagnostic D, $3,230; Lin, Rueyling, NIH, Reprogramming by mRNA Clearance: The Maternal-to-Zygotic Transition, $392,259;

Lin, Weichun, NIH, Patterning and Formation of Neuromuscular Junction, $347,813; Liu, Qinghua, NIH, Molecular Mechanisms of the RNAi/MicroRNA Pathways, $339,675; Liu, Xin, NIH, Molecular Mechanisms of Promoter-Terminator Gene Looping, $308,188; Lum, Lawrence, NIH, Chemical Disruption of Wnt-Mediated Signal Transduction, $464,007; Lum, Lawrence, NIH, Targeting Vismodegib-resistant Tumors Using BH3 Mimetics, $346,539; Luo, Weibo, NIH, The Role of JMJD2C in HIF-1 Activation and Breast Cancer Progression, $24,901; Macdonald, Raymond, NIH, Transcriptional Regulators of the Exocrine Pancreatic Phenotype, $473,186;

Mahendroo, Mala, NIH, Mechanisms of Infection-Mediated Cervical Ripening, $419,398; Mahony, Lynn, New England Res Inst/NIH, Pediatric Heart Disease Research Protocol Chair, $67,499; Makam, Anil, NIH, Post-Acute Care in the Elderly: The Role of Long-Term Acute Care Hospitals, $152,820; Marciano, Denise, NIH, Role of Afadin Signaling in Nephron Tubulogenesis, $345,825; Minna, John (Fellow A. Augustyn), NIH, Defining Molecularly Distinct Subtype of Non Small Cell Lung Cancer, $37,476; Monteggia, Lisa, NIH, Antidepressants & Intracellular Signaling Linked to BDNF, $616,138; Moore, William, UT Dallas/NIH, Neuroimaging of Dedifferentiation and Memory Across the Lifespan, $17,293;

Pasare, Chandrashekhar, NIH, Role of Microenvironmental Cues in CD8 T Cell Activation and Memory Generation, $202,240; Patrie, Steven, NIH, Algorithms for Glyco-Proteoform Detection, $364,031; Pfeiffer, Julie, NIH, Genetics of Bacteria-Mediated Viral Co-Infection, $202,240; Powell, Craig, NIH, Novel Genetic Models of Autism, $625,949; Ready, Joseph, Mount Sinai School of Med/NIH, Therapeutics Targeting Filoviral Interferon-Antagonist and Replication Functions, $362,718; Ready, Joseph, NIH, Synthesis and Evaluation of Biologically Active Natural Products, $294,701; Reese, Michael, Natl Science Fdn, Career: Leveraging a Fast-Evolving Kinase Family to Gain Fundamental Understanding of Kinase Evolution, $218,394;

Rizo-Rey, Jose, NIH, Regulation of Neurotransmitter Release by C2-domain Proteins, $447,875; Rodriguez-Baez, Norberto, Johns Hopkins Univ/NIH, Immunologic and Virologic Correlates of the Age-Related Decrease in HBV DNA in Children, $46,842; Rosenberg, Roger, Columbia Univ/NIH, Epidemiology of Familial Late-Onset Alzheimer's Disease, $4,700; Rutherford, Cynthia, UTHSC Houston/CDC, CDC Community Counts Project, $18,336; Sadek, Hesham, NIH, Regulation of Cardiomyocyte Turnover in the Adult Mammalian Heart, $405,000; Satterthwaite, Anne, NIH, Regulation and Consequences of Ets1 Downregulation in B Cells, $539,236; Schmid, Sandra, NIH, The Clathrin Coated Vesicle Cycle, $533,419; Schoggins, John, NIH, Interactions between Type 1 and III Interferon During Resolution of HCV Infection, $102,087;

Self, David, Mount Sinai School of Med/NIH, Molecular Neurobiology of Drug Addiction, $283,119; Shaul, Philip, Univ of Cincinnati/NIH, Role of Endothelial and Macrophage ApoER2 in Atherosclerosis Modulation, $86,751; Skapek, Stephen, NIH, Tgf Beta 2 Controls p19Arf During Eye Development, $397,500; Stull, James, NIH, Signal Transduction Mechanisms to Myosin Phosphatase, $5,963; Terman, Jonathan, NIH, Molecular Mechanisms of Axon Guidance and Neural Connectivity, $39,750; Weakley, David, Emory Univ/NIH, Infant Aphakia Treatment Study, $19,361; Wolf, Steven, Geneva Fdn/Dept of Defense, Phases of Illness Paradigm (POIP), $40,257; Womack, Kyle, Baylor Res Inst/DHHS, North Texas Traumatic Brain Injury Model System, $95,318; Xie, Yang, NIH, Integrative Analysis to Identify Regulation Targets of RNA-Binding Proteins, $323,584; Zhang, Rong/Cullum, Munro, NIH, Exercise and Intensive Vascular Risk Reduction in Preventing Dementia, $542,333.

Non-Federal Awards

Bell, Kathleen, Univ of Washington/Dept of Defense, PTSD/TBI Clinical Consortium Coordinating Center and Clinical Sites Award (INTRuST), $91,273; Chopra, Rajiv, CPRIT, Recruitment of Rising Stars, $401,273; Cowell, Lindsay, Univ of Kansas/PCORI, Greater Plains Collaborative Clinical Data Research Network Phase II, $79,761; Falck, J Russell, Medical Coll of Wisconsin/Falk Med Res Trust, Novel Therapy for Kidney Disease, $112,200; Frohman, Elliot, Natl Multiple Sclerosis Soc, NMSS 5yr Institutional Clinical Care Fellowship Award, $116,875; Fujikawa, Teppei, Amer Heart Assoc, Hypothalamic Pathway Mediates Anti-type 1 Diabetes Actions of Leptin, $77,000; Glazer, Craig, Pulmonary Fibrosis Fdn, Pulmonary Fibrosis Foundation Care Center Network, $7,500; Greenberg, Benjamin, Transverse Myelitis Assoc, James T. Lubin Clinician Scientist Fellowship, $68,022; Henne, William, Searle Scholars Prgm, Novel Inter-Organelle Communication Networks in Lipid Metabolism and Neurological, $100,000;

Jaqaman, Khuloud, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $420,837; Jewell, Jenna, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $500,000; Jiang, Steve, CPRIT, Translating Online Adaptive Radiotherapy from Lab to Clinical Practice, $263,085; Lavery, Lawrence, Amer Diabetes Assoc, Negative Pressure Wound Therapy as a Drug Delivery System, $197,093; Liu, Li, UT Dallas/CPRIT, Optimizing Therapeutic Strategies Against Lung Cancer Using Multi-Modality Imaging, $150,000; Mahendroo, Mala, March of Dimes Fdn, Insights Into Diversity of Cervical Ripening Processes in Term and Preterm Birth, $100,000; Medin, Paul, CPRIT, Peripheral Nerve Tolerance to Single-Session Stereotactic Irradiation, $299,448; Mendelson, Carole, March of Dimes Fdn, Cellular Mechanisms in the Initiation of Labor, $100,000; Ngo, David, Arizona State Univ/NCURA, Model Policy Development to Reduce Administrative Faculty Burden, $3,843;

Okuda, Darin, Multiple Sclerosis Fdn, Bringing Healthcare Home, $24,250; Olson, Daiwai, Integra Lifesciences Corp, “Wait A Tic”, $8,650; Patel, Ashish, Emory Univ/Crohn’s & Colitis Fdn, Risk Stratification and Identification of Immunogenetic and Microbial Markers of Complicated Disease Course in Pediatric Crohn's Disease, $300; Pruitt, Sandi, Robert Wood Johnson Fdn, Multisector Solution to Build a Culture of Health Among Food Insecure Populations in Dallas County, $190,600; Scaglioni, Pier (Fellow A. Rabellino), Lymphoma Res Fdn, LRF Fellowship for Andrea, $55,000; Schoggins, John, Clayton Fdn, Identification of Host-Based Antiviral Targets, $300,000; Schwartz, David, CPRIT, Phase I Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Advanced Laryngeal Cancer, $279,794; Winick, Naomi, Children’s Hosp Philadelphia/PCORI, Home or Away From Home: Comparing Clinician and Patient/Family-Centered Outcomes, $26,998.

Industry Sponsored Awards, dollar amounts not available

Arnold, Susan, Phase 3 Long-Term Study of Lacosamide Oral Solution (syrup) or LCM Tablets for Pediatric Epilepsy sbjs with Partial-Onset Seizures, PRA Health Sciences/UCB Biosciences; Beg, Muhammad, Study of MED14736 and Tremelimumab for Unresectable Hepatocellular Carcinoma, Icon Clinical Res/Medimmune; Bezprozvanny, Ilya, Evaluation of Sigma 1 Receptor as Potential Target for Pridopidine in HD and AD Cellular Models, Teva Pharmaceutical Industries Ltd; Bird, John, Phase 3 Trial of Peanut Epicutaneous Immunotherapy with Viaskin Peanut in Peanut-Allergic Children (PEPTITES Study), Parexel Intl/DVB Technology; Blomkalns, Andra, Trial of Rivaroxaban for Early Discharge of Pulmonary Embolism from the ER, Janssen Research & Development LLC; Chin, Kelly, PORTICO: Study of Macitentan in Pts with Portopulmonary Hypertension, Actelion Pharmaceuticals Ltd; Chopra, Rajiv, Exploration of Methods for MRI-Guided Interventions at 3T, Profound Medical Inc;

Dimas, Vasiliki, Closure of Atrial Septal Defects with the Amplatzer Septal Occluder (ASO), St. Jude Medical Center; Jain, Raksha, Phase 1b Dose Escalation Study of QR-010 in Sbjs with Homozygous dF508 Cystic Fibrosis, Inc Research/PROQR Thera; Jain, Raksha, Phase 2 Study of N91115 For Pts with Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation and Being Treated with Lumacaftor/Ivacaftor (Orkambi), Greenphire/Nivalis Thera; Koch, Joshua, Phase 3b Withdrawal Trial of Titrated Oral Samsca (Tolvaptan) on Serum Sodium in Children & Adol Sbjs, Inc Research/Otuska; La Hoz, Ricardo, Phase 2 Dose Ranging Study of SCY-078 in Invasive Candidiasis, Medpace/Scynexis; Laetsch, Theodore, Phase 1 Study of Oral TRK Inhibitor LOXO-101 in Ped Pts with Advanced Solid or Primary Central Nervous System Tumors, Loxo Oncology Inc; Naqvi, Syed, Study of Xyrem in Pediatric Sbjs with Narcolepsy with Cataplexy, Inc Research/Jazz Pharma;

Patel, Ashish, Study of Humira in Ped Pts with Moderately to Severely Active Crohn's Disease – Cape, Mapi Group/ABBVJE; Rodriguez-Baez, Norberto, Registry for Adolescent and Pediatric Pts Who Received a Gilead Hepatitis C Virus Direct Acting Antiviral in Chronic Hepatitis C Infection Trials, Gilead Sciences Inc; Sarode, Ravindra, External Performance Evaluation of Innovance Heparin on BCS XP, Siemens Healthcare Diagnostics; Sathe, Meghana, Phase 3 Study of Liprotamase for Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency, RHO Inc/Anthera Pharma; Savani, Rashmin, RHAMM Function Blocking Peptides to Prevent Lung Inflammation, Novare Pharmaceuticals Inc; Siegwart, Daniel, Mirna Therapeutics Research Program, Mirna Therapeutics Inc; Stegner, Martha, Cost Effectiveness Analysis (CEA) of Brentuximab Vedotin, Children’s Hosp Philadelphia/Seattle Genetics; Trivedi, Jaya, Investigating Pompe Prevalence in Neuromuscular Medicine, UC Irvine/Genzyme;

Trivedi, Madhukar, Study of Fixed Doses of Intranasal Esketamine Plus and Oral Antidepressant in Adults with Treatment-Resistant Depression, Janssen Research & Development LLC; Vusirikala, Madhuri, Phase 2 Trial of IV Fenretinide Emulsion for Relapsed/Refractory Peripheral T-cell Lymphoma, Chiltern Intl/Cerrx; Westover, Arthur, Study of Response to Aripiprazole Once Monthly vs. Oral Antipsychotics in Non-adherent Outpts with Schizophrenia, Montana State Univ/Otsuka.