Awards for July 2016

Federal Awards

Abrams, John, NIH, Molecular and Genetic Control of Programmed Cell Death, $397,500; Bibb, James, NIH, The Role of Cdk5 in Stroke, $347,813; Boothman, David, NIH, RPRD1B/Kub5/Hera, An RNA Pol II Determinant That Controls PARPi & IR Sensitivity, $369,527; Borek, Dominika, Georgia State Univ/NIH, Therapeutics Targeting Filoviral Interferon-Antagonist, $21,176; Bowen, Michael, NIH, Predicting Diabetes Risk Using Glucose Data in the Electronic Medical Record, $170,961; Burstein, Ezra, NIH, Regulation of Copper Homeostasis by COMMD Proteins, $447,535; Chong, Benjamin, NIH, Molecular Markers in Discoid Lupus Erythematous, $160,380; Chook, Yuh Min, NIH, Molecular Biophysics Predoctoral Training Program, $136,008; Chopra, Rajiv, NIH, Image-Guided Doxorubicin Delivery for Pediatric Sarcomas, $555,305.

Debose-Boyd, Russell, NIH, Geranylgeranyl-Mediated Regulation of the Vitamin K2 Synthetic Enzyme UBIAD1, $331,929; Debose-Boyd, Russell, NIH, Elucidating Role of UBIAD1 in Sterol-Accelerated ERAD of HMG CoA Reductase, $302,100; Douglas, Peter, NIH, Cell Non-Autonomous Nature of the Heat Shock Response, $242,476; Eisch, Amelia, NIH, Molecular and Chemo Genetic Control of Dentate Gyrus Inputs: A Novel Approach, $200,895; Elmquist, Joel, NIH, Interactions of Leptin and Central Serotonin Systems, $374,583; Galindo, Rene, NIH, Defective Myoblast Fusion Signaling in Rhabdomyosarcoma Pathogenesis, $370,575; Gao, Jinming, NIH, Nanoprobe-Enabled Delineation of Tumor Margins for Improved Surgical Therapy, $370,385.

Garcia, Joseph, NIH, Mechanistic Studies and Translational Applications of Stress Signaling in Anemia, $404,791; Gerber, David, NIH, Evaluating Prior Cancer Exclusion Policy to Increase Lung Cancer Trial Accrual, $80,959; Goldstein, Joseph (Fellow L. Engelking), NIH, SREBP-Mediated Lipid Regulation in the Intestine, $147,246; Ivleva, Elena, NIH, Neural Network Biomarkers for Relational Memory and Psychosis in Schizophrenia, $169,668; Jia, Xun, NIH, Explore Random Sampling for Dose Reduction and Scatter Removal in Cone Beam CT, $222,745; Journeycake, Janna, UT HSC Houston/HRSA, Hemophilia Treatment Centers (SPRANS), $25,423; Kahn, Jeffrey, NIH, Innate Immune Activation by Respiratory Syncytial Virus, $242,813; Le, Lu Quang, US Dept of Defense, Malignant Peripheral Nerve Sheath Tumors: Models, Biology, and Translation, $278,250.

MacMillan, John, NIH, Center for High-Throughput Functional Annotation of Natural Products, $964,292; Mendelson, Carole, NIH, Mechanisms in the Regulation of SP-A Gene Expression, $461,635; Mineo, Chieko, NIH, Endothelial Basis of Obesity-Induced Insulin Resistance, $404,896; Mineo, Chieko, NIH, Endothelial SR-BI and Metabolic Health, $404,792; Monson, Nancy, NIH, Immune Profiling of Encephalitis, $258,325; Monteggia, Lisa, NIH, MeCP2 Dependent Transcriptional Repression & Neurotransmission, $397,500; Morrison, Sean (Fellow E. Piskounova), NIH, Identification and Functional Characterization of Metabolic Adaptations During Melanoma Metastasis, $27,491; Nugent, Alan, NIH, Development of Large Diameter Biodegradable Stents for Congenital Heart Disease, $93,761.

Okada, Pamela, Univ of Virginia/NIH, Established Status Epilepticus Treatment Trial (ESETT), $1,000; Olson, Eric, NIH, Metabolic Control by Myogenic MicroRNAs, Mediator and Myokines, $477,000; Olson, Eric (Fellow J. Papizan), NIH, The Role of DNA Methylation in Cardiac Regeneration, $58,002; Pascual, Juan, NIH, Modulation of Neural Function in Energy Failure, $347,813; Rice, Luke, Natl Science Fdn, Mechanistic Analysis of Microtubule Catastrophe, $250,490; Roberts, Todd, NIH, Neuronal Circuit Mechanisms for Learning During Social Interactions, $283,428; Sakhaee, Khashayar, NIH, Pathogenesis of Uric Acid Nephrolithiasis: The Multifaceted Role of Renal Lipids, $357,750; Satterthwaite, Anne, NIH, PIK3IP1 in B Cell Development and Function, $242,875.

Scherer, Philipp, NIH, Novel Mechanisms Regulating the Adipocyte-Brain-Hepatocyte Axis, $1,985,390; Shaul, Philip, NIH, Fc gamma RIIB and Inflammation-Related Vascular Disease, $357,750; Shiloh, Michael, NIH, Human Airway Microfold Cells in Mucosal Immunity to Bacterial Pathogens, $456,382; Sperandio, Vanessa, NIH, Sugar Regulation of EHEC Virulence, $397,500; Van Buren, Peter, NIH, Mechanisms of Increased Ambulatory Blood Pressure in Intradialytic Hypertension, $144,612; Wang, Jerry, NIH, Correction of B0 inhomogeneity Induced by Orthodontic Appliances in MRI, $157,500; Word, Ruth, NIH, Elastic Fiber Homeostasis in the Vaginal Wall, $323,490; Zigman, Jeffrey, NIH, Mechanisms of Ghrelin Secretion, $364,313.

Non-Federal Awards

Amatruda, James, Alex’s Lemonade Stand, DICER1-Driven Cancers: Models, Mechanisms and Therapies, $125,000; Amatruda, James (Fellow G. Kendall), Alex’s Lemonade Stand, Zebrafish Modeling of PAX3-FOXO1-Driven Rhabdomyosarcoma, $50,000; Brion, Luc, Gerber Fdn, Individualizing and Optimizing Nutrition to Prevent Metabolic Syndrome, $107,188; Chen, Zhijian (Fellow X. Tan), Cancer Research Inst, Phosphoinositide Regulation of STING Trafficking and Cancer Immunity, $56,500; Falck, J, Med Coll Wisconsin, EET-Induced Cardioprotection: Role of Opioids and Nitric Oxide (NO), $21,220; Gimpel, Nora, Texas A&M Res Fdn, Predoc Training in General Pediatric & Public Health Dentistry, $104,527; Gupta, Rana, Amer Heart Assoc, Unlocking the Thermogenic Potential of White Adipose Tissue to Combat Obesity, $77,000; Hill, Joseph (Fellow F. Altamirano Fulla), Amer Heart Assoc, Cardiomyocyte Mechanotransduction: Roles of Polycystin-1/2, $52,200;

Hooper, Lora (Fellow T. Harris-Tryon), Dermatology Fdn, Determining the Function of Resistin Like Molecule α (RELMα), $55,000; Jiang, Steve, CPRIT, Translating Online Adaptive Radiotherapy from Lab to Clinical Practice, $263,085; Jimenez, Patricia, Amer Soc For Reproductive Med, Understanding the Effect of Superovulation on Uterine Receptivity, $20,000; Klesse, Laura, Texas Neurofibromatosis Fdn, Cardiovascular Abnormalities in Pediatric Patients with Neurofibromatosis Type 1, $44,081; Le, Lu Quang (Fellow C. Liao), Dermatology Fdn, Mechanisms Regulating Hair Pigmentation and Development, $55,000; Le, Lu Quang (Fellow J. Brosseau), Children’s Tumor Fdn, Fibroblasts: The Missing Gap in Neurofibromatosis, $50,250; Leavey, Patrick, CPRIT, Using Imaging and Computational Tools to Improve Risk Stratification in Children, $317,802; Liu, Qinghua, Welch Fdn, Mechanistic Studies of the Drosophila RNA Interference Pathway, $60,000; Liu, Xin (Fellow L. Jiao), Amer Heart Assoc, Structural Mechanisms of Gene Silencing, $50,350;

Lum, Lawrence, CPRIT, A Molecularly Targeted Anticancer Therapeutic Strategy, $463,208; Madden, Christopher, UC San Francisco/Abbott Labs, Transforming Research and Clinical Knowledge in Traumatic Brain Injury, $20,000; Medin, Paul, CPRIT, Peripheral Nerve Tolerance to Single-Session Stereotactic Irradiation, $299,455; Nicastro, Daniela, March of Dimes Fdn, Structure and Function of the Central Pair Complex in Cilia and Flagella, $69,072; Olson, Daiwai (Fellow K. Moore), Daisy Fdn, Investigating Onset of Chemobrain in Chemotherapy Patients, $3,250; Olson, Eric (Fellow K. Baskin), Amer Heart Assoc, Med12 is a Transcriptional Mediator of Cardiac Contractile Function, $52,200; Radhakrishnan, Arun, Welch Fdn, Fluorescent Sensors for Measuring Cholesterol in Live Cells, $65,000; Raj, Ganesh, UT San Antonio/CPRIT, ESR1 Coregulator Binding Site Inhibitors (ECBIs) as Novel Therapeutics to Target Hormone Therapy Resistant, $263,158;

Reynolds, Kimberly, Gordon and Betty Moore Fdn, Decoding the Genome Using Evolutionary Statistics, $300,000; Reynolds, Kimberly, Gordon and Betty Moore Fdn, Conditional Gene Essentiality as Function of Cell Metabolic State, $56,250; Rhodes, Ramona, Amer Cancer Soc, End-of-Life Care for African Americans: Outpatient Intervention, $100,000; Rosen, Michael, Howard Hughes Medical Inst, HHMI 2016 Transformative Technology Program, $3,183,706; Sathe, Meghana, Cystic Fibrosis Fdn, Developing Innovative GastroEnterology Specialty Training, $32,111; Shaul, Philip (Fellow L. Huang), Amer Heart Assoc, Endothelial Cell SR-BI and Atherosclerosis, $48,600; Shay, Jerry (Fellow J. Peters-Hall), Cystic Fibrosis Fdn, Telomerase Immortalized HBE Cells to Study Primary Defects of Mutant CFTR, $47,930; Solow, Elizabeth, UNC Eshelman Sch of Pharmacy/PCORI, Enhancing Patient Ability to Understand and Utilize Complex Information, $44,724;

Wan, Yihong, CPRIT, Osteoclast Regulation of Bone Metastasis of Cancer, $361,206; Wang, Richard, Burroughs Wellcome Fund, Akt-Mediated Regulation of Autophagy & Tumorigenesis, $140,000; Xu, Jian, Amer Soc of Hematology, ASH Scholar Award, $50,000; Yang, Jennifer (Fellow E. Gosai), Merz USA, Merz SCI Fellowship 2017, $15,000; Yokoo, Takeshi, Radiological Soc of N Amer, Validation of Optimized Dixon-Based MRI Techniques for Noninvasive Evaluation, $76,000.

Industry Sponsored Awards, dollar amounts not available

Ahmad, Zahid, Regeneron Pharma, Study of Single and Multiple Doses of REGN1500 for Homozygous Familial Hypercholesterolemia; Beg, Muhammad, Merck Sharp & Dohme, Phase 3 Study of Pembrolizumab for Adenocarcinoma and Squamous Cell Carcinoma of the Esophagus; Bird, John, Aimmune Therapy, Peanut Allergy Oral Immunotherapy Study of AR101; Cheng, Jonathan, Nerves Inc, Dexterous Hand Control Through Fascicular Targeting (DEFT) - Phase 1; Frankel, Arthur, INCYTE, Phase 1/2 Study of MK-3475 with INCB024360 for Selected Cancers; Frankel, Arthur, Pfizer, Phase 1B/2 Study of Avelumab with Other Cancer Immunotherapies for Advanced Malignancies; Haley, Barbara, Innocrin Pharma, Phase 1/2 Study of VT-464 for Advanced Breast Cancer; Jain, Mamta, Gilead Sciences, Phase 3 Study of GS-9883/Emtricitabine/Tenofovir Alafenamide vs. Abacavir/Dolutegravir/Lamivudine in HIV-1 Infected, Antiretroviral Treatment-Naïve Adults;

Jones, Stephanie, Axsome Therapeutics, CREATE-1 Study; AXS-02 for Complex Regional Pain Syndrome Type 1; Journeycake, Janna, Biogen Ma, Evaluation of Recombinant Coagulation Factor VIII Fc Fusion Protein for Severe Hemophilia A; Luckett, Peter, Aerogen Ltd, Comparison of Vibrating Mesh Nebulizer versus Jet Nebulizer in Pediatric Asthma Patients; Mayo, Marlyn, Intercept Pharma, Phase 3 Study of Obeticholic Acid for Nonalcoholic Steatohepatitis; Sanghavi, Rinarani, Sucampo Pharma Americas, Study of Lubiprostone in Pediatric Subjects with Functional Constipation; Wickless, Heather, Actelion Pharma US, Study of Patients with Mycosis Fungoides Cutaneous T-Cell Lymphoma Treated with Valchlor.