Awards for August 2016

Federal Awards

Abrams, John (Fellow P. Kurtz), NIH, Non-Canonical Gene Regulation Through a Drosophila p53 Enhancer, $30,941; Amatruda, James, Children’s Hosp Phila/NIH, COG SMITSCS (U10CA180884), $13,438; Amatruda, James, Children’s Hosp Phila /NIH, NIH National Clinical Trials Network Grant, $6,775; Aroumougame, Asaithamby, NIH, Molecular Roles for Werner Syndrome Protein in Replication Fork Maintenance, $332,100; Badawy, Mohamed, Univ of California Davis/NIH, Validation of Decision Rules for CT Use in Children with Abdominal or Head Trauma, $69,392; Beutler, Bruce, Scripps Res Inst/NIH, U19 Project 1 Systems Approach, $849,554; Beutler, Bruce, NIH, Mutagenetic Analysis of LPS Responses, $813,237; Beutler, Bruce, Scripps Res Inst /NIH, U19 Core A Systems Approach, $802,258; Beutler, Bruce, Scripps Res Inst /NIH, U19 Core C Systems Approach, $315,853; Beutler, Bruce (Fellow E. Turer), NIH, Forward Genetic Analysis of Intestinal Homeostasis, $143,961;

Bezprozvanny, Ilya (Fellow D. Ryskamp), NIH, Synaptic Calcium Dysregulation in Huntington’s disease, $57,794; Brown, Sherwood, NIH, Treating Caregiver Depression to Improve Childhood Asthma: Impact and Mediators, $790,137; Brugarolas, James, NIH, UTSW SPORE in Kidney Cancer, $2,162,000; Burma, Sandeep, NIH, Augmented Homologous Recombination as a Mechanism of Acquired Temozolomide Resist, $176,131; Butovich, Igor, NIH, Biosynthesis and Physiological Roles of Extremely Long Chain Lipids in the Eye, $404,896; Carr, Bruce, NIH, Clinical Trials Network-Female Sites, $10,559; Carroll, Thomas, Maine Medical Center Res Inst/NIH, Application of Progenitor Niche Signals to Ex Vivo Nephrogenesis, $398,019; Chen, Christopher, Oakland Univ/NIH, Topographical Degradation-Xia NIH R01 Subcontract, $51,935;

Choi, Changho, NIH, Clinical Development of Cancer-Specific MRS Biomarkers in Malignant Gliomas, $329,925; Chook, Yuh Min, Univ of Penn/NIH, Splicing and Nuclear Transport of Influenza Virus mRNA, $32,384; Chuang, David, NIH, Structure and Function of Mitochondrial Protein Kinases, $474,963; Cobb, Melanie, NIH, Cancer Center Support Grant - UT Southwestern, $2,429,396; Cobb, Melanie, NIH, Cell and Molecular Biology Training Grant, $435,059; Danuser, Gaudenz (Fellow M. Driscoll), NIH, Bleb Functions in 3D Morphogenesis, $60,702; De Lemos, James (Fellow I. Neeland), NIH, Visceral Adiposity and Diabetes: Translating Form to Function Using Imaging, $153,360; Deberardinis, Ralph, Emory Univ/NIH, Emory Subcontract, $4,386; D'Orso, Ivan, NIH, Novell Small Molecules Reactivate Latent HIV and Sensitize Anti-Viral Therapies, $484,884;

Eisch, Amelia, NIH, Basic Science Training Program in Drug Abuse Research, $529,748; Fontoura, Beatriz, NIH, Crosstalk Between Human mRNA Nuclear Export and Polyadenylation Machineries, $405,000; Fontoura, Beatriz, Univ of Penn/NIH, Splicing and Nuclear Transport of Influenza Virus mRNA, $32,384; Fontoura, Beatriz, Mount Sinai/NIH, Chemical Intervention of Influenza Virus RNA Nuclear Export, $27,605; Ge, Wuping, NIH, An Optogenetic Approach to Study Axonal Repair in the Brain, $243,000; Gruchalla, Rebecca, Univ of Wisconsin/NIH, ICAC3-Inner City Asthma Consortium 3, $610,617; Henkemeyer, Mark, Texas A&M HSC/NIH, Mechanism of Ephrin Signaling in Mammalian Palatal Fusion, $28,162; Henne, William, NIH, PXA Domain-Containing Proteins in Lysosome Function and Lipid Metabolism, $404,896;

Herz, Joachim, NIH, Physiology and Pathophysiology of Apolipoprotein E Receptor-2 Splicing in Alzheimer, $404,791; Hobbs, Helen (Fellow M. Mitsche), NIH, Determining the Function of PNPLA3 Utilizing Metabolomic, $103,204; Holland, William, NIH, Adiponectin Receptors and S1P Signaling in Beta Cell Survival and Proliferation, $239,262; Holland, William (Fellow J. Johnson), NIH, Sphingolipid-Mediated Dysregulation of Glucose and Energy Homeostasis by POMC, $31,448; Hsieh, Jenny, Res Fdn for Mental Hygiene/NIH, Diverse Roles of Adult Dentate Gyrus Neurogenesis, $60,671; Hsieh, Jer-Tsong, NIH, Developing Targeted Therapy with Prostate Cancer Specific Nanomedicine, $315,210; Huang, Chou-Long, NIH, Klotho and Chronic Kidney Disease, $238,500; Jain, Mamta, Massachusetts Gen Hosp/NIH, Randomized Trial to Prevent Vascular Events in HIV-REPRIEVE, $145,000; Jiang, Youxing, NIH, Structural Mechanisms of Ion Selectivity and Gating in Tetrameric Cation Channels, $315,900; Johnson, Mark, Univ of Miami/NIH, MyRIAD, $12,980; Khemani, Pravin, Massachusetts Gen Hosp /NIH, NN105 (STAIR), $31,969;

Kim, James, Dept of Defense, Targeting of Cancer Stem Cells and Their Microenvironment in Early Stage Mutant K, $190,794; Kim, Taekyung, NIH, The Epigenetic Mechanism of Enhancer RNA in Behavioral Plasticity, $347,813; Kitchell, Ellen, Health Resources and Services Admin, Ryan White Title IV Women, Infants, Children: AIDS, $1,038,418; Kohler, Jennifer, NIH, Photocrosslinking Probes to Discover Glycan-Dependent Interactions, $314,119; Lee, William, NIH, Hepatitis B Research Network Clinical Centers, $196,114; Lega, Bradley, NIH, Comparison of fMRI and iEEG Metrics of Hippocampal Connectivity During Memory Encoding, $214,508; Li, Wen-Hong, Vitalquan LLC/NIH, Fluorescent Probes for Tracking Insulin Secretion in Therapeutic and Diagnostic Devices, $152,947; Maalouf, Naim, NIH, Optimizing Fluid Therapy and Stent Management in Children and Adults with Nephrol, $720,590; Macdonald, Raymond, Univ of Utah/NIH, Suppression of Pancreatic Tumorigenesis by the PTF1 Transcription Factor Network, $100,534;

Mahendroo, Mala, NIH, Steroid Hormones Modulate Cervical ECM Function in Term and Preterm Birth, $381,539; Makam, Anil, NIH, Role of Long-Term Acute Care Hospitals, $121,469; Maldjian, Joseph, Wake Forest Univ/NIH, iTAKL: High School Football, $244,494; Maldjian, Joseph, Wake Forest Univ /NIH, Cerebrovascular Disease and Cognitive Performance in African Americans, $203,969; Mendell, Joshua, NIH, The Intersection of RNA Biology and Tumor Biology, $772,009; Nicastro, Daniela, NIH, Resolution Improvement for Cellular CryoEM to Study Dynamic Assemblies in Cells, $356,309; Norgard, Michael, NIH, Molecular Microbiology Training Grant, $298,306; Olson, Eric (Fellow A. Bookout), NIH, Regulation of Systemic Energy Metabolism by Myokines, $58,002; Pan, Duojia, NIH, Control of Cell Number in Developing Retina, $405,000;

Petroll, Matthew, NIH, Assessment of Corneal Fibroblast Biomechanical Behavior, $400,155; Petroll, Matthew, NIH, Modulation of Corneal Wound Healing Using Pre-Surgical Dietary Restriction, $200,280; Pfeiffer, Julie, NIH, Enteric Virus-Microbiota Interactions, $420,757; Pfeiffer, Julie (Fellow C. Robinson), NIH, Sex-Dependent Replication of Coxsackievirus, $119,760; Phelps, Katherine, NIH, Laser Scanning Confocal for UT Southwestern Live Cell Imaging Facility, $455,255; Ravikumar, Priya, Duke Univ/NIH, Relationship Between Alpha-klotho and Chronic Lung Disease, $9,999; Rosen, Michael (Fellow J. Ditlev), NIH, Stability and Dynamics of Nephrin/Nck/N-WASp Clusters on Membranes, $58,002; Rothenfluh, Adrian, NIH, Engineering Drosophila that Self-Administer Cocaine, $202,396; Rutherford, Cynthia, UT HSC Houston/HRSA, Hemophilia Treatment Center (SPRANS), $23,277;

Sadek, Hesham, NIH, Role of Meis 1 in Regulation of Cardiomyocyte Prolif, $504,559; Scherer, Philipp (Fellow J. Stern), NIH, The Role of Alpha-Cell Mitochondria in Glucagon Secretion and Glucose Homeostasis, $59,970; Scherer, Philipp (Fellow J. Xia), NIH, Intracrine Metabolic Effects of Adiponectin Mutants, $39,876; Scherer, Philipp Fellow Q. Wang), NIH, Converting More Brown Adipocytes from Resting to Active State, $110,462; Shiloh, Michael, NIH, Carbon Monoxide Resistance in Mycobacterium Tuberculosis, $397,500; Skapek, Stephen, Children’s Hosp Phila/NIH, COG SMITSCS, $34,766; Skapek, Stephen, Children’s Hosp Phila/NIH, COG STS Biology Vice Chair, $20,157; Sperandio, Vanessa, NIH, SdiA Regulation of EHEC Virulence, $373,650; Sperandio, Vanessa (Fellow E. Cameron), NIH, The Role of the Human Gut Microbiota in Modulating Virulence, $54,294; Strand, Douglas, NIH, Interplay Between Stem Cells and Inflammation in Benign Prostatic Hyperplasia, $80,980;

Tagliabracci, Vincent, NIH, Phosporylations of FGF23 Coordinates Crosstalk Between the Skeleton and Kidney, $248,999; Terada, Lance, NIH, Epigenetic Effects of the Premalignant Field, $357,464; Torres, Fernando, Cincinnati Children’s Hosp/NIH, National Biological Sample & Data Repository for Pulmonary Arterial Hypertension, $15,200; Trivedi, Madhukar, NIH, Translational Research Activities in Neuropsychiatry (TRAIN), $199,843; Trivedi, Madhukar (Fellow M. Toups), NIH, Gene Expression to Expand Knowledge of Inflammatory Depression, $180,360; Tsai, Peter, NIH, Mechanisms Underlying the Cerebellar Contribution to Autism, $190,458; Wang, Jing, UT Arlington/NIH, Recovery of True Scatter in Blocked Regions for Blocker-Based Scatter Correction, $9,715; Williams, Kevin, NIH, Central Mechanisms Regulating Acute Leptin and Insulin Signaling, $357,750; Winick, Naomi, Children’s Hosp Phila/NIH, NIH NCTN Scientific Leadership, $29,986; Winick, Naomi, St. Jude Children’s Res Hosp/NIH, Web-Based Physical Activity Intervention for Children with ALL, $11,479;

Wise, Carol, NIH, Genomic Approaches to Understanding and Treating Scoliosis, $6,000; Womack, Kyle, Univ of So Calif/Dept of Defense, Effects of Traumatic Brain Injury and Post-Traumatic Stress Disorder, $47,000; Word, Ruth, NIH, Cervical Ripening and Histone Acetylation, $200,425; Xiao, Guanghua, NIH, Integrative Analysis to Identify Therapeutic Targets for Lung Cancer, $329,925; Yamazaki, Shin, NIH, Identification of the Anatomical Locus for the Food-Entrainable Circadian Oscillator, $202,500; Yin, Helen Lu, NIH, Mechanisms of Disease & Translational Science, $135,268; Zang, Qun, NIH, Pathological Responses to Mitochondrial ROS in Sepsis-Induced Cardiac Dysfunction, $291,600; Zhang, Chun-Li, NIH, Induced Adult Neurogenesis for Parkinson's Disease, $476,966; Zhang, Rong (Fellow T. Tarumi), NIH, Midlife Brain Plasticity: Exercise and Vascular Function, $118,275;

Zhang, Xuewu, NIH, Signaling and Regulation Mechanisms of Plexin, $321,215; Zhong, Qing, NIH, Biochemical Dissection and Reconstitution, $319,950; Zigman, Jeffrey, NIH, Role of Ghrelin in the Counterregulatory Response to Insulin-Induced Hypoglycemia, $121,500; Zinn, Andrew, NIH, Medical Scientist Training Program at UT Southwestern, $917,600. 

Non-Federal Awards

Banaszynski, Laura (Fellow S. Martire), American Italian Cancer Fdn, Exploring the Role of Histone H3.3 Mutation in Pediatric Cancer, $40,000; Bird, John, Food Allergy Res & Education, FARE Clinical Network, $120,000; Blount, Paul, Welch Fdn, Determining Lipid-Protein Interactions for a Channel Gated by Membrane Tension, $60,000; Chen, Chuo, Welch Fdn, Development of Anticancer Immunotherapeutic Agents, $65,000; Chen, Zhijian, Lupus Res Inst, Roles of the cGAS Pathway in Lupus, $250,000; Chopra, Rajiv, CPRIT, Recruitment of Rising Stars, $416,053; Conrad, Nicholas, Amer Cancer Soc, Posttranscriptional Regulation of Metabolic Genes Involved in Cancer, $198,000; Corey, David, Friedreich Ataxia Research Alliance, $123,360; De Brabander, Jef, Welch Fdn, Novel Heterocyclizations for Natural Product Synthesis, $75,000;

Deberardinis, Ralph, UT MD Anderson/CPRIT, Exploiting Molecular and Metabolic Dependencies to Optimize Personalized Therapies, $105,260; Fu, Yang-Xin (Fellow H. Tang), Cancer Res Inst, Tumor-Specific LIGHT Targeting for Cancer Immunotherapy, $58,500; Gardner, Lisa (Fellow A. Nevarez), Howard Hughes Medical Inst, HHMI Fellowship-Gilliam, Nevarez, A., $46,000; Gibson, Jay, Simons Fdn, Foxp1 Orchestration of Neuronal Function in the Striatum, $146,690; Goldsmith, Elizabeth, Welch Fdn, Kinetics and Chemistry of the p38 MAPK Cascade, $65,000; Henne, William, Searle Scholars Program, Novel Inter-Organelle Communication Networks in Lipid Metabolism and Neurological, $100,000; Hill, Joseph, Amer Heart Assoc, UT Southwestern Medical Center Strategically Focused Prevention Research Center, $954,800; Hsieh, Jenny (Fellow Z. Lybrand), Amer Epilepsy Soc, Lybrand Fellowship, $45,000; Huber, Kimberly, Simons Fdn, Defining the Translational Landscape in Mouse Models of Autism, $137,500; Hulleman, John, BrightFocus Fdn, Genetic Manipulation of Fibulin-3 for Treatment of ML/Dry AMD, $80,000;

Jain, Raksha, Cystic Fibrosis Fdn, Cystic Fibrosis Foundation-Adult Care Center, $152,160; Jiang, Jin, Welch Fdn, Study of Chemical Modification in Cell Signaling, $100,000; Kohler, Jennifer, Welch Fdn, Discovering Toxin Receptors with Photocrosslinking Sugars, $100,000; Kraus, William (Fellow B. Parameswaran), Amer Heart Assoc, The Role of PARP-3 in Adipogenesis, $50,350; Laetsch, Theodore, Hosp For Sick Children/Focused Ultrasound Fdn, Pediatric Focused Ultrasound Computational Data Center and Registry, $10,980; Li, Bing, Welch Fdn, Mechanisms of Histone H3 Lysine-to-Methionine Mediated Chromatin Misregulation, $65,000; Liou, Jen, Welch Fdn, Novel Imaging Probes for Investigating ER Membrane Contact Sites, $65,000; Liu, Zhi-Ping, Amer Heart Assoc, FoxO4-Regulated Post-Myocardial Infarction Left Ventricular Remodeling, $77,000; Luo, Weibo, Susan G. Komen Breast Cancer Fdn, Epigenetic Regulation of Hypoxia-Inducible Factor 1 Activity in Breast Cancer, $150,000; MacMillan, John, Welch Fdn, Role of Non-Enzymatic Transformations in Natural Product Biosynthesis, $75,000;

Mattrey, Robert, CPRIT, Developing and Translating Ultrasound and Nanotechnology to Enhance Cancer Imaging, $1,200,000; Mirzaei, Hamid, Welch Fdn, Development of a Fully Automated 3D Separation Platform, $60,000; Nguyen, Benjamin, Medtronic Neuromodulation, Medtronic BIM Fellowship FY2017, $20,000; O'Donnell-Mendell, Kathryn, CPRIT, Identification of Novel Melanoma Metastasis Driver Genes through Transposon-Mediated Mutagenesis, $100,000; O'Donnell-Mendell, Kathryn, LUNGevity Fdn, Dissecting Novel Mechanisms of Lung Cancer Pathogenesis, $100,000; O'Donnell-Mendell, Kathryn, Welch Fdn, Dissecting Novel Mechanisms of Lung Cancer Pathogenesis, $65,000; Orth, Kim, Welch Fdn, Using Chemistry and Genetics with VopQ to Decipher Vacuolar Fusion Events, $80,000; Powell, Craig (Fellow C. Ochoa), Autism Science Fdn, The Role of Cul3 and Kctd13 in Neuronal Function, $25,000; Ready, Joseph, CPRIT, 209Chemistry, $399,830; Ready, Joseph, Welch Fdn, Synthesis and Application of Optically Active Allenes, $75,000;

Schwartz, David, CPRIT, Phase I Trial of Stereotactic HYpofractionateD RadioAblative, $279,786; Singal, Amit, Baylor/CPRIT, The Texas Hepatocellular Carcinoma Consortium, $86,276; Skapek, Stephen (Fellow S. John), St. Baldrick’s Fdn, Targeting LILRB4 by CAR-T Cells for the Treatment of Pediatric AML, $89,232; Tagliabracci, Vincent, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Member, $500,000; Tu, Benjamin, Welch Fdn, Selective Regulation of Metabolism by a Conserved Inhibitor of TORC1, $110,000; Uyeda, Kosaku, Welch Fdn, Biochemical Mechanism of Glucose Sensing & Regulation, $65,000; Vernino, Steven, Dysautonomia International, Muscarinic and Sjögren’s Associated Antibodies in Postural Orthostatic Tachycardia Syndrome, $50,000; Wang, Sam (Fellow I. Nassour), Chirhoclin Res Inst, The Role of ARID1A in Pancreatic Mucinous Cystic Lesions, $5,000; Wang, Zhigao, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Member, $500,000; Yu, Yonghao, Welch Fdn, Large-Scale Isolation and Identification of Poly-ADP-Rib, $80,000; Zhang, Chun-Li, Welch Fdn, Chemical Regulation of Human Motor Neurons, $80,000.

Industry Sponsored Awards, dollar amounts not available

Aquino, Victor, Chimerix, Expanded Access Protocol to Provide Brincidofovir for Serious Adenovirus Infection or Disease; Bartolome, Sonja, Eiger Biophama, Phase 2 Study of Ubenimex for Pulmonary Arterial Hypertension; Beg, Muhammad, Bristol-Myers Squibb, Phase 3 Study of Nivolumab vs. Sorafenib for Advanced Hepatocellular Carcinoma; Chin, Kelly, Actelion Pharma, REPAIR: Right Ventricular Remodeling in Pulmonary Arterial Hypertension; Corbin, Ian, Remeditex Ventures, Tolerability and Efficacy Studies of LDL-DHA as an IND Candidate; Drazner, Mark, St. Luke’s Hosp/AstraZeneca, Dapagliflozin Effect on Diabetes Patients with Heart Failure; Falck, J. Russell, Medical College of Wisconsin, Design and Synthesis of EET Mimetics; Gurram, Bhaskar, Janssen Res & Dev, Phase 4 Study of Serum Infliximab in Pediatric Patients with IBD; Jain, Raksha, Greenphire/Vertex, Phase 2a Study of VX-371 for Cystic Fibrosis, Homozygous for F508del-CFTR Mutation, and Treated with Orkambi;

Kahn, Jeffrey, Inventiv Health/Alios BioPharma, Study of ALS-008176 for Infants Hospitalized with Respiratory Syncytial Virus Infection; Khan, Saad, Precog/Celldex, Phase 3 Study of Glembatumumab Vedotin for Carcinoma of the Lung; Kutz, Joe, Duke Univ/Assoc of Migraine, Assessment of Migraine and Other Headache Types in Otolaryngology; Laetsch, Theodore, Eli Lilly, Phase 1 Study of Olaratumab and Doxorubicin for Pediatric Cancer Patients; Lingvay, Ildiko, DrugDev/Novo Nordisk, Pioneer 6 - Cardiovascular Outcomes: Study of Oral Semaglutide for Type 2 Diabetes; Mayo, Marlyn, Intercept Pharma, Phase 3b Study of Obeticholic Acid for Primary Biliary Cirrhosis; Monteggia, Lisa, Astellas Pharma, Examine Circadian Behavior in Mouse Models of Psychiatric Disorder; Pascual, Juan, Chinalink Intl, Genes and Dystonia; Phillips, Margaret, Medicines For Malaria, Blood Nucleotide Analysis After Dosing of Dihydroorotate Dehydrogenase Inhibitors in Animals and Man; Sarma, Satyam, Harvard Clin Res Inst/Corvia Med, Study to Evaluate the Corvia Medical IASD System.