Federal Awards

Attanasio, Massimo, NIH, Role of GLIS2 in Development of Cystic Kidney Disease, $345,825; Bezprozvanny, Ilya, NIH, Presenilins and Neuronal Calcium Dyshomeostasis, $459,113; Bobulescu, Ion, NIH, Protein Phosphatase Regulation of Principal Renal Sodium Transporter NHE3, $86,847; Booth, Timothy, Children’s Hosp of Phila/NIH, CHOP-COG Diagnostic Imaging Review, $2,800; Brekken, Rolf, Univ of Houston/NIH, Phosphatidylserine Targeted Tumor Cell Lytic Peptoids, $84,185; Burma, Sandeep, NASA, Mouse Glioma Models to Estimate Cancer Risks from HZE Particle Exposure, $448,394;

Cobb, Melanie, NIH, Insulin-Regulated MAP Kinase Pathways, $497,201; Cobb, Melanie, NIH, Cell & Molecular Biology Training Program, $428,657; Deberardinis, Ralph, NIH, Metabolic Regulators of Tumor Cell Growth – Supplement, $9,001; Eisch, Amelia, NIH, Basic Science Training Program in Drug Abuse Research – Supplement, $16,329; Falck, J, New York Med Coll/NIH, Hormonal Regulation of Blood Pressure, $127,298; Hill, Joseph, NIH, STIM1: Master Regulator of Calcium Homeostasis in Cardiomyocytes, $391,537;

Hsieh, Jenny, Res Fdn for Mental Hygiene/NIH, Diverse Roles of Adult Dentate Gyrus Neurogenesis, $60,761; Huber, Kimberly, NIH, Mechanisms of Neocortical and Sensory Hyperexcitability in Fragile X, $1,747,999; Huet, Beverley, UNT HSC/NIH, Role of HIV-1 Nef in Acceleration of HCV-Mediated Liver Disease, $10,532; Jain, Mamta, Virginia Commonwealth Univ/NIH, HBV/HIV Co-Infection Research Network, $70,217; Jain, Mamta, Mass Genl Hosp/NIH, Randomized Trial to Prevent Vascular Events in HIV – REPRIEVE (A5332), $5,000; Konopka, Genevieve, NIH, Identification of Human-Relevant CLOCK Molecular Signaling Pathways, $201,875;

Lenkinski, Robert, GE Global Res Center/NIH, Improving Specificity of Breast MRI through Improved DWI, $200,000; Levine, Beth, NIH, Infectious Diseases Training Program, $121,357; Li, Wen-Hong, NIH, Photonic Probe and Techniques for Biological Imaging Applications, $333,900; Mendell, Joshua, NIH, c-Myc-Regulated MicroRNAs in Normal and Pathologic Cellular Physiology, $293,037; Norgard, Michael, NIH, Molecular Microbiology Training Grant, $291,610; Olson, Eric, NIH, Heart Repair Through Reprogramming of Cardiac Cell Fate, $523,307; Orth, Kim (Fellow D. Salomon), NIH, Type VI Secretion System MIX-Effectors and their use as Anti-Bacterial Agents, $83,917;

Patel, Vishal, NIH, MicroRNAs: New Regulators of Disease Progression in Polycystic Kidney Disease, $363,375; Potts, Ryan, NIH, Regulation of WASH-mediated Endosomal Protein Recycling, $310,888; Powell, Craig, NIH, Striatal Synaptic Abnormalities in Models of Autism, $397,500; Ramos-Roman, Maria, NIH, Effect of Lactation on Ectopic Lipid After Gestational Diabetes, $198,750; Reese, Michael, NIH, Interrogating the Interaction of Toxoplasma Secreted Factors Host Immune Response, $106,553; Roth, Michael, NIH, Lung Cancer Oncogenotype-Selective Drug Target Discovery, $706,409;

Rutherford, Cynthia, UT HSC Houston/CDC, Public Health Surveillance for Prevention of Complications of Bleeding and Clotting Disorders, $19,088; Schaffer, Joseph, RTI Intl/NIH, NICHD Pelvic Floor Disorders Network, $71,987; Starr, Adam, Johns Hopkins Univ/Dept of Defense, Major Extremity Trauma Research Consortium (METRC I), $178,526; Story, Michael, Colorado State Univ/NASA, NASA Specialized Center of Research on Radiation Carcinogenesis, $299,298; Takahashi, Joseph, NIH, Transcriptional Architecture and Chromatin Landscape of Circadian Clocks in Aging Tissue, $269,902; Takahashi, Joseph, UT HSC Houston/NIH, Role of Clock-Modulating Small Molecules Against Aging, $47,700;

Tambar, Uttam, NIH, Stereoselective Rearrangements for Synthesis of Bioactive Small Molecules, $310,050; Tambar, Uttam, Univ of Cal Davis/DARPA, PREDICTOR Predictive REaction Design via Informatics, Computation and Theories Of Reactivity, $49,618; Tiro, Jasmin, NIH, Developing a Self-Persuasion Intervention Promoting Adolescent HPV Vaccination, $434,854; Toto, Robert, NIH, UT Southwestern Center for Translational Medicine – UL1, $5,216,957; Toto, Robert, NIH, UT Southwestern Center for Translational Medicine – KL2, $953,416; Toto, Robert, NIH, UT Southwestern Center for Translational Medicine – TL1, $108,776;

Toups, Marisa, NIH, Gene Expression to Expand Knowledge of Inflammatory Depression, $180,360; Tsai, Peter, NIH, Mechanisms Underlying the Cerebellar Contribution to Autism, $190,457; Van Buren, Peter, NIH, Mechanisms of Increased Ambulatory Blood Pressure in Intradialytic Hypertension, $144,612; van Oers, Nicolai (Fellow A. Hoover), NIH, The lnc to Clinical Abnormalities in 22q11_2 Deletion DiGeorge Syndrome, $30,808; Wang, David, NIH, Hedgehog Signaling in the Development of Barrett's Esophagus, $280,708; Whitworth, Louis, UT HSC Houston/NIH, ATACH-II (Antihypertensive Treatment of Acute Cerebral Hemorrhage) Study, $7,820;

Witkiewicz, Agnieszka, NIH, Impact of ErbB2 and RB Pathways on DCIS Progression and Treatment, $326,689; Wolf, Steven, NIH, Training in Trauma, Inflammation, Sepsis and Critical Care, $27,300; Wyckoff, Myra, RTI Intl/NIH, NICHD Neonatal Research Network, $8,393; Xu, Jian, NIH, Mechanistic Roles of BCL11A in Globin Switching and Fetal Hemoglobin Silencing, $135,703; Yin, Helen, NIH, Mechanisms of Disease & Translational Science, $99,974; Zhang, Chun-Li, NIH, Reprogramming the Human Glioma Genome, $201,875.

Nonfederal Awards

Albanesi, Joseph Peter, Michael J Fox Fdn For Parkinsons Rsrch, Mechanisms of LRRK2 Membrane Association, $55,000; Argenbright, Keith, CPRIT, The C-SPAN Coalition: Colorectal Screening and Patient Navigation, $1,600,000; Ariizumi, Kiyoshi, Astellas Pharma Inc, Sponsored Research Agreement OTD Contract #107282, $85,116; Bachoo, Robert, CPRIT, Acetate may be a Key Substrate Driving Growth in Early Stage Breast Cancer in Patients, $100,000; Blount, Paul, Welch Fdn, Determining Lipid-Protein Interactions for a Channel Gated by Membrane Tension, $60,000; Bruick, Richard, Welch Fdn, Analytical Approaches to Characterize Iron- and Oxygen-Sensing Mechanisms Governing Cellular Iron Homeostasis, $60,000;

Burgess, Shawn, Welch Fdn, Dysregulation of Intracellular Lipid Synthesis During Disease, $60,000; Chen, Zhijian, Welch Fdn, Biochemical Mechanism of MAVS Activation by Prion-Like Polymerization, $100,000; Chiang, Cheng-Ming, Welch Fdn, Mechanistic Action of BET Compound Inhibitors in Cancer Therapeutics, $60,000; Chook, Yuh Min, Welch Fdn, Mechanisms of Nuclear Export Cargo Dissociation, $75,000; Choti, Michael, VentureWell, Safe C Cesarean Section Assist Device-Stage 2, $20,000; Chuang, David, Welch Fdn, Mitochondrial Signaling by Reversible Phosphorylation, $60,000;

Cobb, Melanie, Welch Fdn, Regulatory and Catalytic Properties of MAP Kinase Cascades, $60,000; Conrad, Nicholas, Welch Fdn, Biochemical Analysis of a Nuclear Poly(A)-Dependent RNA Decay Pathway, $60,000; Corey, David, Welch Fdn, Recognition of Cellular Nucleic Acid Targets by Synthetic Oligomers, $100,000; Danuser, Gaudenz, CPRIT, Bioinformatics Core Facility at UT Southwestern Medical Center, $1,314,994; Danuser, Gaudenz, Welch Fdn, Probing Oncogenic Functions of Vimentin Filaments by Small Molecule Screens, $60,000; De Brabander, Jef, Welch Fdn, Novel Heterocyclizations for Natural Product Synthesis, $75,000;

Deberardinis, Ralph, Welch Fdn, Glutamine-dependent Reductive Carboxylation: a Metabolic Achilles Heel in Cancer, $100,000; DeMartino, George, Welch Fdn, Regulation of Proteasome Function by Reversible SUMOylation, $60,000; Glass, Donald, Dermatology Fdn, Determining the Genetic Causes of Keloid Formation, $55,000; Grishin, Nick, Welch Fdn, Structure Mechanism of Circadian Clock-Mediated Transcription Activation, $75,000; He, Yu-Guang, Vital Art and Science/TETF, Low-Cost Home Vision Self-Test, $54,077; Hibbs, Ryan, Welch Fdn, Structural Basis of Chemical Transmitter Recognition by Pentameric Ligand-Gated Ion Channels, $60,000;

Holland, William, Juvenile Diabetes Res Fdn, Sphingosine Kinases in Beta Cell Survival and Proliferation, $150,000; Hsieh, Jenny, Welch Fdn, Chemical Regulation of Adult Hippocampal Neurogenesis and Memory, $75,000; Jiang, Qiu-Xing, Welch Fdn, CryoEM Study of IP3R in New Chemically-Engineered Membrane Systems, $75,000; Jiang, Youxing, Welch Fdn, Structural and Functional Studies of RCK-Regulated Potassium Channel, $100,000; Johnson, Jane, CPRIT, Identifying Inhibitors of Ascl1 to Block Growth of Malignant Neuroendocrine, $100,000; Konopka, Genevieve (Fellow M. Co), Autism Science Fdn, Genetics Underlying Brain Connectivity in ASD, $25,000;

Laetsch, Theodore, Bear Necessities Ped Cancer Fdn, Maximizing the Therapeutic Impact of CDK4/6 Inhibition in Rhabdomyosarcoma, $50,000; Lee, Simon, CPRIT, BSPAN3: Breast Screening and Patient Navigation for Rural and Undeserved, $499,201; Li, Wen-Hong, Juvenile Diabetes Res Fdn, Biomarkers of Functional Beta Cells, $286,880; Lum, Lawrence, Welch Fdn, Modulation of Canonical Wnt Pathway Activity Using Small Molecules, $75,000; Mahendroo, Mala, Washington Univ in St. Louis/March of Dimes, Transdisciplinary Center, $21,781; McAdams, Carrie, Hogg Fdn for Mental Health, Attribution Biases and Recovery for Mental Health Consumers with Anorexia Nervosa, $19,250;

Nicastro, Daniela, CPRIT, High-Resolution Visualization of Native, Dynamic DNA-Interacting Complexes Inside, $1,927,646; Norgard, Michael, Welch Fdn, Structure and Function of a Novel Bacterial Regulator, $60,000; O'Donnell-Mendell, Kathryn, CPRIT, Identification of Novel Melanoma Metastasis Driver Genes through Transposon-Media, $100,000; Olson, Daiwai (Fellow M. Le Danseur), Sigma Theta Tau Intl, Is the CABIC Clean Intermittent Catheterization Patient Education Effective (ICPEE)?, $1,000; Pasare, Chandrashekhar, Welch Fdn, Biochemical Role of IRAK-1 in Regulating Caspase-1 Activation and Cleavage, $60,000; Phillips, Margaret, Welch Fdn, Purine Salvage Pathways as Potential Drug Targets in Trypanosoma Brucei, $100,000;

Potts, Ryan, Welch Fdn, Therapeutic Targeting of Melanoma Antigen (MAGE) Genes, $60,000; Rizo-Rey, Jose, Welch Fdn, NMR Methods to Study Membrane Proteins in Lipid Bilayers, $75,000; Rosen, Michael, Welch Fdn, Phase Transitions in Multivalent Macromolecular Assembly, $100,000; Rosenbaum, Daniel, Welch Fdn, Structural Studies of Active and Inactive Conformations of GPCRs, $60,000; Sathe, Meghana, Cystic Fibrosis Fdn, Developing Innovative GastroEnterology Specialty Training, $32,400;

Schmid, Sandra, CPRIT, Dynamin GTPase: A Novel Pro-Apoptotic Cancer Therapeutic Target, $100,000; Schmid, Sandra, Welch Fdn, Conformational Dynamics and Regulation of Dynamin, $60,000; Scott, Daniel, Fdn for Surgical Fellowships, SCIMS Fellow Funding, $20,000; Tambar, Uttam, Welch Fdn, Stereoselective Allylic Functionalization of Olefins, $60,000; Terman, Jonathan, Welch Fdn, Chemistry and Enzymology of MICAL Family Oxidoreductases, $75,000; Wan, Yihong, Welch Fdn, Biochemical Characterization of PAFAH Regulation by Macrophage VLDLR, $75,000; Wang, Zhigao, Welch Fdn, Biochemical Identification of Proteases Involved in Necrotic Cell Death Execution, $60,000; Westover, Kenneth, Welch Fdn, Characterization of Covalent K-Ras Inhibitors, $60,000;

White, Michael, Welch Fdn, Analysis of Functional Significance of Complex Protein/Protein Interactions, $100,000; Winter, Sebastian, Welch Fdn, Metabolism of Salmonella Typhimurium in the Inflamed Gut, $60,000; Yu, Hongtao, Welch Fdn, Biochemical and Structural Analysis of Cohesin and Its Regulators, $100,000; Zhang, Chengcheng, Welch Fdn, Small Molecule Modulators of Angptl Receptor for Stem Cell Expansion and Leukemia Treatment, $60,000; Zhang, Xuewu, Welch Fdn, Structural Basis for the Interaction Between Class B Plexins and PDZ-RhoGEF/LARG, $60,000; Zhong, Qing, Welch Fdn, Regulation of the Class III P13K by Nutrient-Sensing Kinases in Autophagy, $60,000.

Industry Sponsored Awards, dollar amounts not available

Diercks, Deborah, Clinical Performance of Elecsys Troponin T Gen 5 for Symptoms of Acute Coronary Syndrome, Roche Diagnostics Corp; Emslie, Graham, Study of Vilazodone in Pediatric Pts with Major Depressive Disorder, Forest Res Inst; Fitzgerald, John, Idiopathic Pulmonary Fibrosis Prospective Outcomes (IPF-PRO) Registry, Boehringer Ingelheim Pharm; Gerber, David, Phase 1/2 Study of BGB324 with Erlotinib for Stage IIIb or IV Non-Small Cell Lung Cancer, Bergenbio AS; Guleserian, Kristine, On-X® Prosthetic Heart Valve – Sizes 17mm Aortic and 23m, ON-X Life Tech Inc; Haley, Barbara, Phase 2 Study of LEE011 with Tamoxifen and Goserelin for Premenopausal Women with Hormone Receptor Positive, HER2-negative, Advanced Breast Cancer, Novartis Pharm Corp; Iannaccone, Susan, 48-Week Study of Eteplirsen in Duchenne Muscular Dystrophy, Sarepta Therapeutics.

Maher, Elizabeth, Phase 1/2 Dose Escalation Study of AG-221 for Adv Solid Tumors and with Angioimmunoblastic T-Cell Lymphoma that Harbor an IDH2 Mutation, Celgene Corp; McKnight, Steven, Study of Existing and New Chemicals that Stimulate the Salvage of NAD from Nicotinamide, Calico Life Sciences; Naina, Harris, Phase 3 Study of IPI-145 with Rituximab for Prev-Treated Follicular Lymphoma, Infinity Pharm Inc; Raskin, Philip, Phase 2 Study of PF-05089771 as Monotherapy and as Add-On to Pregnabalin for Painful Diabetic Peripheral Neuropathy, Pfizer Inc; Schiller, Joan, Phase 2 Study of Co-1686 or Erlotinib for EGFR-Mutant Adv'd Non-Small Cell Lung Cancer, Clovis Oncology Inc; Tannin, Grace, Comparison of VRS-317, a Long-acting Human Growth Hormone, Versartis Inc.