Awards for April 2015

Federal Awards

Adinoff, Bryon, UT Dallas/NIH, Genetic and Environmental Modulators of Brain's Response to Marijuana Cues, $8,567; Ahmad, Zahid, NIH, Molecular Basis of Autosomal Dominant Hypercholesterolemia in a Multiethnic Cohort, $155,250; Baker, Linda, NIH, Prune Belly Syndrome, $368,259; Bezprozvanny, Ilya, NIH, Calcium Channels as Novel Therapeutic Targets for Huntington's Disease, $347,813; Bibb, James, NIH, NMDA Receptor Regulation in Addiction, $313,230; Boothman, David, NIH, Use of Beta-lapachone for Lung Cancer Chemotherapy, $335,140; Borek, Dominika, Mount Sinai Sch of Med/NIH, Therapeutics Targeting Filoviral Interferon-Antagonist, $64,236; Brown, Sherwood, NIH, Attenuation of Corticosteroid-Induced Hippocampal Change - Summer Intern Supplement, $5,076; Buszczak, Michael, NIH, Systematic Characterization of an Aging Stem Cell Niche, $331,075; Cao, Dian, NIH, Autophagy in Metabolic Distress and Cardiac Function: Regulation by the HDAC-FoxO, $132,285; Chook, Yuh Min, NIH, Molecular Biophysics Predoctoral Training Program, $134,038;

Cleaver, Ondine, NIH, Blood Vessel Tubulogenesis: Rasip1-Directed GTPase Signaling and Cell Polarity, $454,636; Crandall, Craig, Dept of Defense, Effects of Thermal Status on Markers of Blood Coagulation during Simulated Hemorrhage, $186,419; Crandall, Craig, American Burn Assoc/Dept of Defense, Effects of a Community Based Exercise Program in Adults with Severe Burns, $63,210; De Lemos, James, National Space Biom Res Inst, Improving Cardiovascular Risk Prediction - Biomarkers and Beyond, $396,901; Deberardinis, Ralph, NIH, Metabolic Regulators of Tumor Cell Growth, $329,925; Deberardinis, Ralph, Univ of Cincinnati/NIH, Metabolic Adaptive Responses in Cancer, $21,723; Elmquist, Joel, NIH, Leptin and Insulin Signaling in SF1 Neurons and Energy Homeostasis, $333,900; Garg, Abhimanyu, NIH, Genetic and Metabolic Basis of Familial Lipodystrophies, $560,704; Gill, Michelle, Univ of Wisconsin/NIH, Mechanistic Study Development for ICAC3 MUPPITS and CoNAC Protocols, $120,957; Goodman, Joel, NIH, Simple Cellular Model for Lipodystrophy, $318,000;

Graff, Jonathan, NIH, Adipocyte Development: Lineage Analysis and Molecular Characterization, $484,500; Greenberg, David, NIH, Novel Gene-Silencing Therapeutics for Multidrug-Resistant Gram-Negative Pathogens, $365,500; Gruchalla, Rebecca, Univ of Wisconsin/NIH, RACR2 (ICAC3), $33,463; Gupta, Rana, NIH, Establishment and Maintenance of Healthy Adipose Tissue in Obesity, $363,375; Hooper, Lora, NIH, Bacterial Regulation of Intestinal Antimicrobial Defense, $345,825; Huang, Jun-Shen, NIH, JAK2 Signaling in Erythropoiesis, $391,537; Idris, Ahamed, Univ of Washington/NIH, ROC Protocols-Fixed Price, $275,002; Idris, Ahamed, Univ of Washington/NIH, ROC Protocols-TXA, $64,000; Idris, Ahamed, Mount Sinai Sch of Med/NIH, Community VOICES 3: Views On Informed Consent in Emergency Situations, $53,864; Idris, Ahamed, NIH, Resuscitation Outcomes Consortium Regional Clinical Center - DFWCRR, $13,515; Jiang, Jin, NIH, Complex Regulation of Ci-Gli Proteins in Hedgehog Signal Transduction, $341,850;

Kane, Alex, Mount Sinai Sch of Med/NIH, Craniosynostosis Network, $13,403; Karp, David, Benaroya Res Inst/NIH, CALIBRATE - Rituximab Plus Cyclophosphamide Followed by Belimumab, $109,618; Kavalali, Ege, NIH, Role of SNARE Interactions in Central Synapse Function, $397,500; Kraus, Lee, NIH, Role of PARP-1 in Hormone-Related Transcription, $411,774; Lehrman, Mark, NIH, The N-Glycosylation Pathway And Signaling By Free Mannose-6-Phosphate, $413,400; Liu, Yi, NIH, Mechanism and Functions of Small RNA Pathways in Neurospora, $286,200; Liu, Zhi-Ping, NIH, Epigenetic Regulation of Cardiac Hypertrophy and Heart Failure, $391,537; Luo, Xuelian, NIH, Activation Mechanism of the Tumor-Suppressing MST-LATS Kinase Cascade, $302,100; Macdonald, Raymond, NIH, Transcriptional Regulators of the Exocrine Pancreatic Phenotype, $488,561; Maher, Elizabeth, NIH, Defining Metabolic Phenotype of Low Grade Gliomas in Vivo, $329,925; Mani, Ram, NIH, Tracing the Origins of Chromosomal Translocations in Prostate Cancer, $249,000;

Merritt, Matthew, NIH, Hyperpolarized 13C Imaging for Studying Beta-Oxidative and Anaplerotic Pathways, $198,750; Minna, John (Fellow A. Augustyn), NIH, Defining Molecularly Distinct Subtype of Non Small Cell Lung Cancer, $37,020; Mootha, Venkateswara, NIH, Genetics and Genomics of Fuchs Endothelial Corneal Dystrophy, $311,640; O'Suilleabhain, Padraig, Massachusetts Gen Hosp/NIH, Coenzyme Q10 in Huntington's Disease, $4,870; Pasare, Chandrashekhar, NIH, Role of Microenvironmental Cues in CD8 T Cell Activation and Memory Generation, $242,250; Peng, Fangyu, NIH, Altered Copper Metabolism as Theranostic Biomarker in Alzheimer's Disease, $201,952; Petroll, Matthew, NIH, Assessment of Corneal Fibroblast Biomechanical Behavior, $389,550; Pfeiffer, Julie, NIH, Genetics of Bacteria-Mediated Viral Co-Infection, $242,250; Phillips, Margaret, NIH, Polyamine and Trypanothione Metabolism in Trypanosoma Brucei-Diversity Supplement, $39,096; Ready, Joseph, Mount Sinai Sch of Med/NIH, Therapeutics Targeting Filoviral Interferon-Antagonist and Replication Functions, $366,771;

Robertson, Danielle, NIH, Effects of Systemic Disease on Corneal Epithelial Pathophysiology, $403,750; Rohatgi, Anand, NIH, Moving Beyond HDL Cholesterol, HDL Function as a Coronary Disease Biomarker, $117,720; Rosen, Michael, NIH, Structural Study of GTPase Regulators and Effectors, $319,237; Saha, Debabrata, NIH, Role of DAB2IP in Prostate Cancer Patients Treated with Radiation Therapy, $207,495; Schaffer, Joseph, RTI Intl/NIH, NICHD Pelvic Floor Disorders Network - Capitation Funding, $833; Scherer, Philipp, NIH, White Adipose Tissue Physiology, Mitochondrial Function and Adiponectin, $464,280; Schiller, Joan, SRI Intl/NIH, Tumor Targeting Peptides, $40,303; Schmid, Sandra, NIH, Mechanisms Regulating Clathrin-Mediated Endocytosis (MPI), $417,068; Schneider, Jay, NIH, Microenvironmental Control of Progenitors in Organ Dysfunction and Repair (MPI), $1,241,255; Sherry, Dean, NIH, Metabolism in the Heart by NMR, $391,537; Stull, James, NIH, Signal Transduction Mechanisms to Myosin Phosphatase, $33,787;

Tamminga, Carol, NIH, Basic Science Training Program in Neurobiology of Mental Illness, $272,366; Timaran, Carlos, Univ of Med & Dentistry of NJ/NIH, Carotid Revascularization Endarterectomy vs. Stent Trial (CREST), $12,600; Winter, Sebastian, NIH, Central Metabolism of Salmonella in the Inflamed Gut, $403,750; Wolf, Steven, UT Medical Branch/Dept of Defense, Identification and Validation for Established and Novel Biomarkers for Infections, $69,291; Wright, Woodring, NIH, Gene Expression in Aging and Development, $381,079; Wyckoff, Myra, RTI Intl/NIH, NICHD Neonatal Research Network Capitation Funding, $35,657; Zhang, Chun-Li, NIH, In Vivo Reprogramming of Glial Fate for Spinal Cord Repair, $347,813; Zhao, Dawen, NIH, Convertible MRI Contrast Signaling Delivery and Release of Antiglioma Nano-Drug, $369,431; Zhu, Hao, NIH, Reactivation of Embryonic Growth Programs in Liver Cancer, $369,431.

Nonfederal Awards

Abrams, John, Welch Fdn, Apoptosome Caspase Control by Tango7, $65,000; Alto, Neal, Welch Fdn, Post-Translational Modification of Host Enzymes by Bacterial Effector Proteins, $80,000; Anderson, Larry, Multiple Myeloma Res Fdn, Prospective, Longitudinal, Observational Study in Newly Diagnosed Multiple Myeloma (MM) Patients, $107,455; Chen, Chuo, Welch Fdn, Development of Anticancer Immunotherapeutic Agents, $65,000; Danuser, Gaudenz (Fellow P. Roudot), Human Frontier Science Prgm, The Cortex Behind 3D Migration: Actin, Myosin and Adhesion Dynamics Studied by 3D, $51,720; D'Orso, Ivan, Welch Fdn, Cooperative Assembly of HIV Transcription Elongation Complexes, $65,000; Gardner, Lisa (Fellow M. Pearson), Native American Res Cntr for Hlth, NARCH - Pearson, M., $28,000; Goldsmith, Elizabeth, Welch Fdn, Kinetics and Chemistry of the p38 MAPK Cascade, $65,000; Henne, William, Welch Fdn, Novel Pathways of ER-Endolysosomal Inter-Organelle Communication, $65,000; Hooper, Lora, Welch Fdn, Engineering Antibacterial Lectins for Spec. Targeting of Antibiotic-Res. Bacteria, $65,000;

Jain, Raksha, Seattle Children’s Res Inst/Cystic Fibrosis Fdn, Early Intervention in Pulmonary Exacerbation, $21,084; Jewell, Jenna, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Member, $500,000; Kliewer, Steven, Welch Fdn, Mechanisms Underlying the Secretory Actions of FGF21 in Exocrine Pancreas, $110,000; Li, Bing, Welch Fdn, Mechanisms of Histone H3 Lysine-to-Methionine Mediated Chromatin Misregulation, $65,000; Liou, Jen, Welch Fdn, Novel Imaging Probes for Investigating ER Plasma Membrane Contact Sites, $65,000; Liu, Xin, Welch Fdn, Structural Basis and Chemical Modulation, $65,000; Liu, Yi, Welch Fdn, Biochemical Analysis of RNA Interference Pathways, $110,000; Mangelsdorf, David, Welch Fdn, Ligand Binding Properties of Nematode Orphan Nuclear Receptors, $110,000; Martinez, Elisabeth, Welch Fdn, Small Molecule Inhibitors Selectively Targeting Malaria Epigenetic Enzymes, $65,000; Morrison, Sean (Fellow E. Piskounova), Helen Hays Whitney Fdn, Role of Lyn Kinase on Melanoma Metastasis, $50,500;

Nijhawan, Deepak, Welch Fdn, Expanding the Druggable Genome, $65,000; Nwariaku, Ohwofiemu, Delta State Government, Emmanuel Uduaghan Kidney Diseases and Urology Educational Support Award, $400,000; O'Donnell-Mendell, Kathryn, Welch Fdn, Dissecting Novel Mechanisms of Lung Cancer Pathogenesis, $65,000; Olson, Eric, Fondation Leducq, Programming the Failing Heart To a Regenerative State, $164,567; Orth, Kim, Welch Fdn, Using Chemistry and Genetics with VopQ to Decipher Vacuolar Fusion Events, $80,000; Radhakrishnan, Arun, Welch Fdn, Molecular Mechanisms of Cholesterol Sensors in Human Cells, $65,000; Ranganathan, Rama, Welch Fdn, Principles of Allosteric Control in Proteins, $110,000; Rosenberg, Roger, Dallas Fdn, DNA Aß42 Vaccine to Prevent Alzheimer’s Disease, $25,000; Shay, Jerry (Fellow J. Peters-Hall), Cystic Fibrosis Fdn, Telomerase Immortalized HBE Cells to Study Primary Defects of Mutant CFTR, $46,250; Tagliabracci, Vincent, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Member, $500,000;

Tu, Benjamin, Welch Fdn, Selective Regulation of Metabolism by a Conserved Inhibitor of TORC1, $110,000; Uyeda, Kosaku, Welch Fdn, Biochemical Mechanism of Glucose Sensing & Regulation, $65,000; Yu, Yonghao, American Cancer Soc, Overcoming Rapamycin Resistance for the Treatment of Bladder Cancer, $198,000; Yu, Yonghao, Welch Fdn, Large-Scale Isolation and Identification of Poly-ADP-Rib, $80,000; Zhang, Chun-Li, Welch Fdn, Chemical Regulation of Human Motor Neurons, $80,000.

Industry Sponsored Awards, dollar amounts not available

Anderson, Larry, Phase 3 Study of Ibrutinib with Rituximab in Sjbs with Prev Trted Waldenstroms Macroglobulinemia, Pharmacyclics Inc; Aquino, Victor, Phase II Study of Anti-CD22 Recombinant Immunotoxin Moxetumomab Pasudotox in Children with B-lineage Acute Lymphoblastic Leukemia, Natl Bone Marrow Donor Prgm; Brugarolas, James, Phase 3 Study of Nivolumab with Ipilimumab vs. Sunitinib Monotherapy in Sbjs with Prev Untreated Advanced or Metastatic Renal Cell Carcinoma, Bristol-Myers Squibb; Carr, Bruce, Phase 3 Trial of TX-004HR in Postmenopausal Women with Symptoms of Vulvar and Vaginal Atrophy, Therapeuticsmd Inc; Copley, Lawson, Study of Daptomycin vs. Active Comparator in Ped Sbjs with Acute Hematogenous Osteomyelitis due to Gram-Positive Organisms, Cubist Pharma Inc; Deleon, Jean, Use of Skin IQ Microclimate Manager for Prevention of Pressure Ulcer Development, Arjohuntleigh Inc;

Gebreyohanns, Mehari, Study to Prevent Major Vascular Events with Ticagrelor Compared to Aspirin in Pts with Acute Ischemic Stroke or TIA, Astrazeneca Pharma; Greenberg, David, Antibacterial PPMO Development, Sarepta Therapeutics; Haley, Barbara, Phase 3 Study of Veliparib and Carboplatin in Sjbs w/ Early Stage Triple Negative Breast Cancer, Abbvie Inc; Haller, Ronald, Phase 2 Study of RTA 408 for Mitochrondrial Myopathy, Reata Pharma Inc; Holland, William, Tissue-Specific Improvements in Glucose uptake and Efflux, Remd Biotherapeutics; Kalva, Sanjeeva, SENTRY: Clinical Study of Novate Sentry Bioconvertible Inferior Vena Cava Filter, Novae Medical;

Laetsch, Theodore, Phase 1b/2 Study of Carfilzomib with Dexamethasone, Mitoxantrone, PEG-asparaginase, and Vincristine (UK R3 Induction Backbone) in Children with Relapsed or Refractory Acute Lymphoblastic Leukemia, Onyx Pharma; Lavery, Lawrence, 12-Week Study of NPWT PRO vs. KCI ULTA NPWT for Chronic Diabetic Foot Ulcers, Cardinal Health; Lavery, Lawrence, Continuous Diffusion of Oxygen Treatment for Healing of Diabetic Foot Ulcers, EO2 Concepts; Lavery, Lawrence, Phase 2 Study of Intramuscular Injection of Human Placenta-Derived Cells in Sbjs with Diabetic Foot Ulcer with Peripheral Arterial Disease, Celgene Corp; Pawlowski, Karen, Ototoxic potential of the Middle Ear Application of Bril, Cellceutix Corp; Pillai, Anil, Phase 3 Trial of TheraSphere in Pts with Metastatic Colorectal Carcinoma to the Liver who have Failed First Line Chemotherapy, Biocompatibles UK Ltd;

Rambally, Siayareh, Phase 3 Study of Oral Pacritinib in Pts with Thrombocytopenia and Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis, CTI Biopharma Corp; Reimold, Andreas, Phase 3B/4 Study of Tofacitinib Compared to TNF Inhibitor in Sbjs with Rheumatoid Arthritis, Pfizer Inc; Scherer, Philipp, Impact of KDT 501 on the Function of TLR-4 in Adipocytes, Kindex Pharma; Seemann, Joachim, Test Feasibility & Assess Retention of Magnelles, Bell Biosystems Inc; Szmuk, Peter, Eval of Tapentadol Oral Solution for Post-Op Acute Pain Requiring Opioid Trtmt in Ped Sbjs under 18 yrs, Janssen Res & Dev LLC; Tiwana, Gurbir, Open Versus Closed Treatment of Subcondylar Fractures, Biomet Microfixation Inc; White, Michael, Biomarker-driven Intervention Target Discovery, Takeda Pharma Intl Inc.