Awards for February 2015

Federal Awards

Alto, Neal, NIH, Type III Effector Regulation of Host Signal Transduction Systems, $217,172; Brekken, Rolf, NIH, Exploitation of RAS Signaling to Develop Therapy & Detection Strategies for PDA (MPI), $440,978; Brown, Edson, NIH, Citicoline for Alcohol Dependence, $221,705; Brown, Edson, NIH, Attenuation of Corticosteroid-Induced Hippocampal Changes, $25,847; Brugarolas, James, NIH, Evaluation of BAP1 Tumor Suppressor Gene in Renal Cell Carcinoma, $329,925; Burgess, Shawn, NIH, Factors Controlling Metabolic Flux in Liver by NMR Isotopomer Analysis, $34,583; Burma, Sandeep, NIH, Molecular Mechanisms of GBM Radioresistance and Strategies for Radiosensitization, $32,993;

Burstein, Ezra, NIH, Control of NF-kB and Inflammation by COMMD Proteins, $345,825; Cadeddu, Jeffrey, XIGEN LLC/NIH, Tethered Lightfield 3D Camera for Advanced Minimally Invasive Surgeries, $35,775; Carroll, Thomas, Georgia Regents Univ/NIH, A Screen for Transcription Factors that can Promote Transdifferentiation, $60,000; Casey, Brian, George Washington Univ/NIH, MEFU NICHD Network, $23,564; Chen, Christopher, UT Arlington/Dept of Defense, Treating Post-Traumatic Osteoarthritis by Promoting Autologous Stem Cell-Mediated Cartilage Regeneration, $64,858; Chen, Chuo, NIH, Asymmetric Synthesis of Biologically Active Marine Natural Products, $29,982;

Chiang, Cheng-Ming, NIH, E2-Cellular Complexes in HPV Chromatin Transcription, $395,910; Chin, Kelly, NIH, Serotonin Transporter in Pulmonary Arterial Hypertension, $128,589; Choy, Hak, NIH, National Particle Therapy Research Center (NPTRC), $507,393; Crandall, Craig, NIH, Exercise in Burn Survivors, $563,866; Deberardinis, Ralph (Fellow L. Boroughs), NIH, Connections Between Cell Metabolism and Signaling in Lung Cancer, $52,406; Garcia, Christine, NIH, Mutant Surfactant Induced TGF-beta Secretion in Lung Fibrosis, $44,737; Greenberg, David, NIH, Circumventing Antibiotic Resistance with Novel Gene-Silencing Therapeutics (R21/R33), $199,973; Haley, Robert, Georgia State Univ/Dept of Defense, Abnormalities in Human Brain, $10,543;

Hedayati, Susan, NIH, Randomized Trial of Sertraline Treatment of Depression in Chronic Kidney Disease, $345,825; Hiesinger, Peter, NIH, Intracellular Trafficking and Neuronal Connectivity in Visual System, $31,800; Hooper, Lora, NIH, Integrative Immunology Training Program, $384,554; Hsieh, Jenny, Emory Univ/NIH, Regulations of Epileptogenesis by Transcription Repressor; REST, $68,000; Jiang, Huaqi, NIH, Notch Signaling and fkh Cooperate to Maintain Intestinal Stem Cells in Drosophila, $363,375;

Jiang, Jin, NIH, Genetic Control of Drosophila Intestine Stem Cell Self-Renewal and Proliferation, $302,100; Jiang, Steve, Massachusetts General Hosp/NIH, Development and Validation of Ultra-Fast Dose Calculation for Proton Therapy, $74,999; Jiang, Steve, NIH, Low Dose Cone Beam CT for Image Guided Adaptive Radiotherapy, $2,946; Jiang, Youxing, NIH, Molecular Mechanisms of Cation Channel Selectivity, $289,380; Kliewer, Steven, NIH, Tissue-Specific Mechanism of Action of the Metabolic Hormones FGF19 and FGF21, $347,225; Konopka, Genevieve (Fellow M. Fontenot), NIH, Neocortical Regulation of Circadian Rhythms, $30,812;

Kurti, Laszlo, Natl Science Fdn, CAREER: SusChEM: Exploiting the Versatile N-O Bond, $135,000; Kutz, Joe Walter, Nationwide Children’s Hosp/NIH, Virtual Temporal Bone, $8,500; Madden, Christopher, Univ of California, San Fran/NIH, Transforming Research and Clinical Knowledge in Traumatic Brain Injury-TRACK-TBI, $202,663; Mammen, Pradeep, NIH, Cytoglobin: Stress-Responsive Hemoprotein Modulating Cardiomyocyte Survival, $391,537; Mangelsdorf, David (Fellow K. Colbert), NIH, Elucidation of the FGF21-Bmp8b Axis in the Regulation of Energy Balance, $56,042;

McKnight, Steven, NIH, Targeting Acetyl-CoA Metabolism for the Discovery of New Anti-Cancer Therapeutics (MPI), $475,351; Mendelson, Carole, NIH, Initiation of Human Labor: Prevention of Prematurity, $1,278,373; Mendelson, Carole, NIH, Cellular Mechanisms in Induction of Aromatase, $401,095; Miller, David, NRG Oncology Fdn/NIH, NRG Oncology Network Group Operations Center, $15,000; Morrison, Sean (Fellow R. Burgess), NIH, Role of Proline Dehydrogenase in Hematopoietic Stem Cell Function, $54,194;

Niederkorn, Jerry, NIH, Transplant and Tumor Rejection Processes Within the Eye, $389,550; Niederkorn, Jerry, NIH, Immunological Modulation of Ocular Tumor Metastases, $28,218; Olson, Eric, NIH, Deciphering Regulatory Circuit for Myocardial Metabolism and Energy Homeostasis, $47,173; Olson, Eric, NIH, Deciphering Regulatory Circuit for Myocardial Metabolism and Energy Homeostasis - Diversity Supplement, $7,568; Orth-Taussig, Kimberly, NIH, Proteostasis, AMPylation and the Unfolding Protein Response (UPR), $310,888; Pearson, Gray, NIH, Investigating Breast Cancer Collective Invasion, $329,925;

Phelps, Katherine, NIH, SEM for UT Southwestern EM Core Facility, $306,457; Raj, Ganesh, Univ of Washington/Dept of Defense, Targeting the Aberrant Androgen Receptor in Advanced Treatment Resistant Prostate Cancer, $526,029; Rice, Luke, Natl Science Fdn, 2015 REU Supplement to MCB - 1054947, $4,150; Rodriguez-Baez, Norberto, Johns Hopkins Univ/NIH, Effect of HBV DNA Methlyation and the Mutant 1762T/1764A, $208,191; Rosenberg, Roger, Univ of Washington/NIH, National Alzheimer's Coordinating Center, $26,000; Sambandam, Kamalanathan, Univ of Pennsylvania/NIH, Penn PCC in CureGN, $23,304; Schaffer, Joseph, RTI Internatl/NIH, NICHD Pelvic Floor Disorders Network, $11,087;

Schmid, Sandra, NIH, The Clathrin Coated Vesicle Cycle, $452,185; Seikaly, Mouin, Children’s Mercy Hosp/NIH, Chronic Kidney Disease in Children-Prospective Cohort Study (CKID), $45,280; Self, David, Mount Sinai School of Med/NIH, Molecular Neurobiology of Drug Addiction, $261,301; Shen, Yu-Min, St. Jude Children’s Res Hosp/NIH, AGT4HB-Study of Adeno-Assoc Viral Vector (scAAV2/8-LP1-hFIXco) for Gene Transfer in Sbjs with Hemophilia B, $15,650; Singal, Amit, Kaiser Fdn Res Inst/NIH, CRN4: Cancer Research Resources & Collaboration in Integrated Health Care Systems, $27,744; Smith, Dean, NIH, Molecular Basis of Pheromone-Induced Behaviors in Drosophila, $393,525; Snell, William, NIH, Cell Surface Recognition and Cell Interactions, $363,375; Terman, Jonathan, NIH, Molecular Mechanisms of Semaphorin/Plexin-Mediated Cytoskeletal Reorganization, $347,813;

Timmerman, Robert, NRG Oncology Fdn/NIH, NRG Oncology Studies, $308,172; Whitehurst, Angelique, NIH, Mechanistic Elaboration of Fragility in the Cancer Cell Mitotic Spindle, $32,166; Wright, Woodring, NIH, Manipulating Telomerase Alternative Splicing for Cancer Therapy, $32,993; Wyckoff, Myra, RTI Internatl/NIH, NICHD Neonatal Research Network, $26,591; Xu, Jian, NIH, Mechanistic Roles of BCL11A in Globin Switching and Fetal Hemoglobin Silencing, $91,991; Xu, Jian, NIH, Characterizing the Role of BCL11A in Hematopoietic Development and Functions, $34,288; Zhang, Hong, NIH, Molecular Interactions of Mammalian Circadian Clock Proteins (MPI), $302,100. 

Nonfederal Awards

Chen, Zhijian, CPRIT, Harnessing the Cytosolic DNA Sensing Pathway for Cancer Immunotherapy, $296,386; Chook, Yuh Min, CPRIT, Mechanisms of Nuclear Import and Export in Cancer- Renewal - 1, $300,000; Davis, Laurie, Alliance for Lupus Res, TREM-1 in Lupus Nephritis, $186,103; Fujikawa, Teppei, American Heart Assoc Natl Ctr, Hypothalamic Pathway Mediates Anti-Type 1 Diabetes Actions of Leptin, $77,000; Hedayati, Susan, Univ of Washington/PCORI, Treatment Options for Depression in Patients Undergoing Hemodialysis, $158,540; Hill, Joseph (Fellow G. Cho), American Heart Assoc SW, Reperfusion Injury Rescue by Tat-Beclin-dependent Regulation of Cardiomyocyte Autophagy, $51,092; Husain, Mustafa, Univ of New South Wales, Controlled Trial of Transcranial Direct Current Stimulation as Treatment for Unipolar and Bipolar Depression, $5,000; Jain, Raksha, Seattle Children’s Res Inst/Cystic Fibrosis Fdn, G551D Observational Study, $3,483; Jiang, Steve, CPRIT, Translating Online Adaptive Radiotherapy from Lab to Clinical Practice, $296,642; Karp, David (Fellow C. Arriens), Mallinckrodt Pharmaceuticals, Research Fellowship Award Program, $50,000;

Lavery, Lawrence, American Diabetes Asoc, Negative Pressure Wound Therapy as a Drug Delivery System, $178,936; Leavey, Patrick, CPRIT, Using Imaging and Computational Tools to Improve Risk Stratification in Children with Bone Cancer, $321,569; Mahendroo, Mala, March of Dimes Fdn, Insights into Diversity of Cervical Ripening Processes in Term and Preterm Birth, $100,000; Malloy, Craig, CPRIT, TAMU-UT Southwestern Partnership for Breast Imaging and Spectroscopy, $299,753; McFadden, David, CPRIT, Deciphering Genetic and Epigenetic Mechanisms - Recruitment Grant, $228,941; Medin, Paul, CPRIT, Peripheral Nerve Tolerance to Single-Session Stereotactic Irradiation, $298,941; Parada, Luis, CPRIT, Functional and Structural Characterization of a Small Chemical Compound that Arrests Glioma Stem Cell Growth with High Activity and Specificity, $299,991; Potts, Patrick, Fdn for Prader-Willi Res, Linking the Cellular Function of MAGE-L2 to its Role in PWS, $108,000; Powell, Craig, Baylor College of Med/Autism Speaks, Identifying Biomarkers of GI Morbidity in ASD, $127,655;

Roberts, Todd, Brain & Behavior Res Fdn/NARSAD, Testing the Behavioral Significance of Corollary Discharge Pathways and Their Contribution to Schizophrenia, $30,000; Schwartz, David, CPRIT, Phase I Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Advanced Laryngeal Cancer, $298,930; Tiwana, Gurbir (Fellow N. Panchal), Depuy Biologics, 15th Annual Symposium Selected Topics in Orthognathic Surgery, $800; Wakeland, Edward, Alliance for Lupus Res, Identifying Functional Variants that Underlie SLE Susceptibility, $190,119; Yan, Nan, Alliance for Lupus Res, Glycans and Glycosylation Defects as Novel Targets in Lupus, $188,416; Ye, Jin, Welch Fdn, Saturated Fatty Acid-Induced Lipotoxicity, $60,000; Zhang, Chun-Li, Ellison Medical Fdn, Genomics Approach to Understanding Neural Stem Cell Aging, $100,000; Zigman, Jeffrey, Fdn for Prader-Willi Res, Ghrelin: Is it Detrimental, Beneficial, or Inconsequential in Prader-Willi Syndrome, $108,000.

Industry Sponsored Awards

(Dollar amounts not available)

Ahmad, Zahid, R1500: Study of Safety, Tolerability and Bioeffect of Subcutaneously or Intravenously, Regeneron Pharm Inc; De Lemos, James, ARCHITECT hsTnI assay study (DHS samp-FDA Submission), Abbott Labs; Kho, Kimberly Anne, Validation of Umbilical Model for Laparoscopic Curriculum for Laparoscopic Task Training, Applied Medical; Nasir, Dawood, Effect of pre-operative Pregabalin and Ketamine to prevent development of phantom pain in pts with lower extremity amputation, Pfizer Inc; Novakovic, Roberta, Adjunctive Neurovascular Support for Wide-neck aneurysm, Pulsar Vascular Inc; Okuda, Darin, Assessment of Tecfidera in extending the time to a first attach in radiologically isolated syndrome (RIS): ARISE, Biogen Idec Inc;

Patel, Neepa, ADS-51-2 Extd Release Capsules for Levodopa Induced Dyskinesia in Parkinson's Disease Pts, Adams Pharm Inc; Reimold, Andreas, Phase 3 Study of CNTO 136 in rheumatoid Arthritis Sbjs completing Treatment in CNTO136ARA3002 and CNTO136ARA3003, Parexel Intl; Robertson, William, Transtibial Femoral Tunnel Reaming with Mono-Fluted Ream, Conmed Corp; Sanghavi, Rinarani, Study of Lubiprostone in Ped Sbjs 6-18 Yrs with Functional Constipation, Sucampo Pharm Inc; Sawant, Amit, Multimodality Patient-Specific Motion Models, Vision RT Limited;

Schiller, Joan, Phase 1/2 Study of Oral CO-1686 in Pts with Prev Treated Mutant EGFR Non-Small Cell Lung Cancer, PRA Health Sciences; Schiller, Joan, Phase 3 Trial Comparing Veliparib Plus Carboplatin and Paclitaxel vs. Standard Chemotherapy in Sbjs Receiving First Cytotoxic Chemo for Metastatic or Adv'd Non-Squamous Mon-Small Cell Lung Cancer who are Current or Former Smokers, Abbvie Inc; Story, Michael, Preclinical evaluation of GC4419 (Part II), Galera Therapeutics Ltd; Sumpter, Kathryn, Study of Human Plasma-Derived, Alpha-Proteinase Inhibitor in Children and Adults with Recent-Onset Type 1 Diabetes Mellitus, Grifols Worldwide Oper Ltd; Szmuk, Peter, Study of Hydromorphone Hydrochloride Extd-Release Tablets in Opioid-Tolerant Pediatric Sbjs with Chronic Pain, Quintiles Inc; Ufret-Vincenty, Rafael, Phase 3 Study of Lampalizumab Admin IV to Pts with Geographic Atrophy Secondary to Age-Related Macular Degeneration, Genentech Inc; Zeltser, Ilana, Hypertrophic Cardiomyopathy in Children: Age Specific Risk Stratification for Sudden Death, Children’s Hosp of Philadelphia.