Biomedical Engineering Faculty

Program Chair

Matthew Petroll, Ph.D.
Matthew Petroll, Ph.D.

Professor

Training Tracks: Biomaterials, Mechanics and Tissue Engineering; Biomedical and Molecular Imaging

Research Interests: Cell motility and mechanics, corneal repair and regeneration, in vivo confocal imaging

Faculty

Asaithamby Aroumougame, Ph.D.

Associate Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Immunotherapy and radiotherapy in cancer prevention and treatment; premature aging and carcinogenesis; DNA damage response signaling in heart development

Asaithamby Aroumougame
Spencer Bowen, Ph.D.

Assistant Professor

Research Interests: Development of hybrid positron emission tomography (PET) (e.g. PET-CT and PET-MR) tools to enable precision imaging for the care and study of oncology, neurology, and cardiology patients.

Spencer Bowen, Ph.D.
Shawn C. Burgess, Ph.D.

Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: NMR spectroscopy and mass spectroscopy in conjunction with the application of stable isotope tracers to study metabolic function

Shawn Burgess, Ph.D.
David Busch, Ph.D.

Assistant Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Developing non- and minimally invasive optical tools to monitor deep tissues in health and disease, as well as throughout therapy

David Busch, Ph.D.
Thomas Carroll, Ph.D.

Professor

Training Track: Biomaterials, Mechanics and Tissue Engineering

Research Interests: Cancer, cell polarity, developmental biology, morphogenesis, stem/progenitor cells, tissue engineering and regeneration

Thomas Carroll, Ph.D.
Jonathan Cheng, M.D.

Professor

Training Track: Biomaterials, Mechanics and Tissue Engineering

Research Interests: Nerve regeneration; long nerve gap repair; nerve-machine interface

Jonathan Cheng, M.D.
Changho Choi, Ph.D.

Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: In vivo 1H and 13C MR spectroscopy; MRS applications in brain tumors and neuropsychiatric diseases; MR physics and MR method development

Changho Choi, Ph.D.
Rajiv Chopra, Ph.D.

Associate Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Development of MR-guided high-intensity focused ultrasound for preclinical and clinical imaging

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Ian Corbin, Ph.D.

Associate Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Molecular imaging techniques and nanomedicine-technology development to better understand and characterize liver disease

Ian Corbin, Ph.D.
Gaudenz Danuser, Ph.D.

Professor

Research Interests: Regulation of cell morphogenesis during metastasis; roles of mechanics in cell survival and drug resistance

Gaudenz Danuser, Ph.D.
Caroline de Gracia Lux, Ph.D.

Assistant Professor

Training Track: Molecular and Translational Nanomedicine

Research Interests: Ultrasound contrast agent, perfluorocarbon emulsions, development of new ultrasound-based strategies for early detection and treatment of diseases

Caroline de Gracia Lux, Ph.D.
Reto Fiolka, Ph.D.

Assistant Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: The long-term goal of our lab’s research is to develop and implement imaging technologies that provide unprecedented insight into cancer biology.

Reto Fiolka, Ph.D.
Thomas Floyd, M.D.

Professor

Floyd Lab

Training Track: Biomedical and Molecular Imaging

Research Interests: Prevention and early detection of neurological injury associated with surgery

Thomas Floyd, M.D.
Yang-Xin Fu, M.D., Ph.D..

Professor

Training Track: Molecular and Translational Nanomedicine

Research Interests: Cancer microenvironment, tumor targeted immunotherapy, antibody engineering, anti-cancer treatment-induced immune responses

Yang-Xin Fu, M.D., Ph.D., Ph.D.
Jinming Gao, Ph.D.

Professor

Training Tracks: Molecular and Translational Nanomedicine; Biomedical and Molecular Imaging

Research Interests: Activatable optical/MRI imaging probes to study tumor metabolism and theranostic nanomedicine for cancer-targeted drug therapy

Jinming Gao, Ph.D.
Gerald Greil, M.D., Ph.D.

Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Evaluate the use of newly designed biodegradable stints to treat pulmonary artery stenosis

Gerald Greil, M.D., Ph.D.
Xuejun Gu, Ph.D.

Associate Professor

Training Track: Medical Physics

Research Interests: Image processing in radiation therapy; deformable-image registration; radiation-dose calculations; robotic control for patient positioning

Xuejun Gu, Ph.D.
Daniel Heitjan, Ph.D.

Professor

Research Interests: Statistical analysis and rational design of cellular systems; evolutionary design of the bacterial flagellum

Daniel Heitjan, Ph.D.
Anke Henning, Ph.D.

Professor

Research Interests: Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; ultra-high field MRI; hardware; RF coils; B0 shimming; sequence development; data analysis

Anke Henning, Ph.D.
Gary Hon, Ph.D.

Assistant Professor

Research Interests: Developing (epi)genomic/bioinformatic tools to assess and predict the functions of regulatory elements, epigenetic biomarkers of disease state, epigenetics in development and disease, global regulation of mammalian gene expression, non-coding genome function

Gary Hon, Ph.D.
Connie Hsia, M.D.

Professor

Training Tracks: Biomedical and Molecular Imaging; Biomaterials, Mechanics and Tissue Engineering

Research Interests: Heart-lung interaction; lung morphometry; structure-function correlation of lung growth

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Khuloud Jaqaman, Ph.D.

Assistant Professor

Research Interests: Quantitative single-molecule imaging of receptor organization and signaling; linking molecular and cellular behavior across multiple scales; computational image analysis and data multiplexing

Khuloud Jaqaman, Ph.D.
Xun Jia, Ph.D.

Professor

Training Tracks: Biomedical and Molecular Imaging; Medical Physics

Research Interests: High-performance computing for radiation therapy and medical imaging; radiation-dose calculation; Monte Carlo simulation; 3D/4D cone beam CT reconstruction; image-guided radiation therapy

Xun Jia, Ph.D.
Steve Jiang, Ph.D.

Professor

Training Tracks: Biomedical and Molecular Imaging; Medical Physics

Research Interests: Cloud and GPU-based high-performance computing in medical physics and imaging; automatic radiotherapy treatment planning; adaptive radiotherapy; image-guided radiotherapy; low-dose and dynamic-cone-beam CT

Steve Jiang, Ph.D.
Lukasz Joachimiak, Ph.D.

Assistant Professor

Research Interests: Molecular recognition in protein folding, chaperone structural biology and neurodegeneration

Lukasz Joachimiak, Ph.D.
Daehwan Kim, Ph.D.

Assistant Professor

Research Interests: DNA, RNA, and bisulfite sequence alignment, graph alignment to population of genomes and genotyping, personalized medicine with a focus on cancer diagnosis

Daehwan Kim, Ph.D.
Zoltan Kovacs, Ph.D.

Associate Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Generation and application of hyperpolarized13C-labeled compounds and89Y-complexes for MRI/Radiopharmaceutical applications

Zoltan Kovacs, Ph.D.
Bo Li, Ph.D.

Assistant Professor

Research Interests: Computational cancer immunology, tumor-immune interaction and high-throughput profiling of immune receptor repertoire

Bo Li, Ph.D.
Milo Lin, Ph.D.

Assistant Professor

Research Interests: Theoretical and computational approaches to predict protein folding and aggregation; evolutionary dynamics

Milo Lin, Ph.D.
Weiguo Lu, Ph.D.

Associate Professor

Research Interests: Adaptive radiation therapy; treatment-plan optimization; radiation-dose calculations

Weiguo Lu, Ph.D.
Jacques Lux, Ph.D.

Assistant Professor

Training Tracks: Molecular and Translational Nanomedicine; Biomedical and Molecular Imaging

Research Interests: Bioresponsive nanomaterials for in vivo detection and therapy; targeted and activatable ultrasound (US) agents for the detection of inflammation and cancer

Jacques Lux, Ph.D.
Ananth Madhuranthakam, Ph.D.

Assistant Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Development of novel MR-imaging techniques for whole-body cancer screening and staging

nanth Madhuranthakam, Ph.D.
Mala Mahendroo, Ph.D.

Professor

Training Track: Biomedical and Molecular Imaging Track

Research Interests: Parturition (the process of labor); cervical ripening; male and female reproductive biology

Mala Mahendroo, Ph.D.
Joseph Maldjian, Ph.D.

Professor

Training Track: Biomedical and Molecular Imaging Track

Research Interests: Deep Learning applications in neuroimaging including brain tumor molecular marker prediction, Traumatic Brain Injury, MEG, MRI, fMRI

Joseph Maldjian, Ph.D.
Craig Malloy, M.D.

Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: 13C MRS methods for measuring cardiac intermediary-metabolism flux and function analysis/neurotransmitter metabolism of human brain

Craig Malloy, M.D.
Ralph P. Mason, Ph.D.

Professor

Training Tracks: Molecular and Translational Nanomedicine; Biomedical and Molecular Imaging

Research Interests: Tumor pathophysiology and MR assessment of prognostic biomarkers/hypoxia and pH

Ralph Mason, Ph.D.
Albert Montillo, Ph.D.

Assistant Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Developing state-of-the-art machine-learning approaches to extract radiological imaging and imaging-genomic biomarkers for individualized prognostics in neuroscience and oncological applications

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Dan Nguyen, Ph.D.

Assistant Professor

Training Track: Medical Physics

Research Interests: Radiation therapy treatment planning, optimization techniques and algorithms, artificial intelligence technology development and applications
Dan Nguyen, Ph.D.
Zbyszek Otwinowski, Ph.D.

Professor

Research Interests: Methods development for cryo-electron microscopy, X-ray crystallography, and next-generation sequencing; Structural studies of macromolecules with X-ray crystallography and cryo-EM single particle reconstruction; Higher-order structure of eukaryotic chromatin.

Zbyszek Otwinowski, Ph.D.
Orhan K. Oz, M.D., Ph.D.

Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Application of structural (X-ray, CT, and MR) and functional (SPECT and PET) imaging methods to quantify changes in bone mass and metabolism induced by metabolic bone diseases; in vivo assessment of beta-cell mass and function by novel probes; novel PET and SPECT probe development for bone cells

Orhan Oz, M.D.
Jae Mo Park, Ph.D.

Assistant Professor

Training Track: Biomedical and Molecular Imaging Track

Research Interests: Development of noninvasive molecular imaging tools to elucidate in vivo metabolism

Jae Mo Park, Ph.D.
Ivan Pedrosa, M.D.

Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Development of novel MRI techniques for improved diagnosis of abdominal/pelvic diseases and noninvasive in vivo assessment of physiology and response to therapy in tumors

Ivan Pedrosa, M.D.
Matthias Peltz, M.D.

Associate Professor

Training Track: Biomaterials, Mechanics and Tissue Engineering

Research Interests: Heart, lung, and perfusion preservation, magnetic resonance spectroscopy

Matthias Peltz, M.D.
Satwick Rajaram, Ph.D.

Assistant Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Spatial organization of tumors by combining machine identified phenotypes and existing pathology scoring within the framework established by cancer biology

Satwick Rajaram, Ph.D.
Kimberly Reynolds, Ph.D.

Assistant Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Role of cycloxygenase-2 in radiation and chemo-resistance, role of small molecule inhibitors as radio-sensitizers

Kimberly Reynolds, Ph.D.
Debabrata Saha, Ph.D.

Associate Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Role of cycloxygenase-2 in radiation and chemo-resistance, role of small molecule inhibitors as radio-sensitizers

Debabrata Saha, Ph.D.
Dean Sherry, Ph.D.

Professor

Training Tracks: Molecular and Translational Nanomedicine; Biomedical and Molecular Imaging

Research Interests: Responsive MRI contrast agents, targeted MR and PET agents, carbon-13 tracers of metabolism, high-field magnetic resonance spectroscopy in vivo

Dean Sherry, Ph.D.
Daniel Siegwart, Ph.D.

Associate Professor

Research Interests: Polymer and materials chemistry, drug and gene delivery, RNAi, biomedical imaging, detection and treatment of cancer

Daniel Siegwart, Ph.D.
Baran Sumer, M.D.

Professor

Training Track: Molecular and Translational Nanomedicine

Research Interests: Clinical application of nanoprobes with unique nanoscale behavior

Baran Sumer, M.D.
Xiankai Sun, Ph.D.

Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Development of PET, SPECT, and MRI imaging probes to assess biological abnormalities and evaluation of disease treatment

Xiankai Sun, Ph.D.
Animesh (Aashoo) Tandon, M.D.

Assistant Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Congenital heart disease, cardiac MRI, cardiac imaging, wearable devices, predictive analytics

Animesh (Aashoo) Tandon, M.D.
Erdal Toprak, Ph.D.

Assistant Professor

Research Interests: Antibiotic resistance and sensitivity; single molecule biophysics; synthetic biology

Erdal Toprak, Ph.D.
Elena Vinogradov, Ph.D.

Associate Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Endogenous and exogenous MRI contrast agents and mechanisms in vivo, CEST and PARACEST imaging, hyperpolarization

Elena Vinogradov, Ph.D.
Jing Wang, Ph.D.

Associate Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Immunogenomics, Tumor genomics, Bioinformatics, Biostatistics, and Machine learning

Jing Wang, Ph.D
Ken Kang-Hsin Wang, Ph.D.

Associate Professor

Training Track: Biomedical and Molecular Imaging, Medical Physics

Research Interests: Biomedical optics, In Vivo cell tracking, Optical tomography-guided radiation therapy and Ultra-high dose rate irradiation

Ken Wang, Ph.D.
Tao Wang, Ph.D.

Assistant Professor

Training Track: Medical Physics

Research Interests: Bioinformatics, Biostatistics, Machine learning, Immunogenomics, and Tumor genomics

Jing Wang, Ph.D
Guanghua Xiao, Ph.D.

Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: My methodology research is focused on model development for high-dimensional data such as gene expression, epigenomics, copy number variation, proteomics, genome-wide RNAi functional screening data and brain image data.

Guanghua Xiao, Ph.D.
Yang Xie, Ph.D.

Professor

Research Interests: Biostatistics, bioinformatics, statistical genomics, clinical trial design, and biomarker studies

Yang Xie, Ph.D.
Chao Xing, Ph.D.

Associate Professor

Research Interests: Statistical genetics, genetic epidemiology, bioinformatics, gene mapping for complex traits

Chao Xing, Ph.D.
Yonghao Yu, Ph.D.

Associate Professor

Training Track: Molecular and Translational Nanomedicine

Research Interests: Mass spectrometry, post-translational modifications, quantitative proteomics, signal transduction/cancer biology and metabolism

Yonghao Yu, Ph.D.
Vlad Zaha, M.D., Ph.D.

Assistant Professor

Training Track: Biomedical and Molecular Imaging

Research Interests: Detect early changes in the mitochondrial metabolism, in situ, as a marker for asymptomatic, subclinical, doxorubicin induced cardiotoxicity
Vlad Zaha, M.D., Ph.D
Xiaowei Zhan, Ph.D.

Assistant Professor

Training Track: Medical Physics

Research Interests: Radiation therapy treatment planning, optimization techniques and algorithms, artificial intelligence technology development and applications
Xiaowei Zhan, Ph.D.
You Zhang, Ph.D.

Assistant Professor

Research Interests: 3D/4D CT/CBCT reconstruction and analysis, 4D MRI reconstruction, artificial intelligence and automation in radiation therapy, biomechanical modeling and finite element analysis, deformable registration and its application in image-guided radiation therapy, radiotherapy dose calculation and plan optimization

You Zhang, Ph.D.
Jian Zhou, Ph.D.

Assistant Professor

Research Interests: Computational Biology; Systems biology and functional Genomics; Machine learning and statistics for biomedical science; Genomic sequence-based regulation

Jian Zhou, Ph.D.

Associate Faculty

These faculty members do not accept graduate students. They participate in teaching, co-mentoring, exam and dissertation committees, and all other program activities.

Thomas Banks, Ph.D.

Assistant Professor

Research Interests: Applying new technologies to improve clinical operations, and working in partnership with physicians to develop novel techniques.

Thomas Banks, Ph.D.
Dominika Borek, Ph.D.

Associate Professor

Research Interests: Eukaryotic chromatin organization, mutational rates and spectra, biological signals and noise

Dominika Borek, Ph.D.
Jeffrey Cadeddu, M.D.

Professor

Research Interests: Urology; laparoscopy, telesurgical mentoring

Jeffrey Cadeddu, M.D.
Elizabeth Davenport, Ph.D.

Assistant Professor

Research Interests: Sub concussive head impact exposure in contact sports, traumatic brain injury, magnetoencephalography

Elizabeth Davenport, Ph.D.
Yasin Dhaher, Ph.D.

Professor

Research Interests: Understand the basic biomechanical and neurophysiological properties of the lower limb after neurological lesions. Explore the neuro-mechanical underpinnings of lower limb impairments after stroke, with the goal of informing future clinical interventions

Yasin Dhaher, Ph.D.
Robert Eberhart, Ph.D.

Professor Emeritus

Research Interests: Biomaterials; circulatory assist devices

Robert Eberhart, Ph.D.
Andrew Godley, Ph.D.

Associate Professor

Research Interests:

Andrew Godley
Junyu Guo, Ph.D.

Assistant Professor

Research Interests: Deep learning application in magnetic resonance imaging, dynamic contrast-enhanced magnetic resonance imaging (DCE- MRI)

Junyu Guo, Ph.D.
Sandra Hayden, M.A.

Assistant Professor

Research Interests: Quality assurance and student learning in Virtual vs clinical environment. Isocenter localization correlation between Radiation Therapist and Masters education program radiation therapy students. A comparison and agreement study.

Sandra Hayden, M.A
Brian Hrycushko, Ph.D.

Associate Professor

Research Interests: Tissue-Response modeling in radiation therapy

Brian Hrycushko, Ph.D.
Mustafa Husain, M.D.

Professor

Research Interests: General psychiatry, aging and geriatric issues, new applications of lead placement in ECT and novel treatments of major depressive disorder including magnetic seizure therapy, transcranial magnetic stimulation, deep brain stimulation, and vagus nerve stimulation

Mustafa Husain, M.D.
Michael Jessen, M.D.

Professor

Research Interests: Circulatory assist devices, cardiac metabolism

Michael Jessen, M.D.
Wen Jiang, M.D., Ph.D.

Assistant Professor

Research Interests: Real-time imaging of hematopoietic stem cells and their niches using two-photon intravital microscopy

Wen Jiang, M.D., Ph.D.
Romaine Johnson, M.D.

Associate Professor

Research Interests: Tissue engineering and regenerative medicine, biomaterials, biomechanics, pediatric airway disorders

Romaine Johnson, M.D.
Jayanthi Lea, M.D.

Professor

Research Interests: Cervical cancer, developmental therapeutics, ovarian cancer, early detection of ovarian cancer

Jayanthi Lea, M.D.
Matthew Lewis, Ph.D.

Assistant Professor

Research Interests: Molecular-imaging instrumentation, linear and nonlinear diffraction tomography, tensor tomography, applied inverse problems

Matthew Lewis, Ph.D.
Wen-Hong Li, Ph.D.

Associate Professor

Research Interests: Engineering probes and assays for monitoring islet beta-cell mass or function in vivo; physiological regulation of hormone secretion in pancreatic islets; functional analysis of microRNA

Wen-Hong Li, Ph.D.
Li Liu, Ph.D.

Assistant Professor

Research Interests: Development of reporter genes and evaluation of different gene reporters

Li Liu, Ph.D.
Robert Mattrey, M.D.

Professor

Research Interests: Novel molecular-based contrast agents, with emphasis on ultrasound solutions, which can be used to detect and/or treat cancer, including image guided tumor ablation, ultrasound directed drug or gene delivery, or cell-based therapy

Robert Mattrey, M.D.
Roderick McColl, Ph.D.

Professor

Research Interests: fMRI; DICOMs

Roderick McColl, Ph.D.
Paul Medin, Ph.D.

Professor

Research Interests: Tissue-response modeling in radiation therapy; stereotactic radiation therapy

Paul Medin, Ph.D.
Jimin Ren, Ph.D.

Associate Professor

Research Interests: In vivo MRS for studies of energy and phospholipids metabolism in brain and skeletal muscle

Jimin Ren, Ph.D.
Scott Smith, Ph.D.

Professor

Research Interests: Neural cardiovascular control during exercise; reflex dysfunction in heart failure; reflex dysfunction in hypertension

Scott Smith, Ph.D.
Todd Soesbe, Ph.D.

Assistant Professor

Research Interests: Clinical applications of new spectral CT technologies

Todd Soesbe, Ph.D.
Durga Udayakumar, Ph.D.

Assistant Professor

Research Interests: Radiogenomics with a special focus on identifying imaging measures extracted from quantitative MRI parameters as a noninvasive tool to better predict biological characteristics in clear cell renal cell carcinoma.

Durga Udayakumar, Ph.D.
Tre Welch, Ph.D.

Assistant Professor

Research Interests: Biomaterial grafts, coatings and scaffolds; finite element analysis; polymer synthesis; bioresorbable polymer characterization

Tre Welch, Ph.D.
Yulong Yan, Ph.D.

Associate Professor

Research Interests: High-performance computing; infrastructure for radiation therapy; radiobiological effects

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Ming Yang, M.D.

Assistant Professor

Research Interests: Adrenal disorders,r elationship between obesity and metabolic health and hyposialylation of IgG in adolescent patients

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Metin Yavuz, D.Eng.

Associate Professor

Research Interests: Diabetic foot ulcers, pressure ulcers, wound healing, medical device design, biomechanics

Metin Yavuz, D.Eng.
Takeshi Yokoo, M.D., Ph.D.

Associate Professor

Research Interests: Applied mathematics and MRI methods for translational research in liver imaging with special focus on evaluation of nonalcoholic fatty liver disease (NAFLD)

Takeshi Yokoo, M.D., Ph.D.