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Structural Biology

Protein structure determination using cryo-EM and X-ray crystallography

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Patched-1

Structures of Ptch1 monomer and in complex with Sonic Hedgehog

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TRPML1

Structure of human TRPML1 by cryo-EM

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NPC1

Structure of human Neiman-Pick C1 protein

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Xiaochun Li Lab

Biochemistry and Structural Biology