Induced Pluripotent Stem Cell Model

Our recently published model, taking ulcerative colitis fibroblast and turning them into induced pluripotent stem cells (iPSCS) and after differentation deriving induce human UC-derived organic model.


Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity

Our latest nature paper, discussing our newest model to study ulcerative colitis pathogenesis.


Metastatic Colorectal Cancer Model

Research is currently ongoing to develop a technically feasible model for human metastasis.


Cytokine Expression in Cancer and Colitic-associated Fibroblasts 

To better understand the microenvironment of colitis and cancer-associated fibroblasts we are investigating how the modulation of CXCL8 affects the pathogenesis of Colitis-associated cancer.


Currently, there are no curative, CAC-preventing, or CAC-reversing options for UC patients, as the pathogenesis remains unclear. Due to this , our long-term goal is to understand the pathogenesis of UC and CAC.

Post-Doc Opportunity Available

Position to study and assess the microenvironment, associated with colorectal cancer development and metastasis. 

Individuals should send a CV, statement of interests, & 3 references to Dr. Huang.


Dr. Emina Huang

Executive Vice Chair of Research

Professor, Colon & Rectal Surgery



Simmons Biomedical Research Building

NB5.226, UT Southwestern Medical Center

5323 Harry Hines Blvd.

Dallas, TX 75390-9169