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The Harold C. Simmons Comprehensive Cancer Center is a “matrix” cancer center, which fosters routine interaction across scientific disciplines. This ensures research discoveries are broadly leveraged to promote new progress in the fight against cancer.

These transdisciplinary interactions, along with overall depth and breadth of research, are key attributes underlying Simmons’ designation by the National Cancer Institute as one of a select group of “Comprehensive” U.S. cancer centers.

Simmons benefits from a broad base of institutional, philanthropic, community, and governmental support. Since 2010, the Cancer Prevention and Research Institute of Texas has fueled vigorous scientific efforts against cancer across the state. To date, funding from the institute to support UT Southwestern cancer research and prevention initiatives has surpassed $315 million.

Research Programs


Specialized Programs of Research Excellence (SPOREs)


Simmons Cancer Center is home to two SPOREs, prestigious programs that are funded by the National Cancer Institute to promote collaborative, interdisciplinary translational research focused on specific organ sites or groups of related cancers:


Members of the Simmons Comprehensive Cancer Center wearing blue or gray shirts wave while standing in a field

Simmons has 290 members. Members include one Nobel Laureate, 14 members of the National Academy of Sciences, five members of the National Academy of Medicine (formerly the Institute of Medicine), and 14 Howard Hughes Medical Institute investigators.

View Cancer Center Members