Research at the Harold C. Simmons Comprehensive Cancer Center is organized into five Research Programs that are supported by a Cancer Center Support Grant from the National Cancer Institute.
These complementary research programs work together to deliver Simmons Cancer Center's mission to ease the burden of cancer through ground-breaking discovery, transdisciplinary research, impactful community engagement, education, and exceptional patient care.
Promotes research to increase understanding of molecular mechanisms altered in tumor cells and their microenvironment that support cancer initiation and metastatic progression.
Focuses on the discovery of drug-like chemicals that affect biological processes causal to the development and progression of cancer.
Brings together investigators in developmental and cancer stem cell biology to discover how aberrant developmental processes contribute to initiation and progression of cancer.
Promotes, develops, and exploits mechanism-based research for improved therapy of human cancer, and serves as the main hub for therapeutic clinical trials.
Focuses on cross-cutting themes of cancer health disparities and health services research in the catchment’s safety-net systems, recognizing Dallas’s great socioeconomic and ethnic diversity.