High-Throughput Screening (HTS)
Enabling researchers to conduct carefully planned,
drug discovery research that would otherwise be prohibitively expensive for single laboratories.
UT Southwestern Medical Center's High-Throughput Screening (HTS) Core Facility allows Principal Investigators in the University and the Harold C. Simmons Comprehensive Cancer Center to use the techniques of high-throughput screening of compounds or genomic siRNA libraries. The compounds identified in such experiments can be used as research tools to understand the complex molecular relationships that cause or prevent disease (e.g. cancer, neurodegeneration, metabolic diseases, parasitic infections, etc.) as well as possible candidates for eventual drug development. The proteins associated with genes identified in high throughput functional genomics experiments may become eventual targets for compound screens, leading to novel therapeutics.