BioScan NanoSPECT/CT Plus

BioScan NanoSPECT
BioScan NanoSPECT

Single-photon emission computed tomography (SPECT) is a nuclear medicine tomographic imaging technique using gamma rays. Although similar to conventional nuclear medicine planar imaging using a gamma camera, it provides true 3D information.

Unlike Positron Emission Tomography (PET), which relies on 511 KeV coincidences resulting from positron and electron annihilations, SPECT detects a wide range of gamma rays from 10 KeV to 300 KeV or broader as necessary. Simply put, it provides a “spectrumlike” readout that enables in vivo imaging of multiple biological events or different components of a single injection.

The Small Animal Imaging core facility is equipped with a BioScan NanoSPECT/CT Plus, a dual modality system for imaging mice, rats, and small rabbits. The system is capable of imaging a range of isotopes from the low energy of 125I to 111In, alone or in dual isotope acquisition mode. It is capable of high sensitivity submillimeter imaging, dynamic SPECT, and gated cardiac SPECT imaging.

An optional integrated animal handling system provides a pathogen-free imaging environment.

Resolution Sub-mm (>0.4 mm); uniform in small volumes
8X better volumetric resolution
Sensitivity Average: 0.3 to 0.4%
Axial FOV (FOV) 2.6 cm (one position) to 27cm (helical scan)
Transaxial FOV (TFOV) Up to 20 cm
Suitability Best for larger proteins, peptides, antibody fragments, hormones
Common Isotopes I-125, Ga-57, Tc-99m, I-123, Lu-177, In-11, I-131
X-ray Source Standard micro-focus
Focal Spot 5-8 µm
Maximum Resolution 39 µm
Capabilities Cardiac and Respiratory Gating

See the Image Gallery.