Summer Research Program for Students 2019
The 2019 STARS Summer Research Program for Students included 58 students from Dallas-Fort Worth and surrounding areas. This eight-week program gave students an opportunity to work side-by-side with a faculty host in a research laboratory. It consisted of activities, seminars, and an individualized research project that contributed to the advancement of science. The students were able to showcase and share these advancements during the end-of-program scientific poster session.

Jaila Acevedo
Irma Lerma Rangel Young Women's Leadership School
Mentor: Charlie Khemtong, Ph.D.
Is the Heart Ketogenic?
Irma Lerma Rangel Young Women's Leadership School
Mentor: Charlie Khemtong, Ph.D.
Is the Heart Ketogenic?

Emmanuella Alawode
South Grand Prairie High School
Mentor: Zhi-Ping Liu, Ph.D.
Development of A Novel Small Molecule Inhibitor of Jumonji C Domain-containing Histone Demethylases for Treatment of Castration-resistant Prostate Cancer
South Grand Prairie High School
Mentor: Zhi-Ping Liu, Ph.D.
Development of A Novel Small Molecule Inhibitor of Jumonji C Domain-containing Histone Demethylases for Treatment of Castration-resistant Prostate Cancer

Ariel Alexander
Harmony Science Academy Dallas
Mentor: Linda Baker, M.D.
Prune Belly Syndrome Filamin A Mutations Cause Altered Smoothelin Muscle Expression in Visceral Smooth Muscle
Harmony Science Academy Dallas
Mentor: Linda Baker, M.D.
Prune Belly Syndrome Filamin A Mutations Cause Altered Smoothelin Muscle Expression in Visceral Smooth Muscle

Yunbeen Bae
Reedy High School
Mentor: Pradeep Mammen, M.D.
Molecular Benefits of Activating Vasoactive Intestinal Peptide in Preventing DMD-Associated Cardiomyopathy
Reedy High School
Mentor: Pradeep Mammen, M.D.
Molecular Benefits of Activating Vasoactive Intestinal Peptide in Preventing DMD-Associated Cardiomyopathy

Janelle Baker
School of Science and Engineering at the Yvonne A. Ewell Townview Magnet Center
Mentors: Jerry Shay, Ph.D. and Beatriz Fontoura, Ph.D.
Compounds SW053772 and 336898 as Inhibitors of Liver Cancer Cell Growth and Invasion
School of Science and Engineering at the Yvonne A. Ewell Townview Magnet Center
Mentors: Jerry Shay, Ph.D. and Beatriz Fontoura, Ph.D.
Compounds SW053772 and 336898 as Inhibitors of Liver Cancer Cell Growth and Invasion

Chaitanya Bashyam
Edward S. Marcus High School
Mentor: Yuh Min Chook, Ph.D.
Biochemical Studies of Kapβ2 with hnRNP A/B NLS
Edward S. Marcus High School
Mentor: Yuh Min Chook, Ph.D.
Biochemical Studies of Kapβ2 with hnRNP A/B NLS

Ermias Belay
Jesuit College Preparatory School of Dallas
Mentor: Dayoung Oh, Ph.D.
Determining the Gene Expression of GPR84 in C2C12 Muscle Cells During Differentiation
Jesuit College Preparatory School of Dallas
Mentor: Dayoung Oh, Ph.D.
Determining the Gene Expression of GPR84 in C2C12 Muscle Cells During Differentiation

Katelyn Candido
School of Science and Engineering at the Yvonne A. Ewell Townview Magnet Center
Mentor: Todd Roberts, Ph.D.
Gene Expression Patterns in Single Cells in RA, a Brain Region Associated with Song Production in Zebra Finches
School of Science and Engineering at the Yvonne A. Ewell Townview Magnet Center
Mentor: Todd Roberts, Ph.D.
Gene Expression Patterns in Single Cells in RA, a Brain Region Associated with Song Production in Zebra Finches

Emily Caplan
Greenhill School
Mentor: Steven Gray, Ph.D.
AAV Capsid Engineering for Central Nervous System Gene Therapy
Greenhill School
Mentor: Steven Gray, Ph.D.
AAV Capsid Engineering for Central Nervous System Gene Therapy

Jack Casey
Jesuit College Preparatory School
Mentor: Genevieve Konopka, Ph.D.
Cognitive Behavioral Testing of CLOCK and HuCLOCK Modified Mice
Jesuit College Preparatory School
Mentor: Genevieve Konopka, Ph.D.
Cognitive Behavioral Testing of CLOCK and HuCLOCK Modified Mice

Katherine Corey
Highland Park High School
Mentor: Vinod Mootha, M.D.
Mutant RNA and the Molecular Mechanisms for Fuchs Dystrophy
Highland Park High School
Mentor: Vinod Mootha, M.D.
Mutant RNA and the Molecular Mechanisms for Fuchs Dystrophy

Peter Dadson
School of Health Professions at the Yvonne A. Ewell Townview Magnet Center
Mentor: Madhukar Trivedi, M.D.
Associations Between Plasma FGF21 and Anhedonia
School of Health Professions at the Yvonne A. Ewell Townview Magnet Center
Mentor: Madhukar Trivedi, M.D.
Associations Between Plasma FGF21 and Anhedonia

Varsha Danda
The Hockaday School
Mentor: Kathryn O'Donnell, Ph.D.
Investigation of SET Oncoprotein Function in PCDH7-Mediated Lung Tumorigenesis
The Hockaday School
Mentor: Kathryn O'Donnell, Ph.D.
Investigation of SET Oncoprotein Function in PCDH7-Mediated Lung Tumorigenesis

Sindhuja Darisipudi
Uplift North Hills Preparatory
Mentor: Dominika Borek, Ph.D.
Purification and Structural Characterization of Standard for Cryo-EM
Uplift North Hills Preparatory
Mentor: Dominika Borek, Ph.D.
Purification and Structural Characterization of Standard for Cryo-EM

Audrey DeJong
Richardson High School
Mentor: David Mangelsdorf, Ph.D.
Pancreatic Cancer is Characterized by Loss of β-Klotho and FGF21
Richardson High School
Mentor: David Mangelsdorf, Ph.D.
Pancreatic Cancer is Characterized by Loss of β-Klotho and FGF21

Ritesh Dontula
Coppell High School
Mentor: Maria Chahrour, Ph.D.
The Effect of UBE3B Loss on Calcium Signaling Pathway
Coppell High School
Mentor: Maria Chahrour, Ph.D.
The Effect of UBE3B Loss on Calcium Signaling Pathway

Delaney Feagans
Young Women's Leadership Academy at Arnold
Mentor: Jennifer Kohler, Ph.D.
Effect of O-GlcNAc on the Activity of Transcriptional Activators
Young Women's Leadership Academy at Arnold
Mentor: Jennifer Kohler, Ph.D.
Effect of O-GlcNAc on the Activity of Transcriptional Activators

Abel Fetahi
School for the Talented and Gifted at the Yvonne A. Ewell Townview Magnet Center
Mentor: Genevieve Konopka, Ph.D.
A Weighted Gene Coexpression Network Analysis on Single Cell Transcriptomics Data
School for the Talented and Gifted at the Yvonne A. Ewell Townview Magnet Center
Mentor: Genevieve Konopka, Ph.D.
A Weighted Gene Coexpression Network Analysis on Single Cell Transcriptomics Data

Varun Gande
Greenhill School
Mentor: James Kim, M.D., Ph.D.
Loss of Hedgehog Ligand Reduces Levels of Hypoxia in Mice, Causing Reactive Oxygen Species Levels to Rise
Greenhill School
Mentor: James Kim, M.D., Ph.D.
Loss of Hedgehog Ligand Reduces Levels of Hypoxia in Mice, Causing Reactive Oxygen Species Levels to Rise

Meera Gangasani
Episcopal School Of Dallas
Mentor: John Minna, M.D.
Identification of Drugs that Generate a Synergistic Anti-cancer Effect in Combination with Cisplatin-Etoposide Treatment in SCLC Utilizing an FDA Drug Targeting CRISPR Library
Episcopal School Of Dallas
Mentor: John Minna, M.D.
Identification of Drugs that Generate a Synergistic Anti-cancer Effect in Combination with Cisplatin-Etoposide Treatment in SCLC Utilizing an FDA Drug Targeting CRISPR Library

Aileen Garcia
Emmett J. Conrad High School
Mentor: Prasanna Alluri, M.D., Ph.D.
Novel CDK4/6 Degraders in ER+ Breast Cancer
Emmett J. Conrad High School
Mentor: Prasanna Alluri, M.D., Ph.D.
Novel CDK4/6 Degraders in ER+ Breast Cancer

Jon Graswich
Byron Nelson High School
Mentor: David Corey, Ph.D.
Localization and Expression of Ago2 Related to Cellular Stress
Byron Nelson High School
Mentor: David Corey, Ph.D.
Localization and Expression of Ago2 Related to Cellular Stress

Amyia Green
Young Women's Leadership Academy
Mentor: Xiankai Sun, Ph.D.
Evaluation of L-5-[18F]-Fluorotryptophan for PET Imaging of Renal Cell Carcinomas
Young Women's Leadership Academy
Mentor: Xiankai Sun, Ph.D.
Evaluation of L-5-[18F]-Fluorotryptophan for PET Imaging of Renal Cell Carcinomas

Ryan Hammond
John Paul II High School
Mentor: Kevin Dean, Ph.D.
Visualizing Microtubules Through DNA Cloning
John Paul II High School
Mentor: Kevin Dean, Ph.D.
Visualizing Microtubules Through DNA Cloning

Megan Harvey
MacArthur High School
Mentor: Jacques Lux, Ph.D.
Development of pH-Sensitive Microbubbles for Ultrasound Cancer Detection
MacArthur High School
Mentor: Jacques Lux, Ph.D.
Development of pH-Sensitive Microbubbles for Ultrasound Cancer Detection

Hafsa Hashmi
Brighter Horizons Academy
Mentor: Zhao Wang, Ph.D.
Role of Protein Kinase RNA (PKR)-like ER Kinase (PERK) in Myocardial Ischemia-Reperfusion Injury
Brighter Horizons Academy
Mentor: Zhao Wang, Ph.D.
Role of Protein Kinase RNA (PKR)-like ER Kinase (PERK) in Myocardial Ischemia-Reperfusion Injury

Samara Huckvale
Wylie East High School
Mentor: E. Sherwood Brown, M.D., Ph.D.
The Examination of an Association Between Inflammatory Biomarker GlycA and Depression
Wylie East High School
Mentor: E. Sherwood Brown, M.D., Ph.D.
The Examination of an Association Between Inflammatory Biomarker GlycA and Depression

Haaris Jilani
Harmony Science Academy Euless
Mentor: Ping Mu, Ph.D.
Investigating Mechanisms of Antiandrogen Resistance in Prostate Cancer
Harmony Science Academy Euless
Mentor: Ping Mu, Ph.D.
Investigating Mechanisms of Antiandrogen Resistance in Prostate Cancer

Toshiki Kato
MacArthur High School
Mentor: Noelle Williams, Ph.D.
Lysosomal Sequestration of Drugs in Human Colon Cells
MacArthur High School
Mentor: Noelle Williams, Ph.D.
Lysosomal Sequestration of Drugs in Human Colon Cells

Aaron Libed
Mansfield Lake Ridge High School
Mentor: Ganesh Raj, M.D., Ph.D.
Therapeutic Combination-induced Synthetic Lethality in Lung and Pancreatic Cancers
Mansfield Lake Ridge High School
Mentor: Ganesh Raj, M.D., Ph.D.
Therapeutic Combination-induced Synthetic Lethality in Lung and Pancreatic Cancers

Katherine Long
McKinney Boyd High School
Mentor: James Brugarolas, M.D., Ph.D.
Activity of TAK-243 in BAP1-deficient and BAP1-reconstituted ccRCC Cells
McKinney Boyd High School
Mentor: James Brugarolas, M.D., Ph.D.
Activity of TAK-243 in BAP1-deficient and BAP1-reconstituted ccRCC Cells

Steven Lu
Lebanon Trail High School
Mentor: Ondine Cleaver, Ph.D.
Cyp26B1 is Required to Guide Semilunar Valve Leaflet Remodeling and Restrict Endocardial Cell Proliferation
Lebanon Trail High School
Mentor: Ondine Cleaver, Ph.D.
Cyp26B1 is Required to Guide Semilunar Valve Leaflet Remodeling and Restrict Endocardial Cell Proliferation

Priya Mandava
Allen High School
Mentor: Michael Buszczak, Ph.D.
Characterization of an Endogenous Translation Reporter Using Bimolecular Fluorescence Technique in Drosophila Melanogaster
Allen High School
Mentor: Michael Buszczak, Ph.D.
Characterization of an Endogenous Translation Reporter Using Bimolecular Fluorescence Technique in Drosophila Melanogaster

Ashwin Mathew
Hebron High School
Mentor: Wei Xu, Ph.D.
Tracing of the Rewiring of Neuronal Circuits Involved in Learning and Memory
Hebron High School
Mentor: Wei Xu, Ph.D.
Tracing of the Rewiring of Neuronal Circuits Involved in Learning and Memory

Caitlin McAlanis
North Forney High School
Mentors: Douglas Strand, Ph.D.
Comparative Cellular Anatomy of the Mouse and Human Bladder
North Forney High School
Mentors: Douglas Strand, Ph.D.
Comparative Cellular Anatomy of the Mouse and Human Bladder

Carlos Medrano
School of Science and Engineering Magnet at Yvonne A. Ewell Townview Center
Mentor: Xun Jia, Ph.D.
Deep Learning Based Automatic Organ Segmentation for Small Animals
School of Science and Engineering Magnet at Yvonne A. Ewell Townview Center
Mentor: Xun Jia, Ph.D.
Deep Learning Based Automatic Organ Segmentation for Small Animals

Amber Miranda
School for the Talented and Gifted at the Yvonne A. Ewell Townview Magnet Center
Mentor: Evan Nair-Gill, M.D., Ph.D.
Cellular Mechanisms of a Clinically Relevant Mutation in Pacs1
School for the Talented and Gifted at the Yvonne A. Ewell Townview Magnet Center
Mentor: Evan Nair-Gill, M.D., Ph.D.
Cellular Mechanisms of a Clinically Relevant Mutation in Pacs1

Riya Mohan
Grapevine Senior High School
Mentor: Ezra Burstein, M.D., Ph.D.
The Role of Endosomal Recycling in NF-kB Pathway Activation
Grapevine Senior High School
Mentor: Ezra Burstein, M.D., Ph.D.
The Role of Endosomal Recycling in NF-kB Pathway Activation

Zac Nguyen
Garland High School
Mentor: Melanie Cobb, Ph.D.
The Role of WNK1 in the Regulation of β–Catenin and Adherens Junctions
Garland High School
Mentor: Melanie Cobb, Ph.D.
The Role of WNK1 in the Regulation of β–Catenin and Adherens Junctions

William Nickols
Jesuit College Preparatory School of Dallas
Mentor: Yunsun Nam, Ph.D.
DEAD-box Helicase Binding aAfinity to G-quadruplexes
Jesuit College Preparatory School of Dallas
Mentor: Yunsun Nam, Ph.D.
DEAD-box Helicase Binding aAfinity to G-quadruplexes

Jennifer Okolo
Wylie High School
Mentor: Kevin Williams, Ph.D.
Treatment of Obesity with Celastrol Requires eif2α in POMC Neurons
Wylie High School
Mentor: Kevin Williams, Ph.D.
Treatment of Obesity with Celastrol Requires eif2α in POMC Neurons

Daniella Padron-Castillo
Duncanville High School
Mentor: Asaithamby Aroumougame, Ph.D.
Expression of TRF2-DN Induces Cancer in Human Cells
Duncanville High School
Mentor: Asaithamby Aroumougame, Ph.D.
Expression of TRF2-DN Induces Cancer in Human Cells

Nathan Paul
Cistercian Preparatory School
Mentor: Joel Goodman, Ph.D.
The “Linker” Region of Seipin Is Important for Lipid Droplet Morphology
Cistercian Preparatory School
Mentor: Joel Goodman, Ph.D.
The “Linker” Region of Seipin Is Important for Lipid Droplet Morphology

Nidhi Pawate
Allen High School
Mentor: Ivan D’Orso, Ph.D.
Characterizing the Histone 4 Binding Activity of Master Transcriptional Regulator KAP1
Allen High School
Mentor: Ivan D’Orso, Ph.D.
Characterizing the Histone 4 Binding Activity of Master Transcriptional Regulator KAP1

Sameen Rahman
Uplift North Hills Preparatory
Mentor: Srinivas Malladi, Ph.D.
Metabolic Reprogramming Drives Metastatic Breakout in Breast Cancer
Uplift North Hills Preparatory
Mentor: Srinivas Malladi, Ph.D.
Metabolic Reprogramming Drives Metastatic Breakout in Breast Cancer

Matthew Raroque
St. Mark's School of Texas
Mentor: Steven Vernino, M.D., Ph.D.
Antibodies against Muscarinic Acetylcholine Receptors in POTS
St. Mark's School of Texas
Mentor: Steven Vernino, M.D., Ph.D.
Antibodies against Muscarinic Acetylcholine Receptors in POTS

Rebekah Rohrs
Nimitz High School
Mentor: Carol S. North, M.D.
Filicide and Postpartum Psychosis: A Review
Nimitz High School
Mentor: Carol S. North, M.D.
Filicide and Postpartum Psychosis: A Review

Isabel Schaffer
The Hockaday School
Mentors: Michael Brown, M.D. and Joseph Goldstein, M.D.
Mechanistic Studies of Triazole Binding to Niemann-Pick C1 Protein
The Hockaday School
Mentors: Michael Brown, M.D. and Joseph Goldstein, M.D.
Mechanistic Studies of Triazole Binding to Niemann-Pick C1 Protein

Armaan Sood
Imagine International Academy of North Texas
Mentor: Elizabeth Maher, M.D., Ph.D.
Glioblastoma Nuclei Undergo Marked Deformation and Reduction in Size when Migrating through Confined Spaces
Imagine International Academy of North Texas
Mentor: Elizabeth Maher, M.D., Ph.D.
Glioblastoma Nuclei Undergo Marked Deformation and Reduction in Size when Migrating through Confined Spaces

Shanivi Srikonda
Irving High School
Mentor: Lee Kraus, Ph.D.
Role of Poly(ADP-Ribose) Polymerase 1 in Trophoblast Differentiation
Irving High School
Mentor: Lee Kraus, Ph.D.
Role of Poly(ADP-Ribose) Polymerase 1 in Trophoblast Differentiation

Khyathi Thallapureddy
Texas Academy of Mathematics and Science
Mentor: Chen Liu, Ph.D.
Human Genetic Variant OtpQ153R Causes Excessive Weight Gain and Glucose Intolerance in Mice
Texas Academy of Mathematics and Science
Mentor: Chen Liu, Ph.D.
Human Genetic Variant OtpQ153R Causes Excessive Weight Gain and Glucose Intolerance in Mice

Jordan Thompson
Greenhill School
Mentor: John Hulleman, Ph.D.
The Development of New Tools to Control the Unfolded Protein Response
Greenhill School
Mentor: John Hulleman, Ph.D.
The Development of New Tools to Control the Unfolded Protein Response

Risha Dianne Valera
Plano West High School
Mentor: Helmut Kramer, Ph.D.
Characterizing phosphatase CG6036 in the Dephosphorylation of Drosophila Melanogaster Acinus
Plano West High School
Mentor: Helmut Kramer, Ph.D.
Characterizing phosphatase CG6036 in the Dephosphorylation of Drosophila Melanogaster Acinus

Daniela Vallejo
The Hockaday School
Mentor: Kim Orth, Ph.D.
Characterizing Putative Virulence Factor VPA1328 in Vibrio Parahaemolyticus
The Hockaday School
Mentor: Kim Orth, Ph.D.
Characterizing Putative Virulence Factor VPA1328 in Vibrio Parahaemolyticus

Sarah Visokay
Ursuline Academy of Dallas
Mentor: John Abrams, Ph.D.
Genetic Analysis of Remodeling Substrates Targeted by the Apoptosome
Ursuline Academy of Dallas
Mentor: John Abrams, Ph.D.
Genetic Analysis of Remodeling Substrates Targeted by the Apoptosome

Michelle Wu
Carroll Senior High School
Mentor: Shaheen Khan, Ph.D.
Understanding the Development of Autoimmune Events in Patients Receiving Immune Checkpoint Inhibitor Therapy
Carroll Senior High School
Mentor: Shaheen Khan, Ph.D.
Understanding the Development of Autoimmune Events in Patients Receiving Immune Checkpoint Inhibitor Therapy

Nathan Wulfekammer
Plano Senior High School
Mentor: Mark Henkemeyer, Ph.D.
Impact of EphrinB Reverse Signaling on Interneuron Population and Distribution
Plano Senior High School
Mentor: Mark Henkemeyer, Ph.D.
Impact of EphrinB Reverse Signaling on Interneuron Population and Distribution

Layla Zonouzy
McKinney North High School
Mentor: Jim Collins, Ph.D.
Functional Heterogeneity in Schistosome Tegument Progenitors: A “Skin” Teresting Study of Progenitor Specification
McKinney North High School
Mentor: Jim Collins, Ph.D.
Functional Heterogeneity in Schistosome Tegument Progenitors: A “Skin” Teresting Study of Progenitor Specification