Molecular and Genetic Diagnostics

The transfer of molecular biology technology from basic research provides the pathologist with a host of new tools to aid in the diagnosis of disease. The Laboratory for Molecular Diagnostics is a state-of-the-art laboratory capable of utilizing cutting-edge molecular techniques to help answer difficult diagnostic problems.
Quality is assured throughout the testing process beginning with robust assay design and technical and clinical validation. CAP and commercial proficiency testing and sample exchange provide assurance of assay integrity. The academic setting provides further enhancement of the assays’ clinical utility as researched by pathology residents and molecular pathology fellows participating in clinical investigations.
Every sample is analyzed by dedicated technologists who are experts in the performance of molecular techniques. Assays for hematologic, infectious, and inherited disorders are performed. The assay formats include Sanger and next generation DNA sequencing, real-time quantitative PCR, Sequenom mass spec, and fragment analysis.
Faculty

Prasad Koduru, Ph.D.
- Professor
- Medical Director of Genetics Diagnostics Laboratories
- Fellowship Director of Clinical Cytogenetics
- UTSW – BioCenter
- Prasad.Koduru@UTSouthwestern.edu

Jeffrey Gagan, M.D.,Ph.D.
- Assistant Professor
- Medical Director Next Generation Sequencing
- UTSW – BioCenter
- Jeffrey.Gagan@UTSouthwestern.edu
- Publications

James S. Malter, M.D.
- Professor and Chair of Pathology
- UTSW – North Campus
- James.Malter@UTSouthwestern.edu
- Malter Lab
- Publications

Dwight Oliver, M.D.
- Professor
- Director of Molecular Diagnostics laboratory
- Fellowship Director of Molecular Genetics
- UTSW – BioCenter
- Dwight.Oliver@UTSouthwestern.edu

Jason Park, M.D., Ph.D.
- Professor
- Clinical Director of Advanced Diagnostics
- Children’s Health℠
- JASON.PARK@childrens.com
Jeffrey SoRelle, M.D.
- Assistant Professor
- UTSW – BioCenter
- Jeffrey.SoRelle@UTSouthwestern.edu

Ward Wakeland, Ph.D.
- Professor
- UTSW – BioCenter
- Edward.Wakeland@UTSouthwestern.edu

Kathleen Wilson, M.D.
- Professor
- UTSW – BioCenter
- Kathleen.Wilson@UTSouthwestern.edu

Dr. Jing Xu, M.D., Ph.D.
- Assistant Instructor
- UTSW-Biocenter
- Jing.Xu@UTSouthwestern.edu