Molecular and Translational Nanomedicine

The Molecular and Translational Nanomedicine (MTN) track is designed for students who are interested in molecular design of nanomedicine platforms to help translate basic biological science to clinical medicine.

Faculty members in the MTN track are from a diverse scientific, engineering, and clinical background to offer a highly interdisciplinary training environment. Molecular design and nano engineering are closely integrated with pathophysiology and biology rationales to establish emerging precision paradigms for disease diagnosis and therapy.

MTN is ideally suited for students with strong engineering, physical science, or biology background and a keen desire to cross the boundaries between traditional scientific disciplines.

Research Topics

Selected research topics include:

  • Nano delineation of tumor boundaries for image-guided cancer surgery
  • Minimalist nanovaccine for immunotherapy
  • Theranostic nanomedicine integrating imaging and therapeutic delivery targeting diabetes or cancer
  • Cancer-targeted siRNA/miRNA delivery and therapy

Track Co-Directors

Jinming Gao, Ph.D.
Jinming Gao, Ph.D.

Professor

Research Interests: Precision cancer nanomedicine, nano-immune-engineering, nanovaccine, theranostic nanomedicine for tumor-targeted immunotherapy

Baran Sumer, M.D.
Baran Sumer, M.D.

Professor

Research Interests: Clinical application of nanoprobes with unique nanoscale behavior

Faculty

Ian Corbin, Ph.D.

Associate Professor

Research Interests: Molecular imaging techniques and nanomedicine-technology development to better understand and characterize liver disease

Yang-Xin Fu, M.D., Ph.D..

Professor

Training Track: Molecular and Translational Nanomedicine

Research Interests: Cancer microenvironment, tumor targeted immunotherapy, antibody engineering, anti-cancer treatment-induced immune responses

Yang-Xin Fu, M.D., Ph.D.
Caroline de Gracia Lux, Ph.D.

Assistant Professor

Training Track: Molecular and Translational Nanomedicine

Research Interests: Ultrasound contrast agent, perfluorocarbon emulsions, development of new ultrasound-based strategies for early detection and treatment of diseases

Caroline de Gracia Lux, Ph.D.
Jacques Lux, Ph.D.

Assistant Professor

Research Interests: Bioresponsive nanomaterials for in vivo detection and therapy; targeted and activatable ultrasound agents for the detection of inflammation and cancer; ultrasound-based gene delivery platforms

Jacques Lux, Ph.D.
Ralph P. Mason, Ph.D., C.Sci., C.Chem.

Professor

Research Interests: Tumor pathophysiology, development of novel therapeutics and prognostic imaging biomarkers based on MRI, optical and photoacoustic imaging.

Ralph Mason, Ph.D.
Dean Sherry, Ph.D.

Professor

Research Interests: Responsive MRI contrast agents, targeted MR and PET agents, carbon-13 tracers of metabolism, high-field magnetic resonance spectroscopy in vivo

Dean Sherry, Ph.D.
Daniel Siegwart, Ph.D.

Associate Professor

Research Interests: Polymer and materials chemistry, drug and gene delivery, RNAi, biomedical imaging, detection and treatment of cancer

Daniel Siegwart, Ph.D.
Xiankai Sun, Ph.D.

Professor

Research Interests: Development of PET, SPECT, and MRI imaging probes to assess biological abnormalities and evaluation of disease treatment

Xiankai Sun, Ph.D.
Yonghao Yu, Ph.D.

Associate Professor

Training Track: Molecular and Translational Nanomedicine

Research Interests: Mass spectrometry, post-translational modifications, quantitative proteomics, signal transduction/cancer biology and metabolism

Yonghao Yu, Ph.D.
 

Associate Members

These faculty members do not accept graduate students. They participate in teaching, co-mentoring, exam and dissertation committees, and all other program activities.

Jeffrey Cadeddu, M.D.

Professor

Research Interests: Urology; laparoscopy, telesurgical mentoring

Jeffrey Cadeddu, M.D.
Zoltan Kovacs, Ph.D.

Assistant Professor

Research Interests: Molecular and functional imaging, rational design of bifunctional ligands, targeted MRI contrast agents and radiopharmaceuticals

Zoltan Kovacs, Ph.D.
Jayanthi Lea, M.D.

Professor

Research Interests: Cervical cancer, developmental therapeutics, ovarian cancer, early detection of ovarian cancer

Jayanthi Lea, M.D.