News
Ovarian cancer cells use stress hormone signaling to shut down immune system
When activated in ovarian cancer cells, the receptor for the body’s primary stress hormone alters the tumor environment in ways that blunt immune response, according to new research led by UT Southwestern Medical Center.
Human cells can exchange genomic DNA that alters cell behavior
Scientists at Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered that large pieces of DNA can transfer directly between human cells, and the DNA can persist and change how the recipient cell functions.
Protein coordinates responses to environmental stress
UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes – an ability known as phenotypic plasticity.
UTSW molecular biologist Benjamin Sabari, Ph.D., to receive Pershing Square Sohn Cancer Prize
Benjamin Sabari, Ph.D., Assistant Professor in the Cecil H. and Ida Green Center for Reproductive Biology Sciences and of Molecular Biology at UT Southwestern Medical Center, has been selected for a 2026 Pershing Square Sohn Cancer Prize.
Study links cancer metabolism to DNA replication errors
Loss of an enzyme necessary for a process called lipoylation disrupts the way cancer cells copy their DNA, increasing their vulnerability to a class of anticancer drugs known as PARP inhibitors, a study led by UT Southwestern Medical Center researchers shows.