News
UTSW researchers identify new immunotherapy target
Researchers at UT Southwestern Medical Center have discovered how a hormone interacts with a receptor on the surface of immune cells to shield cancer cells from the body’s natural defenses. The findings, published in Nature Immunology, could lead to new immunotherapy approaches for treating cancer as well as potential treatments for inflammatory disorders and neurologic diseases.
UTSW Research: Anaphylaxis hospital stays, LDL-lowering drug, and more
A team of researchers including UT Southwestern Medical Center Pediatrics faculty members Jo-Ann Nesiama, M.D., Professor, and Geetanjali Srivastava, M.D., M.P.H., Associate Professor, collected data on 5,641 ED visits for pediatric anaphylaxis between 2016 and 2019 from 30 hospitals in the U.S. and one in Canada.
UTSW Research: Treating shoulder pain, aortic valve procedures, and more
Millions of Americans have chronic shoulder pain, which can have a significant impact on quality of life. Although some get relief from medications, physical therapy, or joint injections, those with persistent pain often pursue more aggressive treatments such as surgeries and permanent neurostimulator implants.
Heat-related illnesses among children on the rise
Higher summer temperatures are resulting in more children seeking emergency care for heat-related illnesses, with nearly 1 in 5 needing hospitalization, according to new research from UT Southwestern Medical Center published in Academic Pediatrics.
Gene editing treats smooth muscle disease in preclinical model
Using gene editing in a preclinical model, researchers at UT Southwestern Medical Center blocked the symptoms of a rare smooth muscle disease before they developed. Their findings, published in Circulation, could eventually lead to gene therapies for this and other genetic diseases affecting smooth muscle cells.
Children’s Research Institute scientists uncover unique pathway tumors use to acquire antioxidant lipids
Scientists have discovered tumors can tap a nontraditional pathway to acquire lipoproteins – molecules that transport fat in blood – which enriches cancer cells with an antioxidant shield to survive stress, according to new research from Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Nature.
Study reveals disparities in mental health care for Texas youth
Young patients from lower-income households in Texas may not be getting the most effective treatment for severe depression and suicidal thoughts, based on findings from researchers at UT Southwestern Medical Center.
Common analgesic gas aids in opening of blood-brain barrier
Nitrous oxide, a commonly used analgesic gas, improved temporary opening of the blood-brain barrier (BBB) and gene therapy delivery in mouse models using focused ultrasound (FUS), UT Southwestern Medical Center researchers report in a new study.
Protein linked to immunotherapy resistance in kidney cancer
A protein identified by researchers at UT Southwestern Medical Center may drive resistance to immune checkpoint inhibitors, a widely used form of immunotherapy to treat cancer.
UT Southwestern and Children’s Health receive record-setting gift from Moody Foundation
UT Southwestern Medical Center and Children’s Health℠ today announced a historic nine-figure grant from the Moody Foundation to support the new $5 billion pediatric campus in Dallas, which broke ground in October 2024. The new hospital will help meet the increasing demand for pediatric health care, research and training. The Moody Foundation’s transformational grant is the largest gift to date for this landmark project.