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How to boost enrollment of Black, Hispanic patients in pediatric clinical trials

 

While Black and Hispanic families are enthusiastic about research participation, other provider and systems-focused factors may influence their involvement in pediatric oncology clinical trials, a new UT Southwestern Medical Center-led study has found.

Autoantibodies could play key role in cancer progression and prevention

 

Scientists have long sought to understand why some people with no known risk factors develop cancer while others with significant risk never do.

GLP-1 use rising rapidly among U.S. adolescents, young adults

 

Adolescents and young adults in the U.S. are increasingly using popular GLP-1 weight-loss drugs alone or in conjunction with metabolic and bariatric surgery (MBS) to manage obesity.

New biosensor tracks down missing metabolite from childhood brain disorder

 

Scientists at Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered why babies born with a rare inborn error of metabolism, called GPT2 deficiency, suffer from severe neurological impairment, according to research published in Science.

Metabolites produced by gut bacteria may protect against fungal infection

 

A metabolic byproduct formed when gut bacteria break down dietary fiber appears to protect against dangerous fungal infections common in immunocompromised patients, a study led by UT Southwestern Medical Center researchers shows.

Gut bacteria boost immune system, help send vitamin A to T cells

 

Scientists at UT Southwestern Medical Center have discovered that gut bacteria help regulate the development of the body’s immune system by directing the movement of vitamin A through a previously unrecognized cellular network.

Exertion tests offer insight into recovery from youth concussions

 

Clinical exams that incorporate gait analysis after physical exertion may provide insight into how youths are recovering after concussions to help determine whether they are ready to return to sports, UT Southwestern Medical Center and Scottish Rite for Children (SRC) physicians found.

Steep drop in metabolic coenzyme could trigger preterm labor

 

Declining placental concentrations of a molecule that plays a key role in metabolism appear to trigger the end of pregnancy and hasten labor and delivery, suggests a study co-led by researchers at UT Southwestern Medical Center.

UTSW Research: T cells, lung health, cash support for heart patients

 

Researchers at UT Southwestern Medical Center have developed a computational method that reveals how immune cells navigate the complex environment inside tumors, offering insights that could inform future cancer therapies.

Human cells can exchange genomic DNA that alters cell behavior

 

Scientists at Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered that large pieces of DNA can transfer directly between human cells, and the DNA can persist and change how the recipient cell functions.