News
Immune protein STING key for repairing, generating lysosomes
– The STING protein, known for helping cells fight viral infections by generating inflammation, also appears to function as a quality control sensor for organelles that serve as cellular waste disposal systems, UT Southwestern Medical Center researchers found. Their study, published in Molecular Cell, helps explain critical features of diseases called lysosomal storage disorders and could eventually lead to new treatments for these and other neurodegenerative diseases.
Grant worth up to $5 million aids research for cerebellar disorders
A multidisciplinary team of UT Southwestern Medical Center specialists, led by Nader Pouratian, M.D., Ph.D., and Peter Tsai, M.D., Ph.D., has received a grant worth up to $5 million from the Raynor Cerebellum Project to develop neuromodulation therapies for patients with cerebellar disorders of the brain.
UT Southwestern Q&A: What you need to know about the measles
The outbreak of measles that started in West Texas in January and spread to other regions and states has focused renewed attention on a childhood disease that had been eliminated in the United States in recent decades.
The perfect match: UTSW students open envelopes to residency futures
Members of UT Southwestern Medical School’s Class of 2025 gathered with anticipation inside the Bryan Williams, M.D., Student Center gymnasium Friday morning to learn where they will begin the next phase of their training as residents.
Protein plays dual role in causing, preventing sepsis
A protein called angiopoietin-2 (ANGPT2) can both inhibit and encourage blood vessel changes critical for sepsis, a leading cause of hospital deaths worldwide, a new study led by UT Southwestern Medical Center researchers shows.
Children’s Research Institute at UT Southwestern scientists identify feature of aggressive non-small cell lung cancer
In localized non-small cell lung cancer (NSCLC), a tumor’s ability to use carbon from glucose to feed the tricarboxylic acid (TCA) cycle predicts cancer spread beyond the lung, months to years before metastases are clinically apparent. According to this new research from Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Cancer Discovery, tumors with this metabolic activity result in early patient death.
UTSW Research: COVID-19’s effects, brain-computer interfaces, and more
People with multiple sclerosis (MS) are at an increased risk of infection and infection-related hospitalizations, but a study published in Neurology found that being infected with COVID-19 did not significantly affect the course of the disease.
CRI scientists link hematopoietic cell transplant deaths to beta-blocker use
Patients can die if they take certain previously prescribed beta-blockers during a hematopoietic cell transplant due to suppressed signals from nerves that promote bone marrow regeneration.
New findings expand genetic knowledge of autism underpinnings
Hundreds of novel genetic variants across an ancestrally diverse cohort of 195 families, including 222 people with autism spectrum disorder (ASD), have been identified by researchers at UT Southwestern Medical Center, expanding the catalog of known mutations associated with ASD.
CRI’s Gerta Hoxhaj, Ph.D., named TAMEST 2025 Mary Beth Maddox Award and Lectureship recipient
Gerta Hoxhaj, Ph.D., Assistant Professor in Children’s Medical Center Research Institute at UT Southwestern (CRI), is the recipient of the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST) 2025 Mary Beth Maddox Award and Lectureship for her research in cancer metabolism.