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– A “clot-busting” drug recently approved to treat acute ischemic strokes (AIS) that can be delivered quickly works as well as a decades-old medication used by most hospitals in the U.S. and could hold significant advantages for some patients, a study led by a UT Southwestern Medical Center researcher shows. The findings, published in JAMA Network Open, could encourage more hospitals to use the newer drug, tenecteplase.

A molecule called glial fibrillary acidic protein (GFAP) rose significantly in the blood of patients who underwent high-intensity focused ultrasound (HIFU), a procedure that is used to treat tremors and causes damage similar to a small stroke, UT Southwestern Medical Center scientists discovered in a new study. Their findings, published in Brain Communications, reveal a potential biomarker for stroke and could eventually lead to blood tests that quickly diagnose brain injuries.

Researchers at UT Southwestern Medical Center have linked blindness in animal models to a brain-wide cellular stress response that’s a common risk factor for dementia. Their findings, published in Nature Communications, could help explain the connection between vision or hearing loss and dementia.

Using a powerful microscopy technique, a team led by researchers at UT Southwestern Medical Center has gained insights into how the body uses vitamin K, an essential nutrient that plays a pivotal role in blood clotting and other physiological functions.

Researchers at UT Southwestern Medical Center have developed a novel artificial intelligence (AI) model that analyzes the spatial arrangement of cells in tissue samples.

Jinming Gao, Ph.D., Professor of Biomedical Engineering, Cell Biology, Otolaryngology – Head and Neck Surgery, and Pharmacology at UT Southwestern Medical Center, has been selected as a fellow of the National Academy of Inventors (NAI) in recognition of his efforts to develop innovative nanotechnology platforms to improve cancer diagnosis and treatment.

Tailoring prescriptions individually to a patient’s needs after cesarean delivery can decrease opioid use while successfully managing post-surgical pain, according to a new study by researchers at UT Southwestern Medical Center. The change in protocol, detailed in a study published in the American Journal of Obstetrics and Gynecology, lessened the number of opioids released into the community by more than 90,000 tablets per year.

Despite the convenience of at-home screening tests for early detection of colorectal cancer (CRC), a study led by UT Southwestern Medical Center researchers examining more than a decade of patient data found that about 10% of the tests could not be processed, mostly due to patient error.

UT Southwestern Medical Center will lead a multi-institution effort to gather and assimilate information on the billions of sequences employed by immune receptors of the adaptive immune system.

A two-step screening protocol that combines clinical risk assessment with biomarker testing can more effectively identify which patients with Type 2 diabetes need medication to prevent heart failure, according to a study led by UT Southwestern Medical Center researchers.