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For patients with estrogen receptor (ER)-positive breast cancer, development of the so-called Y537S mutation signals that their disease has taken an aggressive course and may become resistant to endocrine therapy.

UT Southwestern Medical Center is one of just 15 surgical centers in the world using next-generation augmented reality (AR) in the operating room for shoulder arthroplasty.

A gene called Npas4, already known to play a key role in balancing excitatory and inhibitory inputs in brain cells, appears to also be a master timekeeper for the brain’s circadian clock, new research led by UT Southwestern scientists suggests.

UT Southwestern faculty have discovered what appears to be an Achilles’ heel in ovarian cancers, as well as new biomarkers that could point to which patients are the best candidates for possible new treatments.

UT Southwestern Medical Center ranks among the top 25 hospitals nationally in eight specialties ranging from brain to heart to cancer care, according to the latest U.S. News & World Report’s annual Best Hospitals report.

Researchers at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered a new metabolic vulnerability in a highly aggressive form of non-small cell lung cancer (NSCLC).

UT Southwestern Medical Center was recognized as the top health care employer in Texas, one of the top 10 employers across all industries in the state, and among the nation’s Best-in-State employers nationally by Forbes/Statista.

In southern Dallas County, UT Southwestern researchers are creating groundbreaking initiatives that are giving access to postpartum care to thousands of new mothers. The bold new study, Improving Maternal Postpartum Access to Care through Telemedicine (IMPACT), is exploring how virtual care and smartphone-based education can transform maternal health outcomes.

Lowering iron content in fat cells prevented mice fed a high-fat diet from gaining excess weight and developing associated health problems by limiting the amount of lipids absorbed by the intestines

Using a laser for a rare brain surgery to treat drop seizures, which cause a child with epilepsy to suddenly fall, holds some advantages over a traditional open craniotomy