Review Board Committee

UT Southwestern Institutional Review Board (IRB) has four IRB review board committees. The requirements for IRB review board membership are addressed in the HHS regulations at 45 CFR 46.107 [Note: 45 CFR 46.304 requires a specialized IRB composition when research involving prisoners is being reviewed, including the presence of a prisoner representative].

An IRB review board must:

i. Have at least five members with varying backgrounds to promote complete and adequate review of the research activities commonly conducted by the institution.
ii. Make every nondiscriminatory effort to ensure that the membership is not composed of entirely men or entirely women.
iii. Include at least one member whose primary concerns are in scientific areas and at least one member whose primary concerns are in nonscientific areas.
iv. Include at least one member who is not otherwise affiliated with the institution and who is not part of the immediate family of a person who is affiliated with the institution.
v. Not allow any member to participate in the initial or continuing review of any project in which the member has a conflicting interest, except to provide information requested by the IRB. Please see the regulations at 45 CFR 46.107 for complete information on all of the required qualifications to properly compose an IRB.