The Cyclotron and Radiochemistry Facility was established to enable the development of a comprehensive Translational Molecular Imaging Program (TMIP) at UT Southwestern by providing a variety of existing, investigational, and novel PET radiotracers for both preclinical and clinical studies.

With the goal to serve the needs of cancer research projects, in particular those funded by CPRIT, NIH, DOD/DOE, and other state/federal funding agencies, we have organized the users into six groups. Among them, four groups (A – D) represent scientific research programs currently active in the NCI-designated Harold C. Simmons Comprehensive Cancer Center at UT Southwestern.

Given the traditional research strengths of faculty at UT Southwestern and the importance of metabolism in cancer, a fifth group of users (group E) was identified with a research focus on intermediary metabolism studies of cancer. In light of the financial sustainability of such a cyclotron facility at an academic institution, we have also been serving the research needs of non-cancer projects that focus on other diseases (group F).

Given the fact that currently no other academic institution in the North/Central Texas region has a cyclotron facility, we also provide cancer investigators at our partner institutions in North Texas with cyclotron-produced radiotracers and PET imaging as necessary.

User Groups:

• Cancer Cell Networks (user group A)
• Chemistry and Cancer (user group B)
• Development and Cancer (user group C)
• Molecular Therapeutics of Cancer (user group D)
• Intermediary Metabolism and Cancer (user group E)
• Other Diseases (user group F)