2026 Article Archive
Scientists discover metabolite fueling aggressive brain tumor growth
Virtually all high-grade, aggressive gliomas in adults accumulate massive amounts of a metabolite called guanidinoacetate (GAA) that overstimulates nearby neurons and promotes tumor growth, according to new research from scientists at Children’s Medical Center Research Institute at UT Southwestern (CRI) published today in Cell.
Masashi Yanagisawa, M.D., Ph.D., receives Lasker Award for discovery that transformed narcolepsy care
The Lasker Foundation has announced that UT Southwestern sleep researcher Masashi Yanagisawa, M.D., Ph.D., is a recipient of the 2026 Albert Lasker Basic Medical Research Award for his discovery of orexin, a brain peptide that maintains wakefulness, and demonstration that the absence of its action is responsible for narcolepsy, a profound disorder of sleep.
Brain signaling mechanism may explain clozapine weight gain
Researchers at UT Southwestern Medical Center have identified a key brain signaling pathway that appears to drive the substantial weight gain often associated with clozapine, a widely used antipsychotic medication.
Protein linked to immune response against tuberculosis
Researchers at UT Southwestern Medical Center have identified a protein that helps the immune system respond to tuberculosis (TB), one of the world's leading infectious diseases.
Brain activity discovery could transform Parkinson’s treatment
Researchers at UT Southwestern Medical Center studying Parkinson’s disease have discovered a previously unrecognized sequence of abnormal activity across multiple regions of the brain, providing a new level of understanding that could improve treatment options.
New framework developed for treating liver cancer
A multidisciplinary team co-led by Amit Singal, M.D., Chief of Hepatology and Director of the Liver Tumor Program in the Division of Digestive and Liver Diseases at UT Southwestern Medical Center, has developed new treatment recommendations for liver cancer that incorporate the latest research and an expanding range of therapeutic options.
Study of living brain tissue reveals how Parkinson’s treatment works
A team co-led by UT Southwestern Medical Center researchers has identified cellular and molecular mechanisms that could explain the effects of deep brain stimulation (DBS).
New research center set to explore treatments for Alzheimer’s
Since launching in April, the North Texas Alzheimer’s Disease Research Center (NT-ADRC) based at UT Southwestern Medical Center has quickly established the foundation needed to support cutting-edge research into Alzheimer’s and related dementias.
A decade of excellence: UTSW is DFW’s top hospital for 10th year in a row
For the 10th consecutive year, UT Southwestern Medical Center has been named the No. 1 hospital in Dallas-Fort Worth by U.S. News & World Report. Additionally, UTSW ranks among the nation’s top hospitals for care in 11 specialties – the most of any hospital in Texas – in the annual U.S. News Best Hospitals list released today.
How to boost enrollment of Black, Hispanic patients in pediatric clinical trials
While Black and Hispanic families are enthusiastic about research participation, other provider and systems-focused factors may influence their involvement in pediatric oncology clinical trials, a new UT Southwestern Medical Center-led study has found.