Instruments and Locations
Small Animal Irradiation Platforms
PCRCF has two state-of-the-art small animal irradiators to deliver high-throughput, high-precision radiation experiments under image guidance:
- X-RAD 225Cx from Precision X-Ray Irradiation, Inc (NE3, outside animal facility barrier).
- SAARP from Xstrahl Inc. (NB3.206, behind animal facility barrier.) Currently on order and will be operational December 2019.
PCRCF has one X-ray irradiator to deliver high-dose-rate X-ray radiation to small animals or biological specimens:
- X-RAD 320 from Precision X-ray Irradiation Inc. (NG2.310, behind animal facility barrier).
PCRCF has the following imaging devices to meet different needs:
- MRS 3017 MRI scanner with a 3T magnet field and 17 cm bore size (NB3.206, behind animal facility barrier). Currently on order and will be operational in June 2019.
- X-RAD 225Cx system is equipped with a cone-beam CT for image-guided radiation therapy.
- SAARP system is equipped with both cone-beam CT and micro-CT systems for imaged-guided radiation therapy, as well as respiratory gating assistance for precise radiation therapy.
- Ami HTX Optical Imaging System specifications:
- Bioluminescent imaging
- Fluorescent imaging
- X-ray imaging
- High throughput
- Pure LED illumination
- 100X light intensity on specimen
- 10 LED wavelengths from 430nm to 745nm
- 10 filters included from 530nm to 790 nm
- Solid state cooled CCD camera (–90C)
- High-performance imager
- CCD camera with back illumination
- Ultra-wide category leading 25cm x 17cm optical FOV
- X-ray FOV is 25 x 15 cm
- Up to 40kV maximum X-ray energy
- Molecubes, a new addition to the Core Facility, is coming in January 2023. Details in the image gallery.
A computational facility will be set up to offer accurate dosimetry and treatment planning via advanced Monte Carlo simulation tools on a high-performance GPU platform.
A quality assurance program has been established that includes physics personnel performing quality assurance activities on all of the equipment on a weekly, quarterly, and annual basis to validate and maintain their geometric and dosimetric accuracy. Dosimetric measurements using devices with accuracy traceable to national standards ensure dosimetric uncertainty of our irradiators to ±3%.