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UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes – an ability known as phenotypic plasticity.

Two studies led by the Chahrour Lab at UT Southwestern Medical Center shed new light on genes associated with autism spectrum disorder (ASD), the neurodevelopmental disease characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors.

An RNA-modifying enzyme linked to cancer and neurological disorders selects its targets by recognizing specific RNA shapes and sequences, according to a study by UT Southwestern Medical Center researchers.

The National Cancer Institute (NCI) has renewed UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center Kidney Cancer Program (KCP) Specialized Program of Research Excellence (SPORE) award.

A new study by UT Southwestern’s Simmons Cancer Center scientists suggests that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that fight cancer.

Following Enhanced Recovery After Surgery (ERAS) protocols designed to minimize surgical stress results in improved patient recovery and satisfaction, reduced postoperative complications, and shorter hospital stays, according to a review of ERAS programs in minimally invasive gynecologic surgery by UT Southwestern researchers.

Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern researchers reported.

UTSW study suggests combination therapy might help prostate cancer patients overcome resistance to current treatments.

Leveraging its broad expertise in biomedical informatics, data sciences, and clinical sciences, UT Southwestern Medical Center is aggressively expanding its involvement in clinical informatics, which aims to harness the power of big data to improve patient care and public health.

An enzyme called Fic, whose biochemical role was discovered at UT Southwestern more than a dozen years ago, appears to play a crucial part in guiding the cellular response to stress, a new study suggests.