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An experimental antibody treatment that binds to a protein known as PCDH7 shrank tumors in preclinical models of non-small cell lung cancer (NSCLC), even those resistant to a targeted therapy, a study led by UT Southwestern Medical Center researchers showed.

UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes – an ability known as phenotypic plasticity.

The widespread use of electronic patient portals to provide quick access to test results presents healthcare professionals with an important challenge: How should new cancer diagnoses be communicated?

When Haley and Zachary Sanders had their first baby, Rowan, and learned she had multiple heart defects, they were shattered. They never imagined technology borrowed from video games would help save their baby’s life.

Electronic Health Record vendors in the $31.5 billion industry should not be permitted to provide continuing medical education activities and presentations to physicians to avoid bias, researchers argue in a perspective article for the Association of American Medical Colleges’ journal, Academic Medicine.

Loss of an enzyme necessary for a process called lipoylation disrupts the way cancer cells copy their DNA, increasing their vulnerability to a class of anticancer drugs known as PARP inhibitors, a study led by UT Southwestern Medical Center researchers shows.

The American Heart Association 2030 Impact Goals aim to help all people live healthier for more years of their life.

Qing Zhang, Ph.D., and his colleagues identified a possible way to treat tumors while sparing nearby healthy tissue.

Two studies led by the Chahrour Lab at UT Southwestern Medical Center shed new light on genes associated with autism spectrum disorder (ASD), the neurodevelopmental disease characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors.

Much like human beings, songbirds learn how to vocalize from their parents. Males imitate songs from their fathers and then sing to attract mates. Although the circuits that generate human speech are more complicated to decipher, the brains of songbirds offer a viable model for better understanding how humans learn to speak and what goes wrong in communication disorders such as autism.