Publications

Dr. Steven Gray

Intravitreal gene therapy protects against retinal dysfunction and degeneration in sheep with CLN5 Batten disease

Murray, S. J., Russell, K. N., Melzer, T. R., Gray, S. J., Heap, S. J., Palmer, D. N. & Mitchell, N. L., Jun 2021, In: Experimental Eye Research. 207, 108600. PubMed

 
Dr. Joseph Hill

Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury

Xie M, Cho GW, Kong Y, Li DL, Altamirano F, Luo X, Morales CR, Jiang N, Schiattarella GG, May HI, Medina J, Shelton JM, Ferdous A, Gillette TG, Hill JA Circ Res. 2021 Jun 11 PubMed

 
Dr. Joshua Mendell


NORAD-induced Pumilio phase separation is required for genome stability

Elguindy MM, Mendell JT. Nature. 2021 Jun 9. PubMed

 
Dr. Sean Morrison

New guidelines for stem cell and embryo research from the ISSCR

Anthony E, Lovell-Badge R, Morrison SJ. Cell Stem Cell. 2021 Jun 3;28(6):991-992. PubMed

 
Dr. Thomas Carroll

Deletion of Lats1/2 in adult kidney epithelia leads to renal cell carcinoma

Carter P, Schnell U, Chaney C, Tong B, Pan X, Ye J, Mernaugh G, Cotton JL, Margulis V, Mao J, Zent R, Evers BM, Kapur P, Carroll TJ. J Clin Invest. 2021 Jun 1;131(11):e144108. PubMed

 
Dr. Jane Johnson

ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer

Olsen RR, Ireland AS, Kastner DW, Groves SM, Spainhower KB, Pozo K, Kelenis DP, Whitney CP, Guthrie MR, Wait SJ, Soltero D, Witt BL, Quaranta V, Johnson JE, Oliver TG. Circ Res. 2021 May 28;128(11):1629-1641. PubMed

 
Dr. Joseph Hill

NAD+ Repletion Reverses Heart Failure With Preserved Ejection Fraction

Tong D, Schiattarella GG, Jiang N, Altamirano F, Szweda PA, Elnwasany A, Lee DI, Yoo H, Kass DA, Szweda LI, Lavandero S, Verdin E, Gillette TG, Hill JA. 2021 May 28;128(11):1629-1641. PubMed

 
Dr. Gary Hon

FBA: feature barcoding analysis for single cell RNA-Seq

Duan J, Hon G. Bioinformatics. 2021 May 17:btab375. PubMed

 
Dr. Thomas Carroll

Vascular deficiencies in renal organoids and ex vivo kidney organogenesis

Ryan AR, England AR, Chaney CP, Cowdin MA, Hiltabidle M, Daniel E, Gupta AK, Oxburgh L, Carroll TJ, Cleaver O. Dev Biol. 2021 May 15;477:98-116. PubMed

 
Dr. Jenna Jewell

ArfGAP1 inhibits mTORC1 lysosomal localization and activation

Meng D, Yang Q, Melick CH, Park BC, Hsieh TS, Curukovic A, Jeong MH, Zhang J, James NG, Jewell JL. EMBO J. 2021 May 14:e106412. PubMed

 
Dr. Michael Buszczak

Variants in GCNA, X-linked germ-cell genome integrity gene, identified in men with primary spermatogenic failure

Hardy JJ, Wyrwoll MJ, Mcfadden W, Malcher A, Rotte N, Pollock NC, Munyoki S, Veroli MV, Houston BJ, Xavier MJ, Kasak L, Punab M, Laan M, Kliesch S, Schlegel P, Jaffe T, Hwang K, Vukina J, Brieño-Enríquez MA, Orwig K, Yanowitz J, Buszczak M, Veltman JA, Oud M, Nagirnaja L, Olszewska M, O'Bryan MK, Conrad DF, Kurpisz M, Tüttelmann F, Yatsenko AN; GEMINI Consortium. Hum Genet. 2021 May 7. PubMed

 
Dr. Kathryn O'Donnell

Translational Control of Immune Evasion in Cancer.

Suresh S, O'Donnell KA. Trends Cancer. 2021 May 7 :S2405-8033(21)00082-0. PubMed

 
Dr. Kim Orth

Urinary prostaglandin E2 as a biomarker for recurrent UTI in postmenopausal women.

Ebrahimzadeh T, Kuprasertkul A, Neugent ML, Lutz KC, Fuentes JL, Gadhvi J, Khan F, Zhang C, Sharon BM, Orth K, Li Q, Zimmern PE, De Nisco NJ. Life Sci Alliance. 2021 May 6;4(7):e202000948. PubMed

 
Dr. Jenna Jewell

RAG-ulating mTORC1 with amino acids.

Jewell JL. Nat Rev Mol Cell Biol. 2021 May 4. PubMed

 
Dr. Eric Olson

The histone reader PHF7 cooperates with the SWI/SNF complex at cardiac super enhancers to promote direct reprogramming

Garry, GA, Bezprozvannaya, S, Chen, K, Zhou, H, Hashimoto, H, Morales, MG, Liu, N, Bassel-Duby, R & Olson, EN. 3 May 2021, In: Nature cell biology. 23, 5, p. 467-475 9 p. PubMed

 
Dr. Hao Zhu

High Neutrophil–Lymphocyte Ratio and Delta Neutrophil–Lymphocyte Ratio Are Associated with Increased Mortality in Patients with Hepatocellular Cancer.

Rich, NE, Parvathaneni, A, Sen, A, Odewole, M, Arroyo, A, Mufti, AR, Kerr, TA, Grant, L, Tujios, SR, Mayo, MJ, Lee, WM, Yang, JD, Yokoo, T, Gopal, P, Hoshida, Y, Zhu, H, Yopp, AC, Marrero, JA & Singal, AG, 3 May 2021, In: Digestive Diseases and Sciences. PubMed

 
Dr. Benjamin Levi

High Frequency Spectral Ultrasound Imaging Detects Early Heterotopic Ossification in Rodents.

Edwards NJ, Hobson E, Dey D, Rhodes A, Overmann A, Hoyt B, Walsh SA, Pagani CA, Strong AL, Hespe GE, Padmanabhan KR, Huber A, Deng C, Davis TA, Levi B. Stem Cells Dev. 2021 May 1;30(9):473-484. PubMed

 
Dr. Yichen Ding

Real-time volumetric reconstruction of biological dynamics with light-field microscopy and deep learning.

Wang Z, Zhu L, Zhang H, Li G, Yi C, Li Y, Yang Y, Ding Y, Zhen M, Gao S, Hsiai TK, Fei P. Nat Methods. 2021 May;18(5):551-556. PubMed

 
Dr. Eric Olson

Precise correction of Duchenne muscular dystrophy exon deletion mutations by base and prime editing

Chemello, F, Chai, AC, Li, H, Rodriguez-Caycedo, C, Sanchez-Ortiz, E, Atmanli, A, Mireault, AA, Liu, N, Bassel-Duby, R & Olson, EN.30 Apr 2021, In: Science Advances. 7, 18, eabg4910. PubMed

 
Dr. Carol Wise

Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice

Rios, J. J., Denton, K., Russell, J., Kozlitina, J., Ferreira, C. R., Lewanda, A. F., Mayfield, J. E., Moresco, E., Ludwig, S., Tang, M., Li, X., Lyon, S., Khanshour, A., Paria, N., Khalid, A., Li, Y., Xie, X., Feng, J. Q., Xu, Q., Lu, Y. & 3 others, , 27 Apr 2021, In: Journal of Bone and Mineral Research. PubMed