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Microscope overview

Explore the imaging systems available through the QLMC. Select Technical details on any card for additional specifications.Color legend: Super-resolution Confocal Widefield fluorescence Holotomography Stereo / dissecting

Abberior Facility Line STED microscope

Abberior Facility Line STED

Super-resolution · Inverted

3D STED super-resolution microscope with adaptive illumination and adaptive optics for imaging deeper specimens.

Manufacturer: Abberior Instruments
Location: ND5.760
Internal rate: $25/hour
$25 autonomous; $65 assisted

Key capabilities: Confocal; 2D STED; 3D STED; Adaptive illumination; Adaptive optics; RESCue; Tiling

Technical details ▾
Imaging modalities Confocal; 2D STED; 3D STED
Super-resolution STED
Specimen types Live cells; Fixed cells; Tissue.
Sample formats Slides; 35 mm dishes
Excitation 405; 485; 561; 640; depletion: 595, 775
Environmental control Live-cell: Yes; temperature: Yes; CO₂: Yes; humidity: Yes
Special capabilities Adaptive illumination; Adaptive optics; RESCue; DyMIN; MINFIELD; Automated z-stacks; FRET; Tiling
Objectives 60x/1.42 oil; 60x/1.20 water; 60x/1.30 silicon
Recommended applications 2D STED; 3D STED; Organoids super-resolution.
Leica Stellaris Falcon 8 microscope

Leica Stellaris Falcon 8

Confocal · Inverted

Super-resolution

Inverted laser-scanning confocal microscope with integrated Falcon 8 FLIM and TauSense technology.

Manufacturer: Leica Microsystems
Location: NL5.120R
Internal rate: $40/hour
Half price outside internal peak hours

Key capabilities: Laser-scanning confocal; FLIM; FCS; TauSense; Spectral imaging; FLIM-FRET; FRAP

Technical details ▾
Imaging modalities Laser-scanning confocal; FCS; FLIM; Spectral imaging
Super-resolution Lightening
Specimen types Immunofluorescent cell cultures; Tissue sections, Organoids; Live cells; Fixed cells
Sample formats Slides; 35 mm dishes; Multi-well chambers; Multi-well plates
Excitation 405 plus 440–790 (tunable Wight Light Laser)
Detectors 5 detectors:  3 HyD S + 1 HyD X + 1 HyD R; detection range 400–850 nm
Environmental control Live-cell: Yes; temperature: Yes; CO₂: Yes; humidity: Yes
Special capabilities FLIM; TauSense; Spectral imaging; Spectral unmixing; FLIM-FRET; FRAP; FRET; FCS; Photoablation; Photoactivation; Uncaging; infra-red imaging; Resonant scanning; Simultaneous multi-channel acquisition; Fast z-stacks; Tiling; Focus stabilization
Objectives 10x\0.4 air; 20x\0.75 air; 40x\0.95 air; 40x\1.3 oil; 63x\1.4 oil
Recommended applications Live-cell imaging; Fixed-cell imaging; Tissue; Fluorescence lifetime imaging; Spectral imaging
Nikon CSU-W1 Dual Camera microscope

Nikon CSU-W1 Dual Camera

Confocal · Inverted

Fast inverted spinning-disk confocal microscope with two sCMOS cameras for simultaneous two-channel imaging.

Manufacturer: Nikon
Location: K1.228
Internal rate: $40/hour
Half price outside internal peak hours

Key capabilities: Spinning-disk confocal; Widefield fluorescence; Simultaneous two-channel acquisition; Fast z-stacks; Tiling; Focus stabilization

Technical details ▾
Imaging modalities Spinning-disk confocal; Widefield fluorescence; Brightfield
Specimen types Immunofluorescent cell cultures; Tissue sections, Organoids; Live cells; Fixed cells
Sample formats Slides; 35 mm dishes; Multi-well chambers; Multi-well plates
Excitation 405; 445; 488; 514; 561; 594; 640
Detectors sCMOS
Cameras 2 × Hamamatsu ORCA-Fusion BT
Transmitted light Phase contrast; DIC; Brightfield
Environmental control Live-cell: Yes; temperature: Yes; CO₂: Yes; humidity: Yes
Special capabilities Simultaneous two-channel acquisition; Fast z-stacks; Automated z-stacks; FRET; Tiling; Focus stabilization; Up to 100 frames/s
Objectives 4x\0.2 air; 10x\0.45 air; 20x\0.8 air; 40x\1.3 oil; 60x1.42 oil; 100x\1.45 oil
Recommended applications Fast live-cell imaging; Rapid cellular dynamics; Simultaneous two-color imaging; Fixed-cell imaging; fast multicolor z-stacks
Nikon CSU-W1 SoRa microscope

Nikon CSU-W1 SoRa

Confocal · Inverted

Super-resolution

Fast spinning-disk confocal microscope with SoRa super-resolution and a dedicated FRAP module.

Manufacturer: Nikon
Location: NL5.120R
Internal rate: $40/hour
Half price outside internal peak hours

Key capabilities: Spinning-disk confocal; Widefield fluorescence; FRAP; SoRa; Photoablation; Photoactivation

Technical details ▾
Imaging modalities Spinning-disk confocal; Widefield fluorescence; Brightfield; Polarized light
Super-resolution SoRa
Specimen types Immunofluorescent cell cultures; Tissue sections, Organoids; Live cells; Fixed cells
Sample formats Slides; 35 mm dishes; Multi-well chambers; Multi-well plates
Excitation 405; 445; 488; 514; 561; 640; FRAP: 405, 473, 561
Detectors sCMOS
Cameras Hamamatsu ORCA-Fusion
Transmitted light Phase contrast; DIC; Brightfield; Polarized light
Environmental control Live-cell: Yes; temperature: Yes; CO₂: Yes; humidity: Yes
Special capabilities SoRa; FRAP; FRET; Photoablation; Photoactivation; Uncaging; Fast z-stacks; Automated z-stacks; Tiling; Focus stabilization; Up to 100 frames/s
Objectives 4x\0.13 air; 10x\0.3 air; 20x\0.75 air; 40x\1.3 oil; 60x\1.4 oil; 100x1.45 oil
Recommended applications Fast live-cell imaging; Rapid cellular dynamics; Fast FRAP recoveries; Fixed-cell imaging; fast multicolor z-stacks
Nikon Ti Widefield Epi-scope microscope

Nikon Ti Widefield Epi-scope

Epi fluorescence · Inverted

Inverted widefield microscope with monochrome fluorescence and true-color cameras for fluorescence, histology, and polarized-light imaging.

Manufacturer: Nikon
Location: NL5.120R
Internal rate: $25/hour
Standard internal rate

Key capabilities: Widefield fluorescence; Brightfield; Histology imaging; Polarized light; Focus stabilization

Technical details ▾
Imaging modalities Widefield fluorescence; Brightfield; Histology imaging; Polarized light
Specimen types Live cells; Fixed cells; Histology specimens;
Sample formats Slides; 35 mm dishes; Multi-well chambers; Multi-well plates
Excitation Filter centers: 350; 405; 445; 488; 514; 555; 645
Detectors sCMOS; Color CMOS
Cameras Andor Zyla 5.5 sCMOS; Teledyne Infinity3-6UR color
Transmitted light Phase contrast; DIC; Brightfield; Polarized light
Environmental control Live-cell: Yes; temperature: Yes; CO₂: Yes; humidity: Yes
Special capabilities z-stacks; Focus stabilization; True-color imaging
Objectives 4x\0.13 air; 10x\0.3 air; 20x\0.75 air; 40x\0.95 air; 60x\1.4 oil; 100x1.45 oil
Recommended applications Routine fluorescence; Histological stains; Polarized light; Multi-position imaging; Live-cell imaging
OMX SR microscope

DeltaVision OMX SR

Super-resolution · Inverted

Multimodal super-resolution system supporting 3D SIM, TIRF SIM, PALM/STORM, and ring TIRF.

Manufacturer: GE Healthcare
Location: NL5.120R
Internal rate: $45/hour
$45 autonomous; $65 assisted

Key capabilities: 3D SIM; TIRF SIM; 2D PALM/STORM; Ring TIRF

Technical details ▾
Imaging modalities 3D SIM; TIRF SIM; 2D PALM/STORM; Ring TIRF
Super-resolution SIM; PALM; STORM
Specimen types Live cells; Fixed cells
Sample formats Slides; 35 mm dishes
Excitation 405; 488; 561; 640
Detectors 4 x sCMOS
Environmental control Live-cell: Yes; temperature: Yes; CO₂: Yes; humidity: Yes
Special capabilities Deconvolution; Nanopositioning motorized xyz stage; SIM; PALM/STORM
Recommended applications 3D structured illumination; Single-molecule localization; TIRF; Live-cell super-resolution
Tomocube HT-X1 Plus microscope

Tomocube HT-X1 Plus

Holotomography · Inverted

Label-free 3D holotomography system with fluorescence imaging for live cells, organoids, and tissue.

Manufacturer: Tomocube
Location: NL5.120S
Internal rate: $30/hour
Standard internal rate

Key capabilities: Holotomography: label-free imaging; Widefield fluorescence; 3D refractive-index mapping; Focus stabilization

Technical details ▾
Imaging modalities Holotomography; Widefield fluorescence; Brightfield
Specimen types Live cells; Organoids
Sample formats Slides; 35 mm dishes; 50 mm dishes; Multi-well chambers; Microtiter plates
Excitation LEDs: 405; 488; 561; 640
Detectors 20 MP CMOS
Cameras sCmos
Transmitted light Label-free refractive-index imaging
Environmental control Live-cell: Yes; temperature: Yes; CO₂: Yes; humidity: Yes
Special capabilities 3D refractive-index mapping; Label-free imaging; Focus stabilization
Objectives 40x/0.95 air
Recommended applications Label-free live-cell imaging; Organoids; Tissue; Correlative fluorescence and holotomography
Zeiss LSM 780 Inverted microscope

Zeiss LSM780 with 2-P

Confocal · Inverted

Inverted spectral confocal and multiphoton microscope with live-cell incubation.

Manufacturer: Zeiss
Location: NL5.120N
Internal rate: $40/hour
Half price outside internal peak hours

Key capabilities: Laser-scanning confocal; Multiphoton; Spectral imaging; SHG; FRAP; Photoablation, Photoactivation

Technical details ▾
Imaging modalities Laser-scanning confocal; Multiphoton; Spectral imaging; SHG
Specimen types Immunofluorescent cell cultures; Tissue sections, Organoids; Live cells; Fixed cells
Sample formats Slides; 35 mm dishes; Multi-well chambers; Multi-well plates
Excitation 405; 458; 488; 514; 561; 594; 633
Multiphoton range 690–1040nm
Detectors 32-channel GaAsP PMT Array; 2 Standard Multi-Alkali (MA) PMTs; 2 non-descanned detectors
Environmental control Live-cell: Yes; temperature: Yes; CO₂: Yes; humidity: Yes
Special capabilities Simultaneous multi-channel acquisition; Focus stabilization; Automated z-stacks; Tiling; FRAP; Photoablation; Photoactivation; Uncaging; Spectral unmixing; FRET; SHG.
Objectives 10x/0.3; 20x/0.8; 25x/0.8; 40x/1.4; 63x/1.4
Recommended applications Confocal imaging; Live-cell imaging; Fixed-cell imaging; Multiphoton imaging; Deep-Tissue, Organoids imaging; FRET; Spectral unmixing; SHG
Zeiss LSM 780 Upright microscope

Zeiss LSM780 upright with 2-P 

Confocal · Upright

Upright confocal and multiphoton microscope configured for organ culture, deep Tissue, Organoids, and whole-animal imaging.

Manufacturer: Zeiss
Location: ND5.740
Internal rate: $40/hour
Half price outside internal peak hours

Key capabilities: Laser-scanning confocal; Multiphoton; Spectral imaging; SHG; FRAP; Deep imaging; Motorized stage

Technical details ▾
Imaging modalities Laser-scanning confocal; Multiphoton; Spectral imaging; SHG
Specimen types Organ culture; Whole-animal preparations; Thick Tissue, Organoids
Excitation 405; 458; 488; 514; 561; 594; 633
Multiphoton range 690–1040 nm
Detectors

32-channel GaAsP PMT Array; 2 Standard Multi-Alkali (MA) PMTs; 2 non-descanned detectors

Environmental control Temperature: Yes
Special capabilities Deep imaging; FRAP; FRET; Photoablation; Photoactivation; Uncaging; Spectral unmixing; SHG; Simultaneous multi-channel acquisition; Automated z-stacks; Tiling
Objectives 10x/0.3; 10x/0.45; 20x/0.8; 20x/1.0; 32x/0.85; 40x/1.1; 40x/1.3; 63x/1.4
Recommended applications Organ culture; Whole-animal imaging; Deep-Tissue, Organoids imaging; Multiphoton imaging; SHG
Zeiss LSM 880 Airyscan microscope

Zeiss LSM880 Airyscan

Confocal · Inverted

Super-resolution

Inverted laser-scanning confocal microscope with 32-channel spectral detection and Airyscan super-resolution.

Manufacturer: Zeiss
Location: K1.224
Internal rate: $40/hour
Half price outside internal peak hours

Key capabilities: Laser-scanning confocal; Spectral imaging; FRAP; Photoablation; Photoactivation; Uncaging

Technical details ▾
Imaging modalities Laser-scanning confocal; Spectral imaging
Super-resolution Airyscan FAST
Specimen types Immunofluorescent cell cultures; Tissue sections, Organoids; Live cells; Fixed cells
Sample formats Slides; 35 mm dishes; Multi-well chambers; Multi-well plates
Excitation 405; 458; 488; 514; 561; 633
Detectors 32-channel GaAsP PMT Array; 2 Standard Multi-Alkali (MA) PMTs; Airyscan FAST detector
Environmental control Live-cell: Yes; temperature: Yes; CO₂: Yes; humidity: Yes
Special capabilities Simultaneous multi-channel acquisition; Focus stabilization; Automated z-stacks; Tiling; Airyscan; FRAP; Photoablation; Photoactivation; Uncaging; Spectral unmixing; FRET
Objectives 10x/0.3; 20x/0.8; 40x/1.1; 40x/1.4; 63x/1.4
Recommended applications Confocal imaging; Super-resolution confocal imaging; Live-cell imaging; Fixed-cell imaging;Tissue, Organoid; Spectral imaging
Zeiss LSM 880 Inverted microscope

Zeiss LSM880 with 2-P

Confocal · Inverted

Inverted spectral confocal and multiphoton microscope with FCS, live-cell incubation, and photomanipulation tools.

Manufacturer: Zeiss
Location: NL7.134A
Internal rate: $40/hour
Half price outside internal peak hours

Key capabilities: Laser-scanning confocal; Multiphoton; Spectral imaging; SHG; FCS; FRAP

Technical details ▾
Imaging modalities Laser-scanning confocal; Multiphoton; Spectral imaging; SHG; FCS
Specimen types Immunofluorescent cell cultures; Tissue sections, Organoids; Live cells; Fixed cells
Sample formats Slides; 35 mm dishes; Multi-well chambers; Multi-well plates
Excitation 405; 458; 488; 514; 561; 594; 633
Multiphoton range 690–1040
Detectors 32-channel GaAsP PMT spectral detector; Dual-channel non-descanned detector
Environmental control Live-cell: Yes; temperature: Yes; CO₂: Yes; humidity: Yes
Special capabilities FCS; FRAP; Photoablation; Photoactivation; Uncaging; Spectral unmixing; FRET; SHG; Simultaneous two-channel acquisition; Focus stabilization; Automated z-stacks; Tiling
Objectives 10x/0.3; 20x/0.8; 40x/1.2; 40x/1.4; 100x/1.4
Recommended applications Confocal imaging; Live-cell imaging; Fixed-cell imaging; Tissue, Organoid; Spectral imaging; Multiphoton imaging; Deep-Tissue, FCS; FRET; Spectral unmixing; SHG
Zeiss LSM 980 Airyscan 2 microscope

Zeiss LSM980 Airyscan 2

Confocal · Inverted

Super-resolution

Inverted spectral confocal microscope with Airyscan 2, FCS components, automated sample finding, and fast acquisition workflows.

Manufacturer: Zeiss
Location: NL5.120LA
Internal rate: $40/hour
Half price outside internal peak hours

Key capabilities: Laser-scanning confocal; Spectral imaging; FCS; Airyscan 2; FRAP

Technical details ▾
Imaging modalities Laser-scanning confocal; Spectral imaging; FCS
Super-resolution Airyscan 2
Specimen types Immunofluorescent cell cultures; Tissue sections, Organoids; Live cells, Fixed cells
Sample formats Slides; 35 mm dishes; Multi-well chambers; Multi-well plates
Excitation 405; 445; 488; 514; 561; 594; 639; 730
Detectors 32-channel GaAsP PMT spectral detector; 2-channel MA-PMT; T-PMT 2; Airyscan 2 detector
Cameras High-end epi-fluorescence camera
Transmitted light Transmitted-light detector
Environmental control Live-cell: Yes; temperature: Yes; CO₂: Yes; humidity: Yes
Special capabilities AI sample finder; Simultaneous multi-channel acquisition; Automated z-stacks; Tiling; Airyscan 2; FCS; FRAP; FRET; Photoablation; Photoactivation; Uncaging; Spectral unmixing; infra-red imaging; Focus stabilization
Objectives 10x/0.3 air; 20x/0.8 air; 25x/0.8 multi-immersion; 40x/1.2 water; 40x/1.3 oil; 63x/1.4 oil
Recommended applications Confocal imaging; Super-resolution confocal imaging; Live-cell imaging; Fixed-cell imaging; Tissue, Organoid; Spectral imaging; FCS; FRET; Spectral unmixing
Zeiss SteREO Discovery.V12 microscope

Zeiss SteREO Discovery V12

Stereo/dissecting · Stereo

Motorized fluorescence stereo microscope for screening and documenting whole-mount organisms, organs, Tissues, Organoids.

Manufacturer: Zeiss
Location: NL7.110M
Internal rate: $15/hour
Standard internal rate

Key capabilities: Fluorescence stereo microscopy; Brightfield; Extended-depth-of-field imaging; Automated z-stacks; Extended focus; Simultaneous GFP and transmitted-light imaging

Technical details ▾
Imaging modalities Fluorescence stereo microscopy; Brightfield; Extended-depth-of-field imaging
Specimen types Whole-mount flies; Worms; Mice; Organs; Tissue, Organoids
Excitation Filter sets: GFP; RFP; Cy5
Detectors Cooled monochrome camera; Color camera
Cameras Zeiss Axiocam MRm; Zeiss Axiocam MRc5
Transmitted light Brightfield; Transillumination; Gooseneck illumination
Environmental control Live-cell: No; temperature: No; CO₂: No; humidity: No
Special capabilities Automated z-stacks; Extended focus; Simultaneous GFP and transmitted-light imaging
Recommended applications Screening; Whole-mount specimens; Dissection; Documentation; Fluorescence screening