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2021 Article Archive

Same Difference: Two halves of the hippocampus have different gene activity


A study of gene activity in the brain’s hippocampus, led by UT Southwestern researchers, has identified marked differences between the region’s anterior and posterior portions.

How human cells and pathogenic shigella engage in battle


One member of a large protein family that is known to stop the spread of bacterial infections by prompting infected human cells to self-destruct appears to kill the infectious bacteria instead.

Experimental drug makes radiation therapy more effective, less damaging


An experimental drug that has shown promise in protecting healthy tissue from collateral damage caused by radiation therapy for cancer also appears to enhance radiation’s capacity to kill tumors.

UT Southwestern detects first reported B.1.617.2 (Indian) variant in North Texas


UT Southwestern Medical Center scientists have identified the first two cases of the B.1.617.2 (Indian origin) variant of COVID-19 infection in North Texas using next-generation sequencing technologies along with targeted PCR testing.

Scientists identify source of weight gain from antipsychotics


Scientists with UT Southwestern’s Peter O’Donnell Jr. Brain Institute have identified the molecular mechanism that can cause weight gain for those using a common antipsychotic medication.

UT Southwestern cancer researchers uncover antitumor mechanisms to help improve radiation therapy


An international team of cancer researchers has identified important mechanisms that activate antitumor immune response during radiation therapy

How Legionella makes itself at home


Scientists at UT Southwestern have discovered a key protein that helps the bacteria that causes Legionnaires’ disease to set up house in the cells of humans and other hosts.

Laser procedure offers advantages for rare pediatric epilepsy surgery


Using a laser for a rare brain surgery to treat drop seizures, which cause a child with epilepsy to suddenly fall, holds some advantages over a traditional open craniotomy

New gene editing strategies developed for Duchenne muscular dystrophy


UT Southwestern scientists successfully employed a new type of gene therapy to treat mice with Duchenne muscular dystrophy (DMD)

Quality improvement project boosts depression screening among cancer patients


Depression screening among cancer patients improved by 40 percent to cover more than 90 percent of patients under a quality improvement program launched by a multidisciplinary team at UT Southwestern Medical Center and Southwestern Health Resources.