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Protein coordinates responses to environmental stress

 

UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes – an ability known as phenotypic plasticity.

UTSW molecular biologist Benjamin Sabari, Ph.D., to receive Pershing Square Sohn Cancer Prize

 

Benjamin Sabari, Ph.D., Assistant Professor in the Cecil H. and Ida Green Center for Reproductive Biology Sciences and of Molecular Biology at UT Southwestern Medical Center, has been selected for a 2026 Pershing Square Sohn Cancer Prize.

Study links cancer metabolism to DNA replication errors

 

Loss of an enzyme necessary for a process called lipoylation disrupts the way cancer cells copy their DNA, increasing their vulnerability to a class of anticancer drugs known as PARP inhibitors, a study led by UT Southwestern Medical Center researchers shows.

UTSW Research: Kidney stones, cancer diagnoses, and brain injury

 

About 1 in 11 people in the U.S. experience urinary stone disease – more commonly known as kidney stones – according to the National Institute of Diabetes and Digestive and Kidney Diseases. Increasing fluid intake has long been recommended to decrease the risk of recurrence in those who develop this painful condition. However, studies have shown that maintaining high fluid intake can be difficult.

UT Southwestern biochemist Zhijian ‘James’ Chen receives 2026 Japan Prize

 

Zhijian “James” Chen, Ph.D., Professor of Molecular Biology at UT Southwestern Medical Center and one of the world’s top researchers on how the body’s immune system protects us against threats such as bacteria and viruses, has been awarded the 2026 Japan Prize in Life Sciences – one of the highest international honors for science and technology.