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New biosensor tracks down missing metabolite from childhood brain disorder

 

Scientists at Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered why babies born with a rare inborn error of metabolism, called GPT2 deficiency, suffer from severe neurological impairment, according to research published in Science.

Metabolites produced by gut bacteria may protect against fungal infection

 

A metabolic byproduct formed when gut bacteria break down dietary fiber appears to protect against dangerous fungal infections common in immunocompromised patients, a study led by UT Southwestern Medical Center researchers shows.

Adding drug to glioblastoma treatment may boost effectiveness

 

Treating glioblastoma with a class of drugs known as EGFR inhibitors made this cancer more sensitive to chemotherapy, suggests a study in preclinical models co-led by researchers at UT Southwestern Medical Center and the University of Alabama at Birmingham.

Gut bacteria boost immune system, help send vitamin A to T cells

 

Scientists at UT Southwestern Medical Center have discovered that gut bacteria help regulate the development of the body’s immune system by directing the movement of vitamin A through a previously unrecognized cellular network.

UT Southwestern ranked No. 1 in the world for healthcare research by Nature Index

 

UT Southwestern Medical Center is ranked No. 1 among healthcare institutions worldwide by Nature Index for publishing high-quality research in all subjects for the 12-month period that ended Feb. 28, 2026.