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Using UT Southwestern’s Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and cancer and crucial for Wnt signaling activation.

Imaging at near-atomic resolution of a key immune protein commonly known as STING has revealed a previously unrecognized binding site that appears to be pivotal for launching immune attacks, UT Southwestern scientists report in a new study.

An estimated one-quarter of adults in the U.S. have nonalcoholic fatty liver disease (NAFLD), an excess of fat in liver cells that can cause chronic inflammation and liver damage, increasing the risk of liver cancer.

For years, women recovering from cesarean section (C-section) deliveries have been given devices that let them, with a button, control the flow of opioid painkillers into their IV line.

A research team at UT Southwestern has been approved for a five-year, $7 million funding award from the Patient-Centered Outcomes Research Institute (PCORI).

UT Southwestern researchers have identified the molecular function of 87 inherited genetic variants that affect the risk of prostate cancer, and the majority appear to control the activity of genes located far away from the risk variants themselves.

Vaginal progesterone, a hormone treatment considered the standard of care for preventing preterm birth in at-risk pregnant women, may not be effective, according to UT Southwestern researchers.

Combat wounds to a soldier’s genital area are not as well understood as those to other parts of the body because of the intimate nature of the injuries.

The most common bacterial infection to occur after revision shoulder arthroplasty surgery can be diagnosed more accurately by considering how quickly samples of the microbe grow in hospital labs and the level of bacteria that grows, a study partly performed at UT Southwestern shows.

A new study by the Kidney Cancer Program (KCP) at UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center shows that highly focused radiation to isolated metastases that progress despite drug therapy can prolong drug use in kidney cancer patients, saving the few other drugs for treating kidney cancer for future use.