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Scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have identified the specialized environment, known as a niche, in the bone marrow where new bone and immune cells are produced.

A drug in clinical trials as a treatment for metabolic dysfunction-associated steatotic liver disease (MASLD) works with a one-two punch that shuts down triglyceride production and fatty acid synthesis in liver cells, UT Southwestern Medical Center researchers show in a new study.

UT Southwestern scientists may have identified a method of safely mimicking the weight-loss benefits of a plant compound that – despite its harmful side effects – hold critical answers to developing therapies for obesity.

Recently developed MRI techniques used to more precisely target a small area in the brain linked to Parkinson’s disease.

The activity of the parasite that causes malaria is driven by the parasite’s own inherent clock.

New national guidance for managing cholesterol and other blood lipids calls for earlier risk assessment, more personalized treatment, and renewed emphasis on long-term cardiovascular prevention – changes experts say could significantly reduce heart attacks and strokes over a lifetime.

Young patients from lower-income households in Texas may not be getting the most effective treatment for severe depression and suicidal thoughts, based on findings from researchers at UT Southwestern Medical Center.

People of South Asian descent make up one-quarter of the world’s population, but they account for 60% of cardiovascular disease cases. To help reduce the elevated risk of heart disease among South Asians living in North America, UT Southwestern Medical Center researchers joined global colleagues in developing comprehensive recommendations, published in the American Journal of Preventive Cardiology, for health care providers, patients, community members, and policymakers.

Researchers at UT Southwestern Medical Center are part of a team that developed a simple blood test that can detect developing heterotopic ossification (HO), the abnormal formation of bone in soft tissues after injury or surgery, weeks before it can be identified by traditional imaging.

Fewer concussions were reported among Texas high school athletes and students in urban and lower-income districts than in higher-income suburban districts despite larger enrollments, UT Southwestern Medical Center researchers found in a study.