CTSA KL2 Clinical and Translational Research Scholars

Accepting Applications

The KL2 Program is now accepting applications for the Sept. 2021 cohort. 

Application deadline: Aug. 1, 2021


Junior Faculty Investigators

This two-year program is designed for junior faculty who show great promise towards becoming successful independently funded clinical and translational science investigator, and their salary is supported partially by the KL2 grant.

We support six KL2 Scholars each year (3 new, 3 continuing). 


The KL2 Scholars Program is open to applicants from broad academic clinical and translational science disciplines. Those from diverse backgrounds including underrepresented minorities, disadvantaged, and disabled individuals are encouraged to apply.

To be considered, the applicant must:

  • Have a doctorate degree (e.g., M.D., Ph.D., D.O., among others)
  • Be a U.S. citizens or permanent resident as per NIH funding guidelines
  • Have a full faculty position at UT Southwestern, or our CTSA Hub Partner Institutions
  • Be committed to actively participate in the Program with 75% protected time for research for two consecutive years. (Note: individuals in certain surgical specialties may request permission for reduced research time pending NIH approval)
  • Have commitment from his/her sponsoring Department Chair or Center Director
  • Have prior clinical and translational research experience
  • Have a proposed research plan and identified mentors
  • Not be, nor have ever been, a principal investigator on an R01, R29, or subproject of a Program Project (P01), Center (P50, P60, U54) or mentored career development (K-series) grants or equivalent. R03 and R21 grants are permitted

Program Highlights

We expect that our Scholars will complete the program equipped with the skillset and passion to become successful, independent investigators who make contributions across the entire spectrum of clinical and translational research.

  • Two years with significant protected time to focus on research, publications and grant submissions.
  • Emphasis on mentoring. Scholars will develop a productive relation with a mentoring team that includes the primary research mentor(s), near-peer mentors, career mentors and Program Directors.
  • Customized Individual Career Development Plan. We will work with each Scholar and his/her mentors to develop a training portfolio uniquely tailored to meet the Scholar’s short and long-term goals.
  • The Scholar will:
  1. Develop clinical and translational research competencies through completion of required practica and core courses.
  2. Develop an individualized educational development plan created to address each Scholar’s unique educational needs and chose career path. Required and additional potential course. (*add link to table below)
  3. Develop critical thinking skills through small group discussions, interactive scientific presentations, and by completing written practica, manuscripts, and grant proposals.
  4. Formalized coaching on scientific communication.
  5. Develop leadership skills that are critically important for navigating clinical research process and leading multidisciplinary teams.
  6. Stepwise approach to development of NIH K award applications via practical coursework and writing workshops within the CTSA.
  7. Intensive training and career development for transitioning from K- type to R- type awards after program completion to become independent investigators and drive the clinical research transformation as envisioned by the Office of the Provost and Dean.

Program Faculty

The Scholars program has a broad base of outstanding faculty. It is co-directed by three senior faculty MPIs who have complementary strengths in the full spectrum of clinical and translational research and have long standing track records for mentoring and career development of junior research scientists. They are:

  • Helen Yin, Ph.D., Professor of Physiology, Associate Dean Office of Faculty Diversity & Development/Women’s Careers
  • Madhukar Trivedi, M.D., Professor of Psychiatry, and Director, Center for Depression Research and Clinical Care
  • Keith Argenbright, M.D., MMM, Professor of Population and Data Sciences, and Director of the Moncrief Cancer Institute

In addition, Dr. Heidi Jacobe, M.D., MSCS, Professor of Dermatology who was a KL2 Scholar graduate, will guide Scholars to design their customized curriculum/training plan.

Financial Support

KL2 Scholars will receive 75% of their UT Southwestern institutional base salary (up to the NIH cap of $199,300). This translates to $149,475 plus fringes for each Scholar per year.  

Additionally, they will receive a budget for associated coursework, research funds including pilot awards, and access to dedicated biostatistics and epidemiological support from the CTM Cores.

Scholars will be supported for two years; renewal of the second year of support will depend on a year-end review of the Scholar’s progress and adherence to deliverable milestones.

Affiliated Clinical Research Scholars Program

The Affiliated Clinical Research Scholars Program (ACRSP-faculty) is for faculty receiving prestigious UT Southwestern-funded clinical and translational research startup funds.

These include awardees of the Texas Health Resources (THR Scholars), DOCS, and specialty-specific Scholars programs. Eligibility requirements are similar to those of KL2 applicants, except that they should have non-KL2 salary support for their research programs. This cohort will have similar access to the CTSA core resources and educational programs, with the exception of their primary source of salary support. Please see RFA and apply using the same RFA and application form as for KL2 Scholars Program. Application deadline: August 1, 2021. Program Start: mid-Sept 2021.