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2021 Publications

  1. Li J, Canseco D, Wang Y, Vale G, Chaudhary J, Anwar A, Baniasadi H, Williams NS, Gopal P, Sutphin PD, McDonald JG, Putnam WC, Corbin IR. Assessing the safety of transarterial locoregional delivery of low-density lipoprotein docosahexaenoic acid nanoparticles to the rat liver. Eur J Pharm Biopharm. 2021 Jan;158:273-283. PMCID: PMC8121338.
  2. Marcyk PT, LeBlanc EV, Kuntz DA, Xue A, Ortiz F, Trilles R, Bengtson S, Kenney TMG, Huang DS, Robbins N, Williams NS, Krysan DJ, Privé GG, Whitesell L, Cowen LE, Brown LE. Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors: Optimization of Whole-Cell Anticryptococcal Activity and Insights into the Structural Origins of Cryptococcal Selectivity. J Med Chem. 2021 Jan 28;64(2):1139-1169. PMCID: PMC8493596..
  3. Liu Y, Gao GF, Minna JD, Williams NS, Westover KD. Loss of wild type KRAS in KRASMUT lung adenocarcinoma is associated with cancer mortality and confers sensitivity to FASN inhibitors. Lung Cancer. 2021 Jan 2; 153: 73-80.   PMCID: PMC7897317.
  4. Shin MK, Vázquez-Rosa E, Koh Y, Dhar M, Chaubey K, Cintrón-Pérez CJ, Barker S, Miller E, Franke K, Noterman MF, Seth D, Allen RS, Motz CT, Rao SR, Skelton LA, Pardue MT, Fliesler SJ, Wang C, Tracy TE, Gan L, Liebl DJ, Savarraj JPJ, Torres GL, Ahnstedt H, McCullough LD, Kitagawa RS, Choi HA, Zhang P, Hou Y, Chiang CW, Li L, Ortiz F, Kilgore JA, Williams NS, Whitehair VC, Gefen T, Flanagan ME, Stamler JS, Jain MK, Kraus A, Cheng F, Reynolds JD, Pieper AA. Reducing acetylated tau is neuroprotective in brain injury. Cell. 2021 May 13;184(10):2715-2732. PMCID: PMC8491234.
  5. Manna MS, Tamer YT, Gaszek I, Poulides N, Ahmed A, Wang X, Toprak FCR, Woodard DR, Koh AY, Williams NS, Borek D, Atilgan AR, Hulleman JD, Atilgan C, Tambar U, Toprak E. A trimethoprim derivative impedes antibiotic resistance evolution. Nat Commun. 2021 May 19;12(1):2949. PMCID: PMC8134463.
  6. Schroeder R, Sridharan P, Nguyen L, Loren A, Williams NS, Kettimuthu KP, Cintrón-Pérez CJ, Vázquez-Rosa E, Pieper AA, Stevens HE. Maternal P7C3-A20 Treatment Protects Offspring from Neuropsychiatric Sequelae of Prenatal Stress. Antioxid Redox Signal. 2021 Sep 1;35(7):511-530. PMCID: PMC8388250.
  7. Elias R, Tcheuyap VT, Kaushik AK, Singla N, Gao M, Reig Torras O, Christie A, Mulgaonkar A, Woolford L, Stevens C, Kettimuthu KP, Pavia-Jimenez A, Boroughs LK, Joyce A, Dakanali M, Notgrass H, Margulis V, Cadeddu JA, Pedrosa I, Williams NS, Sun X, DeBerardinis RJ, Öz OK, Zhong H, Seshagiri S, Modrusan Z, Cantarel BL, Kapur P, Brugarolas J. A renal cell carcinoma tumorgraft platform to advance precision medicine. Cell Rep2021 Nov 23;37(8):110055 PMCID: PMC8762721.
  8. Mohapatra J, Tashiro K, Beckner RL, Sierra J, Kilgore JA, Williams NS, Liszczak G. Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling. Elife2021 Dec 7;10doi: 10.7554/eLife.71502.  PMCID: PMC8683085.
  9. Dogan AB, Rohner NA, Smith JNP, Kilgore JA, Williams NS, Markowitz SD, von Recum HA, Desai AB. Polymer Microparticles Prolong Delivery of the 15-PGDH Inhibitor SW033291. Pharmaceutics2021 Dec 30;14(1)doi: 10.3390/pharmaceutics14010085. PMCID: PMC8779392.