Publications Archive for Bret M. Evers, M.D., Ph.D.
Yu H, Khanshour AM, Ushiki A, Otomo N, Koike Y, Einarsdottir E, Fan Y, Antines L, Kidane YH, Cormelia R, Sheng R, Zhang Y, Pei J, Grishin NV, Evers BM, Yin Cheung JP, Herring JA, Terao C, Song YQ, Gurnett CA, Gerhem P, Ikegawa S, Rios JJ, Ahituv N, Wise CA. "Association of an estrogen-sensitive PAX1-Col11a1-Mmp3 signaling axis with adolescent idiotpathic scoliosis." bioRxiv 2023 May 27: 2023.05.26.542293.
Iyengar P, Ghandi AY, Granados J, Guo T, Gupta A, Yu J, Llano EM, Zhang F, Gao A, Kandathil A, Williams D, Gao B, Girard L, Malladi VS, Shelton JM, Evers BM, Hannan R, Ahn C, Minna JD, Infante RE. "Tumor loss-of-function mutations in STK11/LKB1 induce cachexia." JCI Insight. 2023 Apr 24S1365-182X(23)00130-2.
Choi Y, Lichterman JN, Coughlin LA, Poulides N, Li W, Del Valle P, Palmer SN, Gan S, Kim J, Zhan X, Gao Y, Evers BM, Hooper LV, Pasare C, Koh AY. "Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity." Sci Immunol. 2023 Mar 10;8(81):eabo2003.
Mar KB, Van Dyke MC, Lopez AH, Eitson JL, Fan W, Hanners NW, Evers BM, Shelton JM, Schoggins JW. "LY6E protects mice from pathogenic effects of murine coronavirus and SARS-CoV-2." bioRxiv 2023 Jan 26:2023.01.25.525551.
Bhattacharyya S, Kollipara RK, Orguera-Tornakian G, Goetsch S, Zhang M, Perry C, Li B, Shelton JM, Bhakta M, Duan J, Xie Y, Xiao G, Evers BM, Hon GC, Kittler R, Munshi NV. "Global chromatin landscapes identify candidate noncoding modifiers of cardiac rhythm." J Clin Invest. 2022 Feb 1;133(3):e153635.
Dobariya A, El Ahmadieh TY, Good LB, Hernandez-Reynosa AG, Jakamsetti V, Brown R, Dunbar M, DIng K, Luna J, Kallem RR, Putnam WC, Shelton JM, Evers BM, Azami A, Geramifard N, Cogan SF, Mickey B, Pascual JM. "Recording of pig neuronal activity in the comparative context of the awake human brain." Sci Rep. 2022 Sep 15;12(1):15503-15517.
Cheng N, Li G, Kanchwala M, Evers BM, Xing C, Yu H. "STAG2 promotes the myelination transcriptional program in oligodendrocytes." Elife. 2022 Aug 12;11:e77848.
Casey AK, Gray HF, Chimalapati S, Hernandez G, Moehlman AT, Stewart N, Fields HA, Gulen B, Servage KA, Stefanius K, Blevins A, Evers BM, Kramer H, Orth K. "Fic-mediated AMPylation tempers the unfolded protein response during physiological stress." Proc Natl Acad Sci USA. 2022 Aug 9; 119(32):e2208317119.
Sivakumar S, Qi S, Cheng N, Sathe AA, Kanchwala M, Kumar A, Evers BM, Xing C, Yu H. "TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling." Cell Rep. 2022 Feb 15;38(7):110395.
Beaulieu R, McDonnell E, Scofield-Kaplan SM, Evers BM, Hogan RN, Mancini R. "Conjunctival changes following Muller's muscle conjunctival resection." Int Ophthalmol. 2022 Jan.
Wiseman D, Hanzlik JA, Richardson JA, Shelton JM, Evers BM, Diamond MP, Brown R, Mazzucco DC. "Development of a Chronic Canine Ovariohysterectomy Model to Evaluate Vaginal Cuff Healing Using Two Closure Systems." Surg Innov. 2022 April 18;29(2):183-194.
Mueller AJ, Scofield-Kaplan SM, Evers BM, Carr BC, Mancini R, Hogan RN. "Idiopathic Optic Perineuritis Masquerading as Recurrent Optic Neuritis." J Neuroophthalmol. 2022 Mar 1;42(1):e302-e305.
Chkheidze R, Raisanen J, Gagan J, Richardson TE, Pinho MC, Raj K, Achilleos M, Slepicka C, White CL, Evers BM, Patel TR, Malter JS, Hatanpaa KJ. "Alterations in the RB Pathway With Inactivation of RB1 Characterize Glioblastomas With a Primitive Neuronal Component." J Neuropatho Exp Neurol. 2021 Dec 29;80(12): 1092-1098.
Pohlkamp T, Xian X, Wong CH, Durakoglugil MS, Werthmann GC, Saido TC, Evers BM, White CL 3rd, Connor J, Hammer RE, Herz J. "NHE6-depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load." Elife. 2021 Oct 7.
Ferdous A, Singh S, Luo Y, Abedin MJ, Jiang N, Perry CE, Evers BM, Gillette TG, Kyba M, Trojanowska M, Hill JA. "Fli1 Promotes Vascular Morphogenesis by Regulating Endothelial Potential of Multipotent Myogenic Progenitors." Circ Res. 2021 Oct 29;129(10):949-964.
Fan W, Mar KB, Sari L, Gaszek IK, Cheng Q, Evers BM, Shelton JM, Wight-Carter M, Siegwart DL, Lin MM, Schoggins JW. "TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity." Cell. 2021 Jun 24;184(13):3410-3425.
Carter P, Schnell U, Chaney C, Tong B, Pan X, Ye J, Mernaugh G, Cotton JL, Margulis V, Mao J, Zent R, Evers BM, Kapur P, Carroll TJ. "Deletion of Lats1/2 in adult kidney epithelia leads to renal cell carcinoma." J Clin Invest. 2021 Jun 1;131(11):e144108.
Guo T, Gupta A, Yu J, Granados JZ, Gandhi AY, Evers BM, Iyengar P, Infante RE. "LIFR-a-dependent adipocyte signaling in obesity limits adipose expansion contributing to fatty liver disease." iScience. 2021 Feb 24;24(3):102227.
Ramirez-Martinez A, Zhang Y, Chen K, Kim J, Cenik BK, McAnally JR, Cai C, Shelton JM, Huang J, Brennan A, Evers BM, Mammen PPA, Xu L, Bassel-Duby R, Liu N, Olson EN. "The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization." Nat Commun. 2021 Jan 29;12(1):690.
Wang, X., Wilhelm, J., Li, W., Li, S., Wang, Z., Hunag, G., Wang, J., Tang, H., Khorsandi, S., Sun, Z., Evers, B., Gao, J. "Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window." Nat Commun. 2020 Nov 17;11(1):5828.
Chown, E.E., Wang, P., Zhao, X., Crowder, J.J., Strober, J.W., Sullivan, M.A., Xue, Y., Bennett, C.S., Perri, A.M., Evers, B.M., Roach, P/J., Depaoli-Roach, A.A., Akman, H.O., Pederson, B.A., Minassian, B.A. "GYS1 or PPP1R3C deficiency rescues murine adult poilyglucosan body disease." Ann Clin Transl Neurol. 2020 Nov;7(11):2186-2198.
Chkheidze, R., Evers, B.M., Cavuoti, D., Merritt, J., Hogan, R.N. "Bilateral Acanthamoeba Panophthalmitis: A rare and unique case." Am J Ophthalmol Case Rep. 2020 Oct 16;20:100970.
Kim, S.Y., Zhang, X., Schiatarella, G.G., Altamirano, F., Ramos, T.A.R., French, K.M., Jiang, N., Szweda, P.A., Evers, B.M., May, H.I., Luo, X., Li, H., Szweda, L.I., Maracaja-Coutinho, V., Lavadero, S., Gillett, T.G., Jill, J.A. "Epigenetic Reader BRD4 (Bromodomain-Containing Protein 4) Governs Nucleus-Encoded Mitochondrial Transcriptome to Regulate Cardiac Function." Circulation. 2020 Dec 15;142(24): 2356-2370.
Suresh, S., Chen, B., Zhu, J., Golden, R.J., Lu, C., Evers, B.M., Novaresi, N., Smith, B., Zhan, X., Schmid, V., Wistuba, I.I., Xiao, G., Xie, Y., Fu, F.X., Minna, J.D., Mendell, J.T., O'Donnell, K.A. "eIF5B dives integrated stress response-dependent translation of PD-L1 in lung cancer." Nat Cancer. 2020 May;1(5):533-545.
Lee, J.C., Evers, B.M., Cavuoti, D., Hogan, R.N., Kooner, K.S. "Polymicrobial infection confined to Ahmed galucoma shunt." Am J Ophthalmol Case Rep. 2020 Jan 16;18:100596.
Jo, Y., Kim, S.S., Garland, K., Fuentes, I., DiCarlo, L.M., Ellis, J.L., Fu, X., Booth, S.L., Evers, B.M., DeBose-Boyd, R.A. "Enhanced ER-associated degradation of HMG CoA reductase causes embryonic lethality associated with Ubiad1 deficiency." Elife. 2020 Mar 2;9:e54841.
Misawa, T., SoRelle, J.A., Choi, J.H., Yue, T., Wang, K.W., McAlpine, W., Wang, J., Liu, A., Tabeta, K., Turer, E.E., Evers, B., Nair-Gill, E., Poddar, S., Su, L., Ou, F., Yu, L., Russell, J., Ludwig, S., Zhan, X., Hidebrand, S., Li, X., Tang, M., Murray, A.R., Moresco, E.M.Y., Beutler, B. "Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation." Sci Immunol. 2020 Jan 24;5(43): eaaz0085.
Gao, Y., Deason, K., Jain, A., Irizarry-Caro, R.A., Dozmorov, I., Coughlin, L.A., Rauch, I., Evers, B.M., Koh, A.Y., Wakeland, E.K., Pasare, C. "Transcriptional profiling identifies caspase-1 as a T cell-intrinsic regulator of Th17 differentiation." J Exp Med. 2020 Apr6; 217(4): e20190476.
Scofield-Kaplan, S.M., Patel, S.Y., Mueller, A., Ford, W.C., Evers, B., Hogan, R.N., Mancini, R. "Foreign-Body Granulomata Caused by Injected Pigment Filler Masquerading as Cutaneous Sarcoidosis." Ophthalmic Plast Reconstr Surg. 2019 May/Jun;35(3):e82-e84.
Turer, E.E., San Miguel, M., Wang K.W., McAlpine, W., Ou, F., Li, X., Tang, M., Zang, Z., Wang, J., Hayse, B., Evers, B., Zhan, X., Russell, J., Beutler, B. "A viable hypomorphic Arnt2 mutation causes hyperphagic obesity, diabetes, and hepatic steatosis." Dis Model Mech. 2018 Dec 18;11(12).
Scofield-Kaplan, S.M., Sobti, D., Evers, B., Hogan, R.N., Mancini, R. "Unusual Location for a Periorbital Dermoid Cyst." Ophthalmic Plast Reconstr Surg. 2018 Nov/Dec; 34(6):e208-e209.
Zhou, X., Padanad, M.S., Evers, B., Smith, B., Novaresi, N., Suresh, S., Richardson, J.A., Stein, E., Zhu, J., Hammer, R.E., O'Donnell, K.A. "Modulation of Mutant Kras120D-Driven Lung Tumorigenesis In Vivo By Gain or Loss of PCDH7 Function." Mol Cancer Res. 2019 Feb;17(2): 594-603.
Wajda, B.N., Mancini, R., Evers, B., Nick Hogan, R. "A rare case of atypical pleomorphic adenoma arising from periocular ectopic lacrimal gland." Int Ophthalmol. 2018 Jun 23.
Pottier, C., Zhou, X., Perkerson, R.B. 3rd, Baker, M., Jenkins, G.D., Serie, D.J., Ghidoni, R., Benussi, L., Binetti, G., López de Munain, A., Zulaica, M., Moreno, F., Le Ber, I., Pasquier, F., Hannequin, D., Sánchez-Valle, R., Antonell, A., Lladó, A., Parsons, T.M., Finch, N.A., Finger, E.C., Lippa, C.F., Huey, E.D., Neumann, M., Heutink, P., Synofzik, M., Wilke, C., Rissman, R.A., Slawek, J., Sitek, E., Johannsen, P., Nielsen, J.E., Ren, Y., van Blitterswijk, M., DeJesus-Hernandez, M., Christopher, E., Murray, M.E., Bieniek, K.F., Evers, B.M., Ferrari, C., Rollinson, S., Richardson, A., Scarpini, E., Fumagalli, G.G., Padovani, A., Hardy, J., Momeni, P., Ferrari, R., Frangipane, F., Maletta, R., Anfossi, M., Gallo, M., Petrucelli, L., Suh, E., Lopez, O.L., Wong, T.H., van Rooij, J.G.J., Seelaar, H., Mead, S., Caselli, R.J., Reiman, E.M., Noel, Sabbagh, M., Kjolby, M., Nykjaer, A., Karydas, A.M., Boxer, A.L., Grinberg, L.T., Grafman, J., Spina, S., Oblak, A., Mesulam, M.M., Weintraub, S., Geula, C., Hodges, J.R., Piguet, O., Brooks, W.S., Irwin, D.J., Trojanowski, J.Q., Lee, E.B., Josephs, K.A., Parisi, J.E., Ertekin-Taner, N., Knopman, D.S., Nacmias, B., Piaceri, I., Bagnoli, S., Sorbi, S., Gearing, M., Glass, J., Beach, T.G., Black, S.E., Masellis, M., Rogaeva, E., Vonsattel, J.P., Honig, L.S., Kofler, J., Bruni, A.C., Snowden, J., Mann, D., Pickering-Brown, S., Diehl-Schmid, J., Winkelmann, J., Galimberti, D., Graff, C., Öijerstedt, L., Troakes, C., Al-Sarraj, S., Cruchaga, C., Cairns, N.J., Rohrer, J.D., Halliday, G.M., Kwok, J.B., van Swieten, J.C., White, C.L. 3rd, Ghetti, B., Murell, J.R., Mackenzie, I.R.A., Hsiung, G.R., Borroni, B., Rossi, G., Tagliavini, F., Wszolek, Z.K., Petersen, R.C., Bigio, E.H., Grossman, M., Van Deerlin, V.M., Seeley, W.W., Miller, B.L., Graff-Radford, N.R., Boeve, B.F., Dickson, D.W., Biernacka, J.M., Rademakers, R. "Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study." Lancet Neurol. 2018 Jun;17(6):548-558.
Cheng, B. Chatzinoff, Y., Szczepanski, D. Bing, C., Shaikh, S., Wyman, O., Perry, C.E., Richardson J.A., Burns, D.K., Evers, B.M., Greenberg, D.E., Chopra, R. "Remote acoustic sensing as a safety mechanism during exposure of metal implants to alternating magnetic fields." PLoS One. 2018 May 10;13(5).
Evers, B.M., Rodriguez-Navas, C., Tesla, R.J., Prange-Kiel, J., Wasser, C.R., Yoo, K.S., McDonald, J., Cenik, B., Ravenscroft, T.A., Plattner, F., Rademakers, R., Yu, G., White III, C.L., and Herz, J. "Lipidomic and transcriptomic basis of lysosomal dysfunction in progranulin deficiency." Cell Rep. 2017 Sep;20(11):2565-2574.
Evers, B., Danielsen, T., and Kumar, M. "Mass effect and edema." In Neuropathologic and Neuroradiologic Correlations: A differential diagnostic text and atlas. M. Godken and M. Kumar (Eds.) Cambridge University Press, Cambridge, UK. 2017.
Evers, B.M., Farooqi, M.S., Shelton, J.M., Richardson, J.A., Goldstein, J.L., Brown, M.S., Liang, G. "Hair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatin." J Invest Dermatol. 2010 May;130(5):1237-48.
Engelking, L.J., Evers, B.M., Richardson, J.A., Goldstein, J.L., Brown, M.S., Liang, G. "Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin." J Clin Invest. 2006 Sep;116(9):2356-65.
Engelking, L.J., Liang, G., Hammer, R.E., Takaishi, K., Kuriyama, H., Evers, B.M., Li, W.P., Horton, J.D., Goldstein, J.L., Brown, M.S. "Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins." J Clin Invest. 2005 Sep;115(9):2489-98.
Dindot, S.V., Kent, K.C., Evers, B., Loskutoff, N., Womack, J., Piedrahita, J.A. "Conservation of genomic imprinting at the XIST, IGF2, and GTL2 loci in the bovine." Mamm Genome. 2004 Dec;15(12):966-74.