Skip to Main
CEMF banner 1 desktop

CEMF Operations

The Titan™ Krios microscope can provide 3D images of biological molecules with up to atomic resolution.

CEMF banner 2 desktop
 

Single-Particle Cryo-EM

Provides 3D reconstructions of macromolecules and their assemblies. Shown: ribosomes.

CEMF banner 3 desktop- tomography
 

Cryo-Tomography

A new window into the 3D ultra-structure of cells, organelles, and macromolecular complexes. Shown: structure of a cilium.

CEMF banner 4 desktop
 

Cryo-FIB Milling

Development of this “nano-sandblaster” will facilitate cryo-tomography deep inside cells.

This state-of-the-art facility provides access to the 2017 Nobel-prize winning technology of atomic-resolution single particle cryo-electron microcopy (cryo-EM) and cellular cryo-electron tomography to tackle unanswered questions in structural cell biology and to provide a new understanding of the molecular causes of diseases.

Equipment Status

North Campus (NL1.180D) Titan™ KriosOnline  

 South Campus (L1.240B) Titan™ KriosOffline  

Talos™ Arcticaoffline  

Talos™ Glacios:   Offline  

Getting Started

  1. Review our policies and rates.

  2. Study our resources for first-time Cryo-EM users.

  3. Create an iLab account to schedule equipment.

  4. Refer to our manuals and sample information form.

About Our Funding

CEMF is supported by a grant from the Cancer Prevention & Research Institute of Texas (RP170644).

Location

Mailing Address

Cryo-Electron Microscopy Facility
UT Southwestern Medical Center
6000 Harry Hines Blvd.
Dallas, TX 75390-9039

Core Director

Daniel.Stoddard@UTSouthwestern.edu