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2025 Article Archive

UTSW Physiology Chair, molecular biologist elected to National Academy of Medicine

 

Duojia Pan, Ph.D., Chair and Professor of Physiology at UT Southwestern Medical Center, and Joshua Mendell, M.D., Ph.D., Professor of Molecular Biology, have been elected to the National Academy of Medicine (NAM), one of the highest honors in the fields of health and medicine.

Study examines biological causes of cancer deaths

 

The ultimate cause of death from cancer isn’t metastatic disease, as researchers have long surmised, but an infiltration of tumors into major blood vessels that cause blood clots and multiorgan failure, a one-of-a-kind clinical study led by UT Southwestern Medical Center suggests.

Neurons in brain’s timekeeper might control nighttime hunger

 

Activating specific neurons in a part of the brain that serves as the body’s master circadian pacemaker caused mice to eat significantly more during a time of day when they would normally be at rest, a UT Southwestern Medical Center study shows.

Stressors damage kidneys by mutating mitochondrial DNA

 

Kidney damage that seemingly heals appears to mutate the DNA in the mitochondria of kidney cells, making the organ less resilient to future stressors and reducing its function over time, a study led by UT Southwestern Medical Center researchers shows.

AI can identify stroke types using clinical notes, study shows

 

Using only text from doctors’ notes and radiology reports, an artificial intelligence (AI) program known as GPT-4o reliably identified patients’ types of strokes, UT Southwestern Medical Center researchers found.

Kidney cancer drug shows promise against dangerous calcium imbalance caused by tumors

 

Elevated calcium levels in the blood – a complication of kidney cancers known as hypercalcemia – may be successfully treated with a class of medications called HIF-2 inhibitors developed by UT Southwestern Medical Center, a new study shows. The findings, published in Cancer Discovery by a team at UTSW, could offer hope to patients who develop this condition.

UT Southwestern researcher receives NIH Director’s New Innovator Award

 

David Sanders, Ph.D., Assistant Professor in the Center for Alzheimer’s and Neurodegenerative Diseases and Molecular Biology at UT Southwestern Medical Center, has been awarded $2.4 million over five years from the National Institutes of Health (NIH) to support his research into the role of RNA/protein assemblies in neurodegenerative diseases.

UTSW discovery opens door to novel strategies for hard-to-treat cancers

 

UT Southwestern Medical Center researchers have identified two distinct populations of cells known as antigen-presenting cancer-associated fibroblasts (apCAFs) that appear to support the survival and growth of malignant tumors. Their findings, reported in Cancer Cell, could one day lead to new therapies for notoriously hard-to-treat cancers, including pancreatic cancer and advanced colorectal cancer (CRC) that has spread throughout the abdomen, known as peritoneal metastasis.

UT Southwestern and Children’s Health receive $25 million from the Harry W. Bass, Jr. Foundation for new pediatric campus

 

UT Southwestern Medical Center and Children’s Health announced a $25 million gift from the Harry W. Bass, Jr. Foundation, directed through Southwestern Medical Foundation, in support of their $5 billion transformative joint pediatric campus under construction in Dallas’ Southwestern Medical District across from UTSW’s William P. Clements Jr. University Hospital.

New CEO to lead UTSW’s Clements University Hospital

 

Traci d’Auguste, M.B.A., M.S.H.A., who has more than two decades of leadership experience in academic medicine, is the new Vice President and Chief Executive Officer of UT Southwestern Medical Center’s William P. Clements Jr. University Hospital (CUH), effective today.