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Gene therapy offers hope for giant axonal neuropathy patients

 

A gene therapy developed by researchers at UT Southwestern Medical Center for a rare disease called giant axonal neuropathy (GAN) was well tolerated in pediatric patients and showed clear benefits, a new study reports.

Gut microbiome offers clues to disparities in rectal cancer

 

The composition of the gut microbiomes in a group of rectal cancer patients reveals distinct signatures by race, ethnicity, and age of onset, with white Hispanics showing significant presence of one specific bacteria, UT Southwestern Medical Center researchers report.

Match Day magic: UTSW students earn top residency spots

 

At exactly 11 a.m. Friday, surrounded by family, friends, and mentors, 224 members of UT Southwestern Medical School’s Class of 2024 – who all embarked on their medical education during the height of the COVID-19 pandemic – learned where they will continue their medical training.

Lung cancer treatment shows promise in tumor models

 

A molecule has demonstrated its ability to kill tumor cells and incite an immune response in preclinical models of small cell lung cancer (SCLC), according to UT Southwestern Medical Center researchers.

Simmons Cancer Center awarded nearly $19 million in CPRIT funding

 

Nine scientists and physicians in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center have been awarded nearly $13 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to support research and prevention efforts on a wide range of cancer issues.

How gut bacteria become ‘persisters’ to avoid antibiotics

 

A subpopulation of gut bacteria given a commonly used antibiotic became “persisters” that were able to survive without developing true resistance, UT Southwestern Medical Center scientists discovered.

Gold nanoparticles reverse brain deficits in multiple sclerosis, Parkinson’s

 

Results from phase two clinical trials at UT Southwestern Medical Center showed that a suspension of gold nanocrystals taken daily by patients with multiple sclerosis (MS) and Parkinson’s disease (PD) significantly reversed deficits of metabolites linked to energy activity in the brain and resulted in functional improvements.

Children’s Health and UT Southwestern announce plans for transformative new pediatric campus in Dallas’ Southwestern Medical District

 

Children’s HealthSM and UT Southwestern Medical Center unveiled plans for a new $5 billion pediatric health campus in Dallas’ Southwestern Medical District today. Spanning more than 33 acres, the new pediatric campus offers a patient-centric design that can meet the rapidly increasing need for more pediatric services ranging from the most common to the most complex.

New options at Dallas food pantry boost food security

 

Nutritious meal kits and no-prep meals improved food security and perceived dietary quality among clients of a Dallas food pantry, according to a pilot study led by UT Southwestern Medical Center.

Activating cerebellum shows promise for neurocognitive therapy

 

A study of mutant models of fragile X syndrome (FXS), a genetic disorder related to autism and intellectual disability, shows that activation of the cerebellum mitigates aberrant responses in sensory processing areas of the brain and improves neurodevelopmental behaviors.