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Dallas Heart Study Bibliography (2001–2018)

Published Peer-Reviewed Journal Articles


  • Sadhu M, Jalalizadeh B, Fritz A, Nicholson TF, Garcia R, Lampley S, Rain M, Van Enkevort E, Brown ES (2019). Trust in physicians and regional brain volumes: a population-based study. Prim Care Companion CNS Disord. 21(5):19m02461.
  • Rader F, Franklin SS, Mirocha J, Vongpatanasin W, Haley RW, Victor RG (2019). Superiority of out-of-office blood pressure for predicting hypertensive heart disease in non-hispanic black adults. Hypertension In press.
  • Hackler E 3rd, Lew J, Gore MO, Ayers CR, Atzler D, Khera A, Rohatgi A, Lewis A, Neeland I, Omland T, de Lemos JA (2019). Racial differences in cardiovascular biomarkers in the general population. J Am Heart Assoc. 8(18):e012729.
  • Aagaard P, Sharma S, McNamara DA, Joshi P, Ayers CR, de Lemos JA, Lincoln AE, Baranowski B, Mandsager K, Hill E, Castle L, Gentry J 3rd, Lang R, Dunn RE, Alexander K, Tucker AM, Phelan D (2019). Arrhythmias and adaptations of the cardiac conduction system in former national football league players. J Am Heart Assoc. 8(15):e010401.
  • Papachristou C, Biswas S (2019). Comparison of haplotype-based tests for detecting gene-environment interactions with rare variants. Brief Bioinform. In press.
  • Vora A, de Lemos JA, Ayers C, Grodin JL, Lingvay I (2019). Association of Galectin-3 with Diabetes Mellitus in the Dallas Heart Study. J Clin Endocrinol Metab. In press.
  • Eades MT, Paixao ARM, Mehta A, Ayers CR, Joshi PH, Berry JD, de Lemos JA, Khera A (2019). Characterization and trajectory of coronary artery calcium percentiles: The Dallas Heart Study. JACC Cardiovasc. Imaging In press.
  • Khwaja R, Dessouky R, Heffler MA, Xi Y, Neeland IJ, Chhabra A (2019). Multi-compartment mesenchymal tissue segmentation in pelvic MRI examinations of women: Anthropomorphic and clinical correlations. Eur J Radiol. 112: 37-43.
  • Ferre S, Li X, Adams-Huet B, Maalouf NM, Sakhaee K, Toto RD, Moe OW, Neyra JA (2019). Low serum magnesium is associated with faster decline in kidney function: the Dallas Heart Study experience. J Investig Med. In press.
  • Sadhu M, Nicholson TF, Garcia R, Lampley S, Rain M, Fritz A, Jalalizadeh B, Van Enkevort E, Palka J, Brown ES (2019). Relationship between trust in neighbors and regional brain volumes in a population-based study. Psychiatry Res Neuroimaging 286:11-17.
  • Peri-Okonny P, Baskin KK, Iwamoto G, Mitchell JH, Smith SA, Kim HK, Szweda LI, Bassel-Duby R, Fujikawa T, Castorena CM, Richardson J, Shelton JM, Ayers C, Berry JD, Malladi VS, Hu MC, Moe OW, Scherer PE, Vongpatanasin W (2019). High-phosphate diet induces exercise intolerance and impairs fatty acid metabolism in mice. Circulation 139:1422-1434.
  • McNamara DA, Bennett AJ, Ayers C, de Lemos JA, Berry JD, Link MS (2019). Early repolarization pattern is associated with increased left ventricular mass: insights from Dallas Heart Study. JACC Clin Electrophysiol. 5:395-397.
  • Dongiovanni P, Meroni M, Baselli GA, Mancina RM, Ruscica M, Longo M, Rametta R, Cespiati A, Pelusi S, Ferri N, Ranzani V, Nobili V, Pihlajamaki J, Fracanzani AL, Badiali S, Petta S, Fargion S, Romeo S, Kozlitina J, Valenti L (2019). PCSK7 gene variation bridges atherogenic dyslipidemia with hepatic inflammation in NAFLD patients. J Lipid Res. 60:1144-1153.


  • Vongpatanasin W, Ayers C, Lodhi H, Das SR, Berry JD, Khera A, Victor RG, Lin FC, Viera AJ, Yano Y, de Lemos JA (2018). Diagnostic thresholds for blood pressure measured at home in the context of the 2017 Hypertension Guideline. Hypertension. 72:1312-1319.
  • Daftary S, Van Enkevort E, Kulikova A, Legacy M, Brown ES (2018). Relationship between depressive symptom severity and amygdala volume in a large community-based sample. Psychiatry Res Neuroimaging. 283:77-82.
  • Kaja R, Reyes SM, Rossetti HC, Brown ES (2018). Association between telomere length and cognitive ability in a community-based sample. Neurobiol Aging. 75:51-53.
  • Solow EB, Vongpatanasin W, Skaug B, Karp DR, Ayers C, de Lemos JA (2018). Antinuclear antibodies in the general population: positive association with inflammatory and vascular biomarkers but not traditional cardiovascular risk factors. Clin Exp Rheumatol. 36:1031-1037.
  • Alame AJ, Garg S, Kozlitina J, Ayers C, Peshock RM, Matulevicius SA, Drazner MH (2018). Association of African ancestry with electrocardiographic voltage and concentric left ventricular hypertrophy: The Dallas Heart Study. JAMA Cardiol. In press.
  • Neeland IJ, Singh S, McGuire DK, Vega GL, Roddy T, Reilly DF, Castro-Perez J, Kozlitina J, Scherer PE (2018). Relation of plasma ceramides to visceral adiposity, insulin resistance and the development of type 2 diabetes mellitus: the Dallas Heart Study. Diabetologia. 61:2570-2579.
  • Claudel SE, Adu-Brimpong J, Banks A, Ayers C, Albert MA, Das SR, de Lemos JA, Leonard T, Neeland IJ, Rivers JP, Powell-Wiley TM (2018). Association between neighborhood-level socioeconomic deprivation and incident hypertension: A longitudinal analysis of data from the Dallas Heart Study. Am Heart J. 204:109-118.
  • Akula M, Kulikova A, Khan DA, Brown ES (2018). The relationship between asthma and depression in a community-based sample. J Asthma. 55:1271-1277.
  • Abul-Husn NS, Cheng X, Li AH, Xin Y, Schurmann C, Stevis P, Liu Y, Kozlitina J, Stender S, Wood GC, Stepanchick AN, Still MD, McCarthy S, O’Dushlaine C, Packer JS, Balasubramanian S, Gosalia N, Esopi D, Kim SY, Mukherjee S, Lopez AE, Fuller ED, Penn J, Chu X, Luo JZ, Mirshahi UL, Carey DJ, Still CD, Feldman MD, Small A, Damrauer SM, Rader DJ, Zambrowicz B, Olson W, Murphy AJ, Borecki IB, Shuldiner AR, Reid JG, Overton JD, Yancopoulos GD, Hobbs HH, Cohen JC, Gottesman O, Teslovich TM, Baras A, Mirshahi T, Gromada J, Dewey FE (2018). A protein-truncating HSD17B13 variant and protection from chronic liver disease. N Engl J Med. 378:1096-1106.


  • Stender S, Smagris E, Lauridsen BK, Kofoed KF, Nordestgaard BG, Tybjaerg-Hansen A, Pennacchio LA, Dickel DE, Cohen JC, Hobbs HH (2017). Relationship between genetic variation at PPP1R3B and liver glycogen and triglyceride levels. Hepatology. 67:2182-2195.
  • Dongiovanni P, Stender S, Pietrelli A, Mancina RM, Cespiati A, Petta S, Pelusi S, Pingitore P, Badiali S, Maggioni M, Mannisto V, Grimuado S, Pipitone RM, Pihlajamaki J, Craxi A, Taube M, Carlsson LMS, Fargion S, Romeo S, Kozlitina J, Valenti L (2017). Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver. J Intern Med. 238:356-370.
  • Gentry JL, Carruthers D, Joshi PH, Maroules CD, Ayers CR, de Lemos JA, Aagaard P, Hachamovitch R, Desai MY, Roselli EE, Dunn RE, Alexander K, Lincoln AE, Tucker AM, Phelan DM (2017). Ascending aortic dimensions in former National Football League athletes. Circ Cardiovasc Imaging. 10(11). Pii:e006852. doi:10.1161/CIRCIMAGING.117.006852.
  • Stender S, Kozlitina J, Nordestgaard BG, Tybjaerg-Hansen A, Hobbs HH, Cohen JC (2017). Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci. Nat Genet. 49:842-847.
  • Chakrabarti RS, Ingham SA, Kozlitina J, Gay A, Cohen JC, Radhakrishnan A, Hobbs HH (2017). Variability of cholesterol accessibility in human red blood cells measured using a bacterial cholesterol-binding toxin. eLife 2017;6:e23355.
  • Ferre S, Li X, Adams-Huet B, Maalouf NM, Sakhaee K, Toto RD, Moe OW, Neyra JA (2017). Association of serum magnesium with all-cause mortality in patients with and without chronic kidney disease in the Dallas Heart Study.  Nephrol Dial Transplant. 33:1389-1396.
  • Harrington JL, Ayers C, Berry JD, Omland T, Pandey A, Seliger SL, Ballantyne CM, Kulinski J,  deFilippi CR, de Lemos JA (2017). Sedentary behavior and subclinical cardiac injury: results from the Dallas Heart Study. Circulation 136: 1451-1453.
  • Ren HY, Khera A, de Lemos JA, Ayers CR, Rohatgi A (2017). Soluble endothelial cell-selective adhesion molecule and incident cardiovascular events in a multiethnic population. Am Heart J 191:55-61.
  • Cenik B, Cenik C, Synder MP, Brown ES (2017). Plasma sterols and depressive symptom severity in a population-based cohort. PLoS One 12:e0184382.
  • Pandey A, Park B, Martens S, Ayers C, Neeland IJ, Haykowsky MJ, Nelson MD, Sarma S, Berry JD (2017). Relationship of cardiorespiratory fitness and adiposity with left ventricular strain in middle-age adults (from the Dallas Heart Study). Am J Cardiol 120: 1405-1409.
  • Hlis RD, McIntyre RS, Maalouf NM, Van Enkevort E, Brown ES (2017). Association between bone mineral density and depressive symptoms in a population-based sample. J Clin Psychiatry. 79. pii 16m11276.
  • Garg S, de Lemos JA, Matulevicius SA, Ayers C, Pandey A, Neeland IJ, Berry JD, McColl R, Maroules C, Peshock RM, Drazner MH (2017). Association of concentric left ventricular hypertrophy with subsequent change in left ventricular end-diastolic volume: the Dallas Heart Study. Circ Heart Fail. 10(8).
  • Paixao ARM, Neeland IJ, Ayers CR, Xing F, Berry JD, de Lemos JA, Abbara S, Peshock RM, Khera A (2017). Defining coronary artery calcium concordance and repeatability- implications for development and change: The Dallas Heart Study. J Cardiovasc Comput Tomogr. 11:347-353.
  • Wilner B, Garg S, Ayers CR, Maroules CD, McColl R, Matulevicius SA, de Lemos JA, Drazner MH, Peshock R, Neeland IJ (2017). Dynamic relation of changes in weight and indices of fat distribution with cardiac structure and function: the Dallas Heart Study. J Am Heart Assoc 6(7).
  • Khine HW, Teiber JF, Haley RW, Khera A, Ayers CR, Rohatgi A (2017). Association of the serum myeloperoxidase/high-density lipoprotein particle ratio and incident cardiovascular events in a multi-ethnic population: Observations from the Dallas Heart Study. Atherosclerosis 263:156-162.
  • Yano Y, Neeland IJ, Ayers C, Peshock R, Berry JD, Lloyd-Jones DM, Greenland P, Mitchell GF, Vongpatanasin W (2017). Hemodynamic and mechanical properties of the proximal aorta in young and middle-aged adults with isolated systolic hypertension: the Dallas Heart Study. Hypertension 70:158-165.
  • Mirfakhraee S, Ayers CR, McGuire DK, Maalouf NM (2017). Longitudinal changes in serum 250 hydroxyvitamin D in the Dallas Heart Study. Clin Endocrinol. 87:242-248.
  • Leonard T, Ayers C, Das S, Neeland IJ, Powell-Wiley T (2017). Do neighborhoods matter differently for movers and non-movers? Analysis of weight gain in the longitudinal Dallas heart study. Health Place. 44:52-60.
  • Gupta A, Pandey A, Ayers C, Beg MS, Lakoski SG, Vega GL, Grundy SM, Johnson DH, Neeland IJ (2017). An analysis of individual body fat depots and risk of developing cancer: insights from the Dallas Heart Study. Mayo Clin Proc. 92: 536-543.
  • Wignall ND, Deschner M, Evans HM, Brown ES (2017). Relationship between current depressive symptoms and telomere length in a large, multiethnic sample. J Clin Psychiatry. 78:1331-1336.
  • de Lemos JA, Ayers CR, Levine BD, deFilippi CR, Wang TJ, Hundley WG, Berry JD, Seliger SL, McGuire DK, Ouyang P, Drazner MH, Budoff MJ, Greenland P, Ballantyne CM, Khera A (2017). A multimodality strategy for cardiovascular risk assessment performance in two population-based cohorts. Circulation. 135:2119-2132.
  • Sugasawa S, Noma H, Otani T, Nishino J, Matsui S (2017). An efficient and flexible test for rare variant effects. Eur J Hum Genet.  25:725-757.
  • Prasad A, Clopton P, Ayers C, Khera A, de Lemos JA, Witztum JL, Tsimikas S (2017). Relationship of autoantibodies to MDA-LDL and ApoB-Immune complexes to sex, ethnicity, subclinical atherosclerosis, and cardiovascular events. Arterioscler Thromb Vasc Biol. 37:1213-1221.
  • Lew J, Sanghavi M, Ayers CR, McGuire DK, Omland T, Atzler D, Gore MO, Neeland I, Berry JD, Khera A, Rohatgi A, de Lemos JA (2017). Sex-based differences in cardiometabolic biomarkers. Circulation. 135: 544-555.
  • Oliver W, Matthews G, Ayers CR, Garg S, Gupta S, Neeland IJ, Drazner MH, Berry JD, Matulevicius S, de Lemos JA (2017). Factors associated with left atrial remodeling in the general population. Circ Cardiovasc Imaging. 10(2). Pii:e005047.


  • Peri-Okonny PA, Ayers C, Maalouf N, Das SR, de Lemos JA, Berry JD, Turer AT, Neeland IJ, Scherer PE, Vongpatanasin W (2016). Adiponectin predicts incident hypertension independent of body fat distribution: observations from the Dallas Heart Study. Diabetes Metab Res. 33(2):10.1002/dmrr.2840.
  • Yano Y, Vongpatanasin W, Ayers C, Turer A, Chandra A, Carnethon MR, Greenland P, de Lemos JA, Neeland IJ (2016). Regional fat distribution and blood pressure level and variability: the Dallas Heart Study. Hypertension. 68: 576-83. 
  • Neeland IJ, Grundy SM, Li X, Adams-Huet B, Vega GL (2016). Comparison of visceral fat mass measurement by dual-X-ray absorptiometry and magnetic resonance imaging in a multiethnic cohort: the Dallas Heart Study. Nutr Diabetes. 6:e221. 
  • Zhu D, Hu YQ, Lin S (2016). Block-based association tests for rare variants using Kullback-Leibler divergence. J Hum Genet. In press.
  • Brownell NK, Khera A, de Lemos JA, Ayers CR, Rohatgi A (2016). Association between peptidoglycan recognition protein-1 and incident atherosclerotic cardiovascular disease events: the Dallas Heart Study. J Am Coll Cardiol. 67: 2310-2.
  • Carlson SM, Kim J, Khan DA, King K, Lucarelli RT, McColl R, Peshock R, Brown ES (2016). Hippocampal volume in patients with asthma: results from the Dallas Heart Study. J Asthma. 54:9-16.
  • Mody P, Joshi PH, Khera A, Ayers CR, Rohatgi A (2016). Beyond coronary calcification, family history, and c-reactive protein: cholesterol efflux capacity and cardiovascular risk prediction. J Am Coll Cardiol. 67:2480-7. 
  • Kozlitina J, Zhou H, Brown PN, Rohm RJ, Pan Y, Ayanoglu G, Du X, Rimmer E, Reilly DF, Roddy TP, Cully DF, Vogt TF, Blom D, Hoek M (2016). Plasma levels of risk-variant APOL1 do not associate with renal disease in a population-based cohort. J Am Soc Nephrol. 27:3204-3219.
  • Vsevolozhskaya OA, Zaykin DV, Barondess DA, Tong X, Jadhav S, Lu Q (2016). Uncovering local trends in genetic effects of multiple phenotypes via functional linear models. Genet Epidemiol. 40:210-21.
  • Witberg G, Ayers CR, Turer AT, Lev E, Kornowski R, de Lemos J, Neeland IJ (2016). Relation of adiponectin to all-cause mortality, cardiovascular mortality, and major adverse cardiovascular events (from the Dallas Heart Study). Am J Cardiol. 117:574-9.
  • Mancina RM, Dongiovanni P, Petta S, Pingitore P, Meroni M, Rametta R, Boren J, Montalcini T, Pujia A, Wilkund O, Hindy G, Spagnuolo R, Motta BM, Pipitone RM, Craxi A, Fargion S, Nobili V, Kakela P, Karja V, Mannisto V, Pihlajamaki J, Reilly DF, Castro-Perez J, Kozlitina J, Valenti L, Romeo S (2016). The MBOAT7-TMC4 variant rs641738 increases risk of nonalcoholic fatty liver disease in individuals of European descent. Gastroenterology. 150: 1219-1230.
  • Wen Y, He Z, Li M, Lu Q (2016). Risk prediction modeling of sequencing data using a forward random field method. Sci Rep. 6:21120. doi: 10.1038/srep21120.
  • Pandey A, Park BD, Ayers C, Das SR, Lakoski S, Matulevicius S, de Lemos JA, Berry JD (2016). Determinants of Racial/Ethnic Differences in Cardiorespiratory fitness (from the Dallas Heart Study). Am J Cardiol. 118: 499-503.
  • Gupta A, Herman Y, Ayers C, Beg MS, Lakoski SG, Abdullah SM, Johnson DH, Neeland IJ (2016). Plasma leptin levels and risk of incident cancer: results from the Dallas Heart Study. PLoS One. 11: e0162845.
  • Risso DS, Kozlitina J, Sainz E, Gutierrez J, Wooding S, Getachew B, Luiselli D, Berg CJ, Drayna D (2016). Genetic variation in the TAS2R38 bitter taste receptor and smoking behaviors. PLoS One. 11:e0164157.
  • Li H, Chen J (2016). Efficient unified rare variant association test by modeling the population genetic distribution in case-control studies. Genet Epidemiol. 40: 579-590.
  • Peri-Okonny P, Ayers C, Maalou N, Das S, de Lemos J, Berry J, Turer A, Neeland I, Scherer P, Vongpatanasin W (2016). YIA 02-04 relationship between leptin and incident hypertension: observations from the Dallas Heart Study. J Hypertens. 2016 Sep;34 Suppl 1 - ISH 2016 Abstract Book:e203.
  • Lee SR, Prasad A, Choi YS, Xing C, Clopton P, Witztum JL, Tsimikas S (2016). The LPA gene, ethnicity, and cardiovascular events. Circulation. 135:251-263.
  • Goel A, Maroules CD, Mitchell GF, Peshock R, Ayers C, McColl R, Vongpatanasin W, King KS (2016). Ethnic difference in proximal aortic stiffness: an observation from the Dallas Heart Study. JACC Cardiovasc Imaging. 10:54-61.
  • Kavousi M, Desai CS, Ayers C, Blumenthal RS, Budoff MJ, Mahabadi AA, Ikram MA, van der Lugt A, Hofman A, Erbel R, Khera A, Geisel MH, Jockel KH, Lehmann N, Hoffmann U, O’Donnell CJ, Massaro JM, Liu K, Mohlenkamp S, Ning H, Franco OH, Greenland P (2016). Prevalence and prognostic implications of coronary artery calcification in low-risk women: a meta analysis. JAMA. 316: 2126-2134.
  • Mani P, Ren HY, Neeland IJ, McGuire DK, Ayers CR, Khera A, Rohatgi A (2016). The association between HDL particle concentration and incident metabolic syndrome in the multi-ethnic Dallas Heart Study. Diabetes Metab Syndr. 11 Suppl 1:S175-S179.

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  • McClelland RL, Jorgensen NW, Budoff M, Blaha MJ, Post WS, Kronmal RA, Bild DE, Shea S, Liu K, Watson KE, Folsom AR, Khera A, Ayercs C, Mahabadi AA, Lehmann N, Jockel KH, Moebus S, Carr JJ, Erbel R, Burke GL (2015). 10-Year coronary heart disease risk prediction using coronary artery calcium and traditional risk factors: derivation in the MESA (Multi-Ethnic Study of Atherosclerosis) with Validation in the HNR (Heinz Nixdorf Recall) Study and the DHS (Dallas Heart Study). J Am Coll Cardiol 66:1643-53.
  • Kim S, Lee K, Sun H (2015). Statistical selection strategy for risk and protective rare variants associated with complex traits. J Comput Biol. 22:1034-43.
  • Paixao AR, Ayers CR, El Sabbagh A, Sanghavi M, Berry JD, Rohatgi A, Kumbhani DJ, McGuire DK, Das SR, de Lemos JA, Khera A (2015). Coronary artery calcium improves risk classification in younger populations. JACC Cardiovasc Imaging. 11:1285-93.
  • Velasco A, Ayers C, Das SR, de Lemos JA, Khera A, Victor RG, Kaplan NM, Vongpatanasin W (2015). Target organ complications and prognostic significance of alerting reaction: analysis from the Dallas Heart Study. J Hypertens. 34:226-34.
  • Parikh RH, Seliger SL, de Lemos J, Nambi V, Christenson R, Ayers C, Sun W, Gottdiener JS, Kuller LH, Ballantyne C, deFilippi CR (2015). Prognostic significance of high-sensitivity cardiac troponin T concentrations between the limit of blank and limit of detection in community-dwelling adults: a meta-analysis. Clin Chem 61:1524-31.
  • Tientcheu D, Ayers C, Das SR, McGuire DK, de Lemos JA, Khera A, Kaplan N, Victor R, Vongpatanasin W (2015). Target organ complications and cardiovascular events associated with masked hypertension and white-coat hypertension: analysis from the Dallas Heart Study. J Am Coll Cardiol.66:2159-69.
  • Skeldon AM, Morizot A, Douglas T, Santoro N, Kursawe R, Kozlitina J, Caprio S, Mehal WZ, Saleh M (2015). Caspase-12 but not caspase-11 inhibits obesity and insulin resistance. J Immunol. 196:437-47.
  • Chang Ay, Oshiro J, Ayers C, Auchus RJ (2015). Influence of race/ethnicity on cardiovascular risk factors in polycystic ovary syndrome, the Dallas Heart Study. Clin Endocrinol (Oxf). 85: 92-9.
  • Garg S, de Lemos JA, Ayers C, Khouri MG, Pandey A, Berry JD, Peshock RM, Drazner MH (2015). Association of a 4-tiered classification of LV hypertrophy with adverse CV outcomes in the general population. JACC Cardiovasc Imaging. 8: 1034-41.
  • Datta As, Biswas S (2015). Comparison of haplotype-based statistical tests for disease association with rare and common variants. Brief Bioinform. 17:657-71.
  • Gupta DK, de Lemos JA, Ayers CR, Berry JD, Wang TJ (2015). Racial differences in natriuretic peptide levels: The Dallas Heart Study. JACC Heart Fail 3:513-519.
  • Jacobson DR, Alexander AA, Tagoe C, Buxbaum JN (2015). Prevalence of the amyloidogenic transthyretin (TTR) V122l allele in 14333 African-Americans. Amyloid. 22:171-4.
  • Beg MS, Saleem S, Turer A, Ayers C, de Lemos JA, Khera A, Scherer PE, Lakoski SG (2015). A prospective analysis of plasma adiponectin and risk of incident cancer: The Dallas Heart Study. J Natl Compr Canc Netw. 13:873-8.
  • Gupta M, King KS, Srinivasa R, Weiner MF, Hulsey K, Ayers CR, Whittemore A, McColl RW, Rossetti HC, Peshock RM (2015). Association of 3.0-T brain magnetic resonance imaging biomarkers with cognitive function in the Dallas Heart Study. 72:170-5. JAMA Neurol. 
  • Chandra A, Neeland IJ, Das SR, Khera A, Turer AT, Ayers CR, McGuire DK, Rohatgi A (2015). Relation of black race between high-density lipoprotein cholesterol content, high-density lipoprotein particles and coronary events (from the Dallas Heart Study). Am J Cardiol. 115:890-4.
  • Sanghavi M, Kulinski J, Ayers CR, Nelson D, Stewart R, Parikh N, de Lemos JA, Khera A (2015). Association between number of live births and markers of subclinical atherosclerosis: The Dallas Heart Study. Eur J Prev Cardiol. 23:391-9.
  • Warren MW, Weiner MF, Rossetti HC, McColl R, Peshock R, King KS (2015). Cognitive impact of lacunar infarcts and white matter hyperintensity volume.  Dement Geriatr Cogn Dis Extra 5:170-5.
  • Powell-Wiley TM, Cooper-McCann R, Ayers C, Berrigan D, Lian M, McClurkin M, Ballard-Barbash R, Das SR, Hoehner CM, Leonard T (2015). Change in neighborhood socioeconomic status and weight gain: Dallas Heart Study. Am J Prev Med. 49: 72-9.
  • Rossetti HC, Weiner M, Hynan LS, Cullum CM, Khera A, Lacritz LH (2015). Subclinical atherosclerosis and subsequent cognitive function. Atherosclerosis. 241:36-41.
  • Turkmen AS, Yan Z, Hu YQ, Lin S (2015). Kullback-Leibler distance methods for detecting disease association with rare variants from sequencing data. Ann Hum Genet. 79:199-208.
  • Byrd JB, Auchus RJ, White PC (2015). Aldosterone synthase promoter polymorphism and cardiovascular phenotypes in a large, multiethnic population-based study. J Investig Med. 63:862-6.
  • Srinivasa RN, Rossetti HC, Gupta MK, Rosenberg RN, Weiner MF, Peshock RM, McColl RW, Hynan LS, Lucarelli RT, King KS (2015). Cardiovascular risk factors associated with smaller brain volumes in regions identified as early predictors of cognitive decline. Radiology 28:142488.

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  • Stiles AR, Kozlitina J, Thompson BM, McDonald JG, King KS, Russell DW (2014). Genetic, anatomic, and clinical determinants of human serum sterol and vitamin D levels. USA 111:E4006-14. P Natl Acad Sci
  • Vsevolozhskaya OA, Zaykin DV, Greenwood MC, Wei C, Lu Q (2014). Functional analysis of variance for association studies. PLoS One 9:e105074.
  • Wei C, Li M, He Z, Vsevolozhskaya O, Schaid DJ, Lu Q (2014). A weighted u-statistic for genetic association analyses of sequencing data. Genet Epidemiol. 38:699-708.
  • King KS, Kozlitina J, Rosenberg RN, Peshock RM, McColl RW, Garcia CK (2014). Effect of leukocyte telomere length on total and regional brain volumes in a large population-based cohort. JAMA Neurol. 71:1247-54.
  • Atzler D, Gore MO, Ayers CR, Choe CU, Boger RH, de Lemos JA, McGuire DK, Schwedhelm E. (2014). Homoarginine and cardiovascular outcome in the population-based Dallas Heart Study. Arterioscler Thromb Vasc Biol. 34:2501-7.
  • Chandra A, Neeland IJ, Berry JD, Ayers CR, Rohatgi A, Das SR, Khera A, McGuire DK, de Lemos JA, Turer AT (2014). The relationship of body mass and fat distribution with incident hypertension: Observations from the Dallas Heart Study. J Am Coll Cardiol. 64:997-1002.
  • Xing FY, Neeland IJ, Gore MO, Ayers CR, Paixao AR, Turer AT, Berry JD, Khera A, de Lemos JA, McGuire DK (2014). Association of prediabetes by fasting glucose and/or haemoglobin A1c levels with subclinical atherosclerosis and impaired renal function: Observations from the Dallas Heart Study. Diabetes Vasc Dis Re. 11:11-8.
  • Li M, He Z, Zhang M, Zhan X, Wei C, Elston RC, Lu Q (2014). A generalized genetic random field method for the genetic association analysis of sequencing data. Genet Epidemiol. 38:242-53.
  • Gore MO, Seliger SL, Defilippi CR, Nambi V, Christenson RH, Hashim IA, Hoogeveen RC, Ayers CR, Sun W, McGuire DK, Ballantyne CR, de Lemos JA (2014). Age-and sex-dependent upper reference limits for the high-sensitivity cardiac troponin T assay. J Am Coll Cardiol. 63:1441-8.
  • Jain N, Minhajuddin AT, Neeland IJ, Elsayed EF, Vega GL, Hedayati SS (2014). Association of urinary sodium-to-potassium ratio with obesity in a multiethnic cohort. Am J Clin Nutr. 99:992-8.
  • Lakoski SG, Kozlitina J (2014). Ethnic differences in physical activity and metabolic risk: The Dallas Heart Study. Med Sci Sports Exerc. 46:1124-32.
  • He Z, Zhang M, Zhan X, Lu Q (2014). Modeling and testing for joint association using a genetic random field model. Biometrics. 70:471-9.
  • Kozlitina J, Smagris E, Stender S, Nordestgaard BG, Zhou HH, Tybjærg-Hansen A, Hobbs HH, Cohen JC (2014). Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease. Nat Genet. 46: 352-6.
  • Petr EJ, Ayers CR, Pandey A, de Lemos JA, Powell-Wiley TM, Khera A, Lloyd-Jones DM, Berry JD (2014). Perceived lifetime risk for cardiovascular disease (from the Dallas Heart Study). Am J Cardiol. In press.
  • Paixao AR, Berry JD, Neeland IJ, Ayers CR, Rohatgi A, de Lemos JA, Khera A (2014). Coronary artery calcification and family history of myocardial infarction in the Dallas Heart Study. JACC Cardiovasc Imaging. 7:679-86.
  • Sun H, Wang S (2014). A power set-based statistical selection procedure to locate susceptible rare variants associated with complex traits with sequencing data. Bioinformatics. 30:2317-23.
  • Lin WY (2014). Association testing of clustered rare causal variants in case-control studies. PLoS One. 9(4):e94337.
  • Maroules CD, Khera A, Ayers C, Goel A, Peshock RM, Abbara S, King KS (2014). Cardiovascular outcome associations among cardiovascular magnetic resonance measures of arterial stiffness: the Dallas Heart Study. J Cardiovasc Magn Reson. 16:33.
  • Powell-Wiley TM, Ayers C, Agyemang P, Leonard T, Berrigan D, Barbash RB, Lian M, Das SR, Hoehner CM (2014). Neighborhood-level socioeconomic deprivation predicts weight gain in a multi-ethnic population: Longitudinal data from the Dallas Heart Study. Prev Med.  66:22-7.
  • Strickland AL, Rossetti HC, Peshock RM, Weiner MF (2014). Urinary Albumin to Creatinine Ratio as Potential Biomarker for Cerebral Microvascular Disease. Curr Neurovasc. Res. 11:242-7.
  • Brown ES, Hughes CW, McColl R, Peshock R, King KS, Rush AJ (2014). Association of depressive symptoms with hippocampal volume in 1936 adults. Neuropsychopharmacology. 39:770-9.
  • Paixao AR, Ayers CR, Rohatgi A, Das SR, de Lemos JA, Khera A, Lloyd-Jones D, Berry JD (2014). Cardiovascular lifetime risk predicts incidence of coronary calcification in individuals with low short-term risk: the Dallas Heart Study. J Am Heart Assoc. 3:e001280.
  • Rohatgi A, Khera A, Berry JD, Givens EG, Ayers CR, Wedkin KE, Neeland IJ, Yuhanna IS, Rader DR, de Lemos JA, Shaul PW (2014). HDL cholesterol efflux capacity and incident cardiovascular events. N Engl J Med. 371:2383-93.


  • Grundy SM, Neeland IJ, Turer AT, Vega GL (2013). Ethnic and gender susceptibility to metabolic risk. 12:110-6. Metab Syndr Relat Disord. 
  • Wang Y, Quagliarini F, Gusarova V, Gromada J, Valenzuela DM, Cohen JC, Hobbs HH (2013). Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostatis. P Natl Acad Sci USA 110:16109-14.
  • King KS, Peshock RM, Rossetti HC, McColl RW, Ayers CR, Hulsey KM, Das SR (2013). Effect of normal aging versus hypertension, abnormal body mass index, and diabetes mellitus on white matter hypertensity volume. Stroke. 45: 255-7.
  • Neeland IJ, Gupta S, Ayers CR, Turer AT, Rame JE, Das SR, Berry JD, Khera A, McGuire DK, Vega GL, Grundy SM, de Lemos JA, Drazner MH (2013).  Relation of regional fat distribution to left ventricular structure and function.  Circ Cardiovasc Imaging. 6: 800-7.
  • Grundy SM, Neeland IJ, Turer AT, Vega GL (2013). Waist circumference as measure of abdominal fat compartments. J Obes. Vol. 2013, Article ID 454285.
  • Maroules CD, Rosero E, Ayers C, Peshock RM, Khera A (2013). Abdominal Aortic Atherosclerosis at MR Imaging is Associated with Cardiovascular Events: The Dallas Heart Study. Radiology.  269:84-81.
  • Cusano NE, Maalouf NM, Wang PY, Zhang C, Cremers SC, Haney EM, Bauer DC, Orwoll ES, Bilezikian JP (2013). Normocalcemic Hyperparathyroidism and Hypoparathyroidism In Two Community-Based Non-Referral Populations. J Clin Endocr Metab. 98: 2734-41
  • Neeland IJ, Drazner MH, Berry JD, Ayers CR, Defilippi C, Seliger SL, Nambi V, McGuire DK, Omland T, de Lemos JA (2013). Biomarkers of chronic cardiac injury and hemodynamic stress identify a malignant phenotype of left ventricular hypertrophy in the general population. J Am Coll Cardiol 61:187-95.
  • Chen YC, Carter H, Parla J, Kramer M, Goes FS, Pirooznia M, Zandi PP, McCombie WR, Potash JB, Karchin R (2013). A hybrid likelihood model for sequence-based disease association studies. PLoS Genet 9e1003224.
  • Gankam-Kengne F, Ayers C, Khera A, de Lemos J, Maalouf NM (2013). Mild hyponatremia is associated with an increased risk of death in an ambulatory setting. Kidney Int 83:700-6.
  • Scott SA, Liu B, Nazarenko I, Martis S, Kozlitina J, Yang Y, Ramirez C, Kasai Y, Hyatt T, Peter I, Desnick RJ (2013). Frequency of the cholesteryl ester storage disease common LIPA E8SJM mutation (c.894g>a) in various racial and ethnic groups. Hepatology. 58: 958-65.
  • Powell-Wiley TM, Ayers CR, de Lemos JA, Lakoski SG, Vega GL, Grundy S, Das SR, Banks-Richard K, Albert MA (2013). Relationship between perceptions about neighborhood environment and prevalent obesity: data from the Dallas Heart Study. Obesity 21(1):E14-21.
  • King KS, Chen KX, Hulsey KM, McColl RW, Weiner MF, Nakonezny PA, Peshock RM (2013). White Matter Hyperintensities: Use of Aortic Arch Pulse Wave Velocity to Predict Volume Independent of Other Cardiovascular Risk Factors. Radiology. 267: 709-17
  • Sun J, Zheng Y, Hsu L (2013). A Unified Mixed-Effects Model for Rare-Variant Association in Sequencing Studies. Genet Epidemiol 37(4):334-44.
  • Neeland IJ, Winders BR, Ayers CR, Das SR, Chang AY, Berry JD, Khera A, McGuire DK, Vega GL, de Lemos JA, Turer AT (2013). Higher Natriuretic Peptide Levels Associate with a Favorable Adipose Tissue Distribution Profile. J Am Coll Cardiol. 62: 752-60
  • Gore MO, Luneburg N, Schwedhelm E, Ayers CR, Anderssohn M, Khera A, Atzler D, de Lemos JA, Grant PJ, McGuire DK, Boger RH (2013). Symmetrical dimethylarginine predicts mortality in the general population: observations from the Dallas Heart Study.  Arterioscler Thromb Vasc Biol. 33:2682-8.
  • Goel A, Peshock R, King KS, Whittemore A, McColl R (2013). A fully automated tool to identify the aorta and compute flow using Phase-contrast MRI: validation and application in a large population-based study. J Magn Reson Imaging. 2013 Sep 30.


  • Neeland IJ, Ayers CR, Rohatgi AK, Turer AT, Berry JD, Das SR, Vega GL, Khera A, McGuire DK, Grundy SM, de Lemos JA (2012). Associations of visceral and abdominal subcutaneous adipose tissue with markers of cardiac and metabolic risk in obese adults. E439-47 Obesity. 21:
  • Xing G, Lin CY, Xing C (2012). A comparison of approaches to control for confounding factors by regression models. Hum Hered 72:194-205.
  • Xing G, Lin CY, Wooding SP, Xing C (2012). Blindly using Wald's test can miss rare disease-causal variants in case-control association studies. Ann Hum Genet 76:168-77.
  • Turer AT, Browning JD, Ayers CR, Das SR, Khera A, Vega GL, Grundy SM, Scherer PE (2012). Adiponectin as an independent predictor of the presence and degree of hepatic steatosis in the Dallas Heart Study. J Clin Endocr Metab. 97(6):E982-6.
  • Luo L, Zhu Y, Xiong M (2012). A Novel Genome-Information Content-Based Statistic for Genome-Wide Association Analysis Designed for Next-Generation Sequencing Data. J Comput Biol 19(6):731-44.
  • Hulsey KM, Gupta M, King KS, Peshock RM, Whittemore AR, McColl RW (2012). Automated quantification of white matter disease extent at 3T: Comparison with volumetric readings. J Magn Reson Imaging36:305-11.
  • Yuan A, Cheng G, Zhou Y, Bentley A, Rotimi C (2012). A novel approach for the simultaneous analysis of common and rare variants in complex traits. Bioinform Biol Insights 6:1-9.
  • Mathieu RA, Powell-Wiley TM, Ayers CR, McGuire DK, Khera A, Das SR, Lakoski SG (2012). Physical activity participation, health perceptions, and cardiovascular disease mortality in a multiethnic population: The Dallas Heart Study. Am Heart J 163:1037-40.
  • Browning CR, Cagney KA, Iveniuk J (2012). Neighborhood stressors and cardiovascular health: Crime and C-reactive protein in Dallas, USA. Soc Sci Med. 75:1271-9.
  • Fujimoto N, Hastings JL, Bhella PS, Shibata s, Gandhi NK, Carrick-Ranson G, Palmer, D, Levine BD (2012). Effect of aging on left ventricular compliance and distensibility in healthy sedentary humans. J Physiol 590: 1871-1880.
  • Carrick-Ranson G, Hastings JL, Bhella PS, Shibata S, Fujimoto N, Palmer MD, Boyd K, Levine BD (2012). Effect of healthy aging on left ventricular relaxation and diastolic suction. Am J Physiol Heart Circ Physiol 303(3):H315-22.
  • Powell-Wiley TM, Banks-Richard K, Williams-King E, Tong L, Ayers CR, de Lemos JA, Gimpel N, Lee JJ, Dehaven MJ (2012). Churches as targets for cardiovascular disease prevention: comparison of genes, nutrition, exercise, wellness and spiritual growth (GoodNEWS) and Dallas County populations. J Public Health (Oxf) 35:99-106.
  • Gupta S, Matulevicius SA, Ayers CR, Berry JD, Patel PC, Markham DW, Levine BD, Chin KM, de Lemos JA, Peshock RM, Drazner MH (2012). Left atrial structure and function and clinical outcomes in the general population. Eur Heart J 34:278-85.
  • Gupta NK, de Lemos JA, Ayers CR, Abdullah S, McGuire DK, Khera A (2012). The relationship between C-Reactive protein and atherosclerosis differs on the basis of body mass index: The Dallas Heart Study. J Am Coll Cardiol 60(13): 1148-55.
  • Zhan H, Xu S (2012). Adaptive ridge regression for rare variant detection. PLoS One 7:e44173.
  • Luo L, Zhu Y, Xiong M (2012). Quantitative trait locus analysis for next-generation sequencing with the functional linear models. J Med Genet. 49:513-24.
  • Cheung YH, Wang G, Leal SM, Wang S (2012). A fast and noise-resilient approach to detect rare-variant associations with deep sequencing data for complex disorders. Genet Epidemiol 36:675-85.
  • Epstein MP, Duncan R, Jiang Y, Conneely KN, Allen AS, Satten GA (2012). A permutation procedure to correct for confounders in case-control studies including tests of rare variation. Am J Hum Genet91:215-23.
  • Luo L, Zhu Y, Xiong M (2012). Smoothed functional principal component analysis for testing association of the entire allelic spectrum of genetic variation. Eur J Hum Genet 21:217-24.
  • Neeland IJ, Turer AT, Ayers CR, Powell-Wiley TM, Vega GL, Farzaneh-Far R, Grundy SM, Khera A, McGuire DK, de Lemos JA (2012). Dysfunctional adiposity and the risk of prediabetes and type 2 diabetes in obese adults. JAMA 308:1150-9.
  • King KS, Peshock RM, Warren MW, Alhilali L, Husley K, McColl R, Weiner MF, Ayers C, Whittemore A (2012). Evaluation of a practical visual MRI rating scale of brain white matter hyperintensities for clinicians based on largest lesion size regardless of location. Am J Neuroradiol 34(4):797-801.
  • Barnett IJ, Lee S, Lin X (2012). Detecting rare variant effects using extreme phenotype sampling in sequence association studies. Genet Epidemiol 37:142-51.
  • Martinez-Rumayor AA, de Lemos JA, Rohatgi AK, Ayers CR, Powell-Wiley TM, Lakoski SG, Berry JD, Khera A, Das SR (2012). Addition of highly sensitive troponin T and N-terminal pro-B-type natriuretic peptide to electrocardiography for detection of left ventricular hypertrophy: results from the Dallas Heart Study. Hypertension 61:105-11.
  • Lucarelli RT, Peshock RM, McColl R, Hulsey K, Ayers C, Whittemore AR, King KS (2012). MR imaging of hippocampal asymmetry at 3T in a multiethnic, population-based sample: results from the Dallas Heart Study. Am J Neuroradiol 34(4):752-7.
  • Kozlitina J, Garcia CK (2012). Red blood cell size is inversely associated with leukocyte telomere length in a large multi-ethnic population. PLoS One 7(12):e51046.
  • Lee S, Wu MC, Lin X (2012). Optimal tests for rare variant effects in sequencing association studies. Biostatistics 13:762-75.
  • Chen LQ, de Lemos JA, Das SR, Ayers CR, Rohatgi A (2012). Soluble ST2 is associated with all-cause and cardiovascular mortality in a population-based cohort: the Dallas Heart Study. Clin Chem 59:536-46.

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  • Chang AY, Ayers C, Minhajuddin A, Jain T, Nurenberg P, de Lemos JA, Wild RA, Auchus RJ. Polycystic ovarian syndrome and subclinical atherosclerosis among women of reproductive age in the Dallas heart study (2011). 74(1):89-96. Clin Endocrinol (Oxf)
  • Powell TM, de Lemos JA, Banks K, Ayers CR, Rohatgi A, Khera A, McGuire DK, Berry JD, Albert MA, Vega GL, Grundy SM, Das SR. Body size misperception: a novel determinant in the obesity epidemic (2010). Arch Intern Med, 170(18):1695-7.
  • Bernstein IH, Lacritz L, Barlow CE, Weiner MF, DeFina LF. Psychometric evaluation of the Montreal Cognitive Assessment (MoCA) in three diverse samples (2011) Clin Neuropsychol (1):119-26.
  • Banks K, Puttagunta D, Murphy S, Lo M, McGuire DK, de Lemos JA, Chang AY, Grundy SM, Khera A. Clinical characteristics, vascular function, and inflammation in women with angina in the absence of coronary atherosclerosis: the Dallas Heart Study (2011). JACC Cardiovasc Imaging 4(1):65-73.
  • Kozlitina J, Boerwinkle E, Cohen JC, Hobbs HH. Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance (2011). Hepatology 53(2):467-74.
  • Vaeth PC, Willett, DL. Illness Risk Perceptions and Trust: The Association with Blood Pressure Self-measurement (2011). Am J Health Behav 35(1):105-117.
  • Gupta S, Rohatgi A, Ayers CR, Patel PC, Matulevicius SA, Peshock RM, Markham DW, de Lemos JA, Berry JD, Drazner MH. Risk scores versus natriuretic peptides for identifying prevalent stage B heart failure (2011). Am Heart J 161:923-930.
  • Luo L, Boerwinkle E, Xiong M (2011). Association studies for next-generation sequencing. Genome Res 21:1099-108.
  • Deo RC, Wilson JG, Xing C, Lawson K, Kao WH, Reich D, Tandon A, Akylbekova E, Patterson N, Mosley TH Jr, Boerwinkle E, Taylor HA Jr. Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans (2011). PLoS One 6(1):e14581.
  • Matulevicius S, Huff LC, Szczepaniak LS, Ayers CR, Budoff M, McColl R, Khera A, Peshock RM. Potential of electron beam computed tomography for coronary artery calcium screening to evaluate fatty liver: comparison with 1H magnetic resonance spectroscopy in the Dallas Heart Study (2011). J Investig Med 59:780-786.
  • Grodin JL, Powell-Wiley TM, Ayers CR, Kumar DS, Rohatgi A, Khera A, McGuire DK, de Lemos JA, Das SR. Circulating levels of matrix metalloproteinase-9 and abdominal aortic pathology: From the Dallas Heart Study (2011). Vasc Med 16(5): 339-45
  • Friedman DJ, Kozlitina J, Genovese G, Joq P, Pollak MR (2011). Population-based risk assessment of APOL1 on renal disease. J Am Soc Nephrol 22(11):2098-105.
  • Chen LQ, Rohatgi A, Ayers CR, Das SR, Khera A, Berry JD, McGuire DK, de Lemos JA (2011). Race-specific associations of myeloperoxidase with atherosclerosis in a population-based sample: The Dallas Heart Study. Atherosclerosis 219(2): 833-8.
  • Powell-Wiley TM, Ayers CR, Richard KB, Berry JD, Khera A, Lakoski SG, McGuire DK, de Lemos JA (2011). Disparities in counseling for lifestyle modification among obese adults: insights from the Dallas Heart Study. Obesity (Silver Spring) 2011 Aug 4.
  • Nguyen AB, Rohatgi A, Garcia CK, Ayers CR, Das SR, Lakoski SG, Berry JD, Khera A, McGuire DK, de Lemos JA (2011). Interactions between smoking, pulmonary surfactant protein B, and atherosclerosis in the general population: the Dallas Heart Study. Arterioscler Thromb Vasc Biol 31(9):2136-43.
  • Turer AT, Khera A, Ayers CR, Turer CB, Grundy SM, Vega GL, Scherer PE (2011). Adipose tissue mass and location affect circulating adiponectin levels. Diabetologia 54(10):2515-24.
  • Rohatgi A, Patel P, Das SR, Ayers CR, Khera A, Martinez-Rumayor A, Berry JD, McGuire DK, de Lemos JA (2011). Association of growth differentiation factor-15 with coronary atherosclerosis and mortality in a young, multiethnic population: observations from the Dallas Heart Study. Clin Chem 58(1):172-82.
  • Hedayati SS, Minhajuddin AT, Ijaz A, Moe OW, Elsayed EF, Reilly RF, Huang CL (2011). Association of Urinary Sodium/Potassium Ratio with Blood Pressure: Sex and Racial Differences. Clin J Am Soc Nephrol 7(2):315-22.
  • Wu MC, Lee S, Cai T, Li Y, Boehnke M, Lin X (2011). Rare-variant association testing for sequencing data with the sequence kernel association test. Am J Hum Genet 89:82-93.
  • Rosetti HC, Lacritz LH, Cullum CM, Weiner MF (2011). Normative data for the Montreal Cognitive Assessment (MoCA) in a population-based sample. Neurology 77:1272-1275.
  • Yi N, Liu N, Zhi D, Li J (2011). Hierarchical generalized linear models for multiple groups of rare and common variants: jointly estimating group and individual variant effects. PloS Genet 7(12):e1002382,

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  • Khouri MG, Peshock RM, Ayers CR, de Lemos JA, Drazner MH. A four-tiered classification of left ventricular hypertrophy based on left ventricular geometry: the Dallas Heart Study (2010)., 3(2):129-31. Circ Cardiovasc Imaging
  • He S, McPhaul C, Li JZ, Garuti R, Kinch L, Grishin NV, Cohen JC, Hobbs HH. (2010) A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis. J Biol Chem 285: 6706-6715.
  • Xing C, Cohen JC, Boerwinkle E. A Weighted False Discovery Rate Control Procedure Reveals Alleles at FOXA2 that Influence Fasting Glucose Levels (2010). Am J Hum Genet 86(3):440-446.
  • Castillo L, Rohatgi A, Ayers CR, Owens AW, Das SR, Khera A, McGuire DK, de Lemos JA. Associations of Four Circulating Chemokines With Multiple Atherosclerosis Phenotypes in a Large Population-Based Sample: Results From the Dallas Heart Study (2010). J Interferon Cytokine Res, 30(5):339-47.
  • Maxwell TJ, Bendall ML, Staples J, Jarvis T, Crandall KA (2010). Phylogenetics applies to genotype/phenotype association and selection analyses with sequence data from angptl4 in humans. Int J Mol Sci 11:370-85.
  • Liu DJ, Leal SM (2010). A novel adaptive method for the analysis of next-generation sequencing data to detect complex trait associations with rare variants due to gene main effects and interactions. PLoS Genet 6:e1001156.
  • Gupta S, Berry JD, Ayers CR, Matulevicius SA, Peshock RM, Patel PC, Markham DW, Drazner MH. Association of Health Aging and Body Composition (ABC) Heart Failure score with cardiac structural and functional abnormalities in young Individuals (2010). Am Heart J (5):817-24.
  • Gupta S, Berry JD, Ayers CR, Peshock RM, Khera A, de Lemos JA, Patel PC, Markham DW, Drazner MH. Left ventricular hypertrophy, aortic wall thickness, and lifetime predicted risk of cardiovascular disease: the Dallas Heart Study (2010). JACC Cardiovasc Imaging 3(6):605-13.
  • de Lemos JA, Drazner MH, Omland T, Ayers CR, Khera A, Rohatgi A, Hashim I, Berry JD, Das SR, Morrow DA, McGuire DK. Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population (2010). JAMA 304(22):2503-12.
  • Owens AW, Matulevicius S, Rohatgi A, Ayers CR, Das SR, Khera A, McGuire DK, de Lemos JA. Circulating lymphotoxin β receptor and atherosclerosis: observations from the Dallas Heart Study (2010). Atherosclerosis 212(2):601-6.

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  • Romeo S, Yin W, Kozlitina J, Pennacchio LA, Boerwinkle E, Hobbs HH, Cohen JC (2009). Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans.  119(1):70-9. J Clin Invest
  • Rohatgi A, Ayers CR, Khera A, McGuire DK, Das SR, Matulevicius S, Timaran CH, Rosero EB, de Lemos JA (2009). The association between peptidoglycan recognition protein-1 and coronary and peripheral atherosclerosis: Observations from the Dallas Heart Study. Atherosclerosis 203:569-575.
  • Chang AY, FitzGerald SJ, Cannaday J, Zhang S, Patel A, Palmer MD, Reddy GP, Ordovas KG, Stillman AE, Janowitz W, Radford NB, Roberts AJ, Levine BD (2009). Cardiovascular risk factors and coronary atherosclerosis in retired National Football League players. Am J Cardiol 104-805-11.
  • Oeffinger KC, Adams-Huet B, Victor RG, Church TS, Snell PG, Dunn AL, Eshelman-Kent DA, Ross R, Janiszewski PM, Turoff AJ, Brooks S, Vega GL (2009). Insulin resistance and risk factors for cardiovascular disease in young adult survivors of childhood acute lymphoblastic leukemia. J Clin Oncol 27:3698-704.
  • Arking DE, Khera A, Xing C, Kao WH, Post W, Boerwinkle E, Chakravarti A (2009). Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population. PLoS ONE 4(1):e4333.
  • Tsimikas S, Clopton P, Brilakis ES, Marcovina SM, Khera A, Miller ER, de Lemos JA, Witzum JL (2009) Relationship of oxidized phospholipids on apolipoprotein B-100 particles to race/ethnicity, apolipoprotein(a) isoform size, and cardiovascular risk factors: results from the Dallas Heart Study. Circulation 119(13):1711-9.
  • Fahmi S, Yang C, Esmail S, Hobbs HH, Cohen JC (2008) Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes. Hum Mol Genet 17:2101-2107.
  • Khera A, Vega GL, Das SR, Ayers C, McGuire DK, Grundy SM, de Lemos JA. Sex differences in the relationship between C-reactive protein and body fat (2009). J Clin Endocrinol Metab 94(9):3251-8.
  • Lindsey JB, de Lemos JA, Cipollone F, Ayers CR, Rohatgi A, Morrow DA, Khera A, McGuire DK. (2009) Association Between Circulating Soluble Receptor for Advanced Glycation End Products (sRAGE) and Risk for Atherosclerosis: Observations from the Dallas Heart Study. Diabetes Care 32(7):1218-20.
  • Patel PC, Ayers CR, Murphy SA, Peshock R, Khera A, de Lemos JA, Balko JA, Gupta S, Mammen PP, Drazner MH, Markham DW. Association of cystatin C with left ventricular structure and function: the Dallas Heart Study (2009). Circ Heart Fail (2):98-104.
  • Rohatgi A, Owens AW, Khera A, Ayers CR, Banks K, Das SR, Berry JD, McGuire DK, de Lemos JA (2009). Differential associations between soluble cellular adhesion molecules and atherosclerosis in the Dallas Heart Study: a distinct role for soluble endothelial cell-selective adhesion molecule. Arterioscler Thromb Vasc Biol 29:1684-90.
  • Lakoski SG, Lagace TA, Cohen JC, Horton JD, Hobbs HH. Genetic and metabolic determinants of plasma PCSK9 levels (2009).J Clin Endocrinol Metab 94:2537-43.
  • De Lemos JA, McGuire DK, Khera A, Das SR, Murphy SA, Omland T, Drazner MH (2009). Screening the population for left ventricular hypertrophy and left ventricular systolic dysfunction using natriuretic peptides: results from the Dallas Heart Study. Am Heart J 157(4):746-53.
  • Patel MJ, de Lemos JA, McGuire DK, See R, Lindsey JB, Murphy SA, Grundy SM, Khera A (2009). Evaluation of coronary artery calcium screening strategies focused on risk categories: the Dallas Heart Study. Am Heart J 157(6):1001-9.

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  • Baber U, de Lemos JA, Khera A, McGuire DK, Omland T, Toto RD, Hedayati SS (2008) Non-traditional risk factors predict coronary calcification in chronic kidney disease in a population-based cohort. 73: 615-621. Kidney Int
  • Brilakis EM, Khera A, McGuire DK, See R, Banerjee S, Murphy SA, de Lemos JA (2008) Influence of race and sex on lipoprotein-associated phospholipase A2 levels: Observations from the Dallas Heart Study. Atherosclerosis 119(1):110-5.
  • See R, Lindsey JB, Patel MJ, Ayers CR, Khera A, McGuire DK, Grundy SM, de Lemos JA (2008). Application of the screening for Heart Attack Prevention and Education Task Force recommendations to an urban population: observations from the Dallas Heart Study. Archives Int Med 168(10):1055-62.
  • Markham DW, Dries DL, King LP, Leonard D, Yancy CW, Peshock RM, Willett D, Cooper RS, Drazner MH (2008) Blacks and whites have a similar prevalence of reduced left ventricular ejection fraction in the general population: The Dallas Heart Study. Am Heart J 155(5):876-82.
  • Maroules CD, McColl R, Khera A, Peshock RM. Interstudy Variability of SSFP Cine magnetic resonance: impact of magnetic field strength and parallel imaging(2008). J Magn Reson Imaging 27(5): 1139-45.
  • Romeo S, Kozlitina J, Xing C, Pertsemlidis A, Cox D, Pennacchio LA, Boerwinkle E, Cohen JC, Hobbs HH (2008). Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet 40:1461-5.
  • Victor RG, Leonard D, Hess P, Bhat DG, Jones J, Vaeth, PAC, Ravenell J, Freeman A, Wilson RP, and Haley RW: Factors associated with hypertension awareness, treatment, and control in Dallas County Texas. Archives Int Med 168(12):1285-93.
  • Chen K, Lindsey JB, Khera A, de Lemos JA, Ayers CR, Goyal A, Vega GL, Murphy SA, Grundy SM, McGuire DK (2008). Independent associations between metabolic syndrome, diabetes mellitus and atherosclerosis : observations from the Dallas Heart Study. Diab Vasc Dis Res 5(2):96-101.
  • Grundy SM, Adams-Huet B, Vega GL (2008). Variable contributions of fat content and distribution to metabolic syndrome risk factors. Metab Syndr Relat Disord 6(4):281-8.
  • Matulevicius S, Rohatgi A, Khera A, Das SR, Owens A, Ayers CR, Timaran CH, Rosero EB, Drazner MH, Peshock RM, de Lemos JA (2008). The association between plasma caspase-3, atherosclerosis, and vascular function in the Dallas Heart Study. Apoptosis 13(10):1281-9
  • Brilakis ES, Khera A, Saeed B, Banerjee S, McGuire DK, Murphy SA, de Lemos JA (2008). Association of lipoprotein-associated phospholipase A2 mass and activity with coronary and aortic atherosclerosis: findings from the Dallas Heart Study. Clin Chem 54(12): 1975-81.
  • Das SR, Abdullah SM, Leonard D, Drazner MH, Khera A, McGuire DK, de Lemos JA (2008). Association between renal function and circulating levels of natriuretic peptides (from the Dallas Heart Study). Am J Cardiol 102(10):1394-8.
  • Albert MA, Ravenell J, Glynn RJ, Khera A, Halevy N, de Lemos JA (2008). Cardiovascular risk indicators and perceived race/ethnic discrimination in the Dallas Heart Study. Am Heart J 156(6):1103-9.

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  • Abdullah SM, Khera A, Leonard D, Das SR, Canham RM, Kamath SA, Vega GL, Grundy SM, McGuire DK, de Lemos JA (2007) Sex differences in the association between leptin and CRP: results from the Dallas Heart Study. 195: 404-10. Atherosclerosis
  • Chang AY, Abdullah SM, Jain T, Stanek HG, Das SR, McGuire DK, Auchus RJ, de Lemos JA (2006) Association among androgens, estrogens and natriuretic peptides in young women: observations from the Dallas Heart Study. J Am Coll Cardiol 49: 109-16.
  • Abedin M, Omland T, Ueland T, Khera A, Aukrust P, Murphy SA, Jain T, Gruntmanis U, McGuire DK, de Lemos JA (2007) Relation of osteoprotegerin to coronary calcium and aortic plaque (from the Dallas Heart Study). Am J Cardiol 99(4): 513-18.
  • Romeo S, Pennacchio LA, Fu Y, Boerwinkle E, Tybjaerg-Hansen A, Hobbs HH, Cohen JC (2007) Population-based resequencing ofANGPTL4 reveals variations that reduce triglycerides and increase HDL in Caucasians. Nat Genet 39:513-516.
  • Horton, JD, Cohen JC, Hobbs HH. (2007) Molecular biology of PCSK9: its role in LDL metabolism. Trends Biochem Sci 32: 71-7
  • Chandalia M, Grundy SM, Adams-Huet B, Abate N (2007) Ethnic differences in the frequency of ENPP1/PC1 121Q genetic variant in the Dallas Heart Study cohort. J Diabetes Complications 21:143-8.
  • Rame JE, Drazner MH, Post W, Peshock R, Lima J, Cooper RS, Dries DL (2007) Corin I555(P568) allele is associated with enhanced cardiac hypertrophic response to increased systemic afterload. Hypertension 49(4): 857-64.
  • Vega GL, Chandalia M, Szczepaniak LS, Grundy SM (2007) Metabolic correlates of non-alcoholic fatty liver in women and men. Hepatology 46:716-722.
  • Omland T, Drazner MH, Ueland T, Abedin M, Murphy SA, Aukrust P, de Lemos JA (2007). Plasma osteoprotegerin levels in the general population: relation to indices of left ventricular structure and function. Hypertension 49(6):1392-8.
  • Mehta SK, Rame JE, Khera A, Murphy SA, Canham RM, Peshock RM, de Lemos JA, Drazner MH. (2007) Left Ventricular Hypertrophy, Subclinical Atherosclerosis, and Inflammation. Hypertension 49(6): 1385-91.
  • See R, Abdullah SM, McGuire DK, Khera A, Patel MJ, Lindsey J, Grundy SM, de Lemos JA (2007). The Association of Differing Measures of Overweight and Obesity with Prevalent Atherosclerosis: the Dallas Heart Study. J Am Coll Cardiol 50(8):752-9.
  • Phillips B, de Lemos JA, Patel M, McGuire DK, Khera A (2007) Relation of Family History of Myocardial Infarction and the Presence of Coronary Arterial Calcium in Various Age and Risk-Factor Groups. Am J Cardiol 99(6):825-9.
  • McPherson R, Pertsemlidis A, Kavaslar N, Stewart A, Roberts R, Cox DR, Hinds DA, Pennacchio LA, Tybjaerg-Hansen A, Folsom AR, Boerwinkle E, Hobbs HH, Cohen JC (2007) A common allele on chromosome 9 associated with coronary heart disease. Science 316:1488-91.
  • Spirin V, Schmidt S, Pertsemlidis A, Cooper RS, Cohen JC, Sunyaev SR (2007) Common single-nucleotide polymorphisms act in concert to affect plasma levels of high-density lipoprotein cholesterol. Am J Hum Genet 81:1298 - 1303.
  • Zirlik A, Abdullah SM, Gerdes N, MacFarlane L, Schönbeck U, Khera A, McGuire DK, Vega GL, Grundy S, Libby P, de Lemos JA (2007). Interleukin-18, the metabolic syndrome, and subclinical atherosclerosis: results from the Dallas Heart Study. Arterioscler Thromb Vasc Biol 27:2043-9.
  • Patel MJ, de Lemos JA, Philips B, Murphy SA, Vaeth PC, McGuire DK, Khera A (2007) Implications of family history of myocardial infarction in young women. Am Heart J 154:454-60
  • Hess PL, Reingold JS, Jones J, Fellman MA, Knowles P, Ravenell JE, Kim S, Raju J, Ruger E, Clark S, Okoro C, Ogunji O, Knowles P, Leonard D, Wilson RP, Haley RW, Ferdinand KC, Freeman A, Victor RG (2007) Barbershops as hypertension detection, referral, and follow-up centers for black men. Hypertension 49:1040-6.
  • McGavok JM, Lingvay K, Zib I, Tillery T, Salas N, Underg R, Levine BD, Raskin P, Victor RG, Szczepaniak LS (2007) Cardiac steatosis in diabetes mellitus: a  1 H-magnetic resonance spectroscopy study. Circulation 116(10): 1170-5.


  • Khera A, de Lemos JA, Peshock RM, Lo HS, Stanek HG, Murphy SA, Wians FH, Grundy SM, McGuire DK (2006) Relationship between C-reactive protein and sub-clinical atherosclerosis: the Dallas Heart Study. 113: 38-43 Circulation
  • Das SR, Vaeth PA, Stanek HG, de Lemos JA, Dobbins RL, McGuire DK (2006) Increased cardiovascular risk associated with diabetes in Dallas County. Am Heart J 151:1087-93.
  • Hollier J, Martin DF, Bell DM, Li JL, Chirachanchai MG, Menon DV, Leonard D, Victor RG, Cooper RS, Auchus RJ (2006) Epithelial sodium channel allele T594M is not associated with blood pressure or blood pressure response to amiloride. Hypertension 47: 428-33.
  • Cohen JC, Boerwinkle E, Mosley TH, Hobbs HH (2006) Sequence variations in PCSK9 associated with low plasma LDL confer protection against coronary heart disease. N Engl J Med, 354: 1264-72.
  • Chung AK, Das SR, Leonard D, Peshock RM, Kazi F, Abdullah SM, Canham RM, Levine B, Drazner MH (2006) Women have a higher left ejection fraction than men independent of their smaller left ventricular volume: The Dallas Heart Study. Circulation 113: 1597-604.
  • Wallace TW, Abdullah SM, Drazner MH, Das SR, Khera A, McGuire DK, Wians F, Sabatine MS, Morrow DA, de Lemos JA (2006) Prevalence and determinants of Troponin T elevation in the general population. Circulation 16: 1958-65.
  • Li JL, Canham RM, Vongpatanasin W, Leonard D, Auchus RJ, Victor RG (2006) Do allelic variants in alpha2A and alpha2C adrenergic receptors predispose to hypertension in blacks? Hypertension 47: 1140-6.
  • Zhao Z, Tuakli-Wosornu Y, Lagace TA, Kinch L, Grishin N, Horton J, Cohen JC, Hobbs HH (2006) Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote. Am J Hum Genet 79:514-23
  • Vega GLAdams-Huet BPeshock RWillett DShah BGrundy SM. (2006) Influence of body fat content and distribution on variation in metabolic risk. J Clin Endocrinol Metab 29: 1414-6
  • Browning J (2006) Statins and hepatic steatosis: Perspectives from the Dallas Heart Study. Hepatology 44: 466-471.
  • 36. Canham RM, Das SR, Abdullah SM, Chung AK, Li JL, Victor RG, Auchus RJ, Drazner MH (2006) Alpha 2cDel322-324 and B1Arg389 adrenergic polymorphisms are not associated with reduced left ventricular ejection fraction or increased left ventricular volume. J Am Coll Cardiol 49: 274-276.
  • Romeo S, Cohen JC, Hobbs HH. (2006) No association between polymorphism in PEMT (V175M) and hepatic triglyceride content in the Dallas Heart Study. FASEB J 20(12): 2180.

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  • Szczepaniak LS, Nurenberg P, Leonard D, Browning JD, Reingold JS, Grundy SM, Hobbs HH, Dobbins RL (2005) Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population.  288:E462-8. Am J Physiol Endocrinol Metab
  • Cohen J, Pertsemlidis A, Kotowski IK, Graham R, Garcia CK, Hobbs HH (2005) Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9. Nat Genet 37: 161-165.
  • Kramer H, Toto R, Peshock R, Cooper R, Victor RG (2005) Association between chronic kidney disease and coronary artery calcification: The Dallas Heart Study. J Am Soc Nephrol 16:507-13.
  • Vaeth PA, Willett DL (2005) Level of acculturation and hypertension among Dallas County Hispanics: findings from the Dallas Heart Study. Ann Epidemiol 15:373-80.
  • Guerra R, Yu Z, Marcovina S, Peshock R, Cohen JC, Hobbs HH (2005) Lipoprotein(a) and apolipoprotein(a) isoforms: no association with coronary artery calcification in the Dallas Heart Study. Circulation 111:1471-9.
  • Abate N, Chandalia M, Satija P, Adama-Huet B, Grundy SM, Sandeep S, Radha V, Deepa R, Mohan V (2005) ENPP1/PC-1 K121Q polymorphism and genetic susceptibility to type 2 diabetes. Diabetes 54: 1207-13.
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  • Khera A, McGuire DK, Murphy SA, Stanek HG, Das SR, Vongpatanasin W, Wians FH Jr, Grundy SM, de Lemos JA (2005) Race and gender differences in C-reactive protein levels. J Am Coll Cardiol 46: 464-9.
  • White PC (2005) Genotypes at 11β-hydroxysteroid dehydrogenase type 11B1 and hexose-6-Phosphate Dehydrogenase Loci are not risk factors for apparent cortisone reductase deficiency in a large population-based sample. J Clin Endo Metab 90: 5880-5883.
  • De Lemos JA, Zirlik A, Schonbeck U, Varo N, Murphy SA, Khera A, McGuire DK, Stanek HG, Lo HS, Nuzzo R, Morrow DA, Peshock R, Libby P (2005) Associations between soluble CD40 ligand, atherosclerosis risk factors, and subclinical atherosclerosis: results from the Dallas Heart Study. Arterioscler Thromb Vasc Biol 25: 2192-6.
  • Das SR, Drazner MH, Dries DL, Vega GL, Stanek HG, Abdullah SM, Canham RM, Chung AK, Leonard D, Wians FH Jr, de Lemos JA (2005) Impact of body mass and body composition on circulating levels of natriuretic peptides: results from the Dallas Heart Study. Circulation 112: 2163-8.
  • Dries DL, Victor RG, Rame JE, Cooper RS, Wu X, Zhu X, Leonard D, Ho SI, Wu Q, Post W, Drazner MH (2005) Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension. Circulation 112: 2403-10.
  • Abdullah SM, Khera A, Das SR, Stanek HG, Canham RM, Chung AK, Morrow DA, Drazner MH, McGuire DK, de Lemos JA (2005) Relation of coronary atherosclerosis determined by electron beam computed tomography and plasma levels of n-terminal pro-brain natriuretic peptide in a multiethnic population-based sample (the Dallas Heart Study). Am J Cardiol 96:1284-9.
  • Reingold JS, McGavock JM, Kaka S, Tillery T, Victor RG, Szczepaniak LS (2005) Determination of triglyceride in the human myocardium by magnetic resonance spectroscopy: reproducibility and sensitivity of the method. Am J Physiol Endocrinol Metab 289: E935-9. (Recruitment Source)
  • Cohen JC, Pertsemlidis A, Fahmi S, Esmail S, Vega GL, Grundy SM, Hobbs HH (2005) Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma LDL levels. Proc Natl Acad Sci USA 103: 1810-15.
  • Kotowski IK, Pertsemlidis A, Luke A, Cooper RS, Vega GL, Cohen JC, Hobbs HH (2005) A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol. Am J Hum Genet, 78: 410-22.

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  • Victor RG, Haley RW, Willett D, Peshock RM, Vaeth PC, Leonard D, Basit M, Cooper RS, Iannachione VG, Visscher W, Staab J, Hobbs HH for the Dallas Heart Study Investigators (2004) The Dallas Heart Study: a population-based probability sample for the multidisciplinary study of ethnic differences in cardiovascular health.  93:1473-80.Am J Cardiol
  • Spranger CB, Ries AJ, Berge CA, Radford NB, Victor RG (2004) Identifying gaps between guidelines and clinical practice in the evaluation and treatment of hypertension. American Journal of Medicine117:14-8.
  • Jain T, Peshock R, McGuire DK, Willett D, Yu Z, Vega GL, Guerra R, Grundy SM, Hobbs HH and the Dallas Heart Study Investigators (2004) African Americans and Caucasians have a similar prevalence of coronary calcium in the Dallas Heart Study. J Am Coll Cardiol 44: 1011-7.
  • Deo R, Khera A, Mcguire DK, Murphy SA, Meo Neto J, Morrow DA, de Lemos JA (2004) Association between plasma levels of monocyte chemoattractant protein-1, traditional cardiovascular risk factors and subclinical atherosclerosis. J Am Coll Cardiol 44:1812-8.
  • Cohen JC, Kiss RS, Pertsemlidis A, Marcel YL, McPherson R, Hobbs HH (2004) Multiple rare alleles contribute to low plasma levels of HDL cholesterol. Science 305: 869-872.
  • Browning JD, Szczepaniak LS, Dobbins R, Nuremberg P, Horton JD, Cohen JC, Grundy SM, Hobbs HH (2004) Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 40: 1387-95.
  • Wilund K, Yu L, Xu F, Vega G, Grundy SM, Cohen JC, Hobbs HH (2004) Plant sterol levels are not associated with atherosclerosis in mice and men. Arterioscler Thromb Vasc Biol 24:2326-32

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  • Pennacchio LA, Olivier M, Hubacek JA, Krauss RM, Rubin EM, and Cohen JC (2002) Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels. 11:3031-3038. Hum Mol Genet


  • Pennacchio LA, Olivier M, Hubacek JA, Cohen JC, Cox DR, Fruchart JC, Krauss RM, and Rubin EM (2001) An apolipoprotein identified through comparative sequence analysis influences plasma triglyceride levels in humans and mice. 294:169-173. Science

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