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A protein receptor called PAQR4 found within fat cells appears to act as a sensor for ceramides, waxy lipids whose overabundance has been linked to a variety of metabolic disorders and cancers, a study led by UT Southwestern Medical Center researchers suggests.

A drug that targets a protein known as phosphatidylserine boosted the response rate for hepatocellular carcinoma (HCC) patients receiving immunotherapy without compromising their safety, according to results of a phase two clinical trial conducted by UT Southwestern Medical Center.

The scorching heat can be inescapable this time of year, and as temperatures hover around triple digits, experts at UT Southwestern Medical Center caution that uncomfortable weather can escalate to dangerous health conditions.

Obstructive sleep apnea (OSA) is linked to an increased risk of cardiovascular disease in adults, even those younger than 40, researchers at UT Southwestern Medical Center found.

The role of the microbiome in intestinal and systemic health has garnered close attention among researchers for many years. Now evidence is mounting that this collection of microorganisms in the human gut can also impact a person’s neurological and emotional health.

A research team at UT Southwestern has been approved for a five-year, $7 million funding award from the Patient-Centered Outcomes Research Institute (PCORI).

Heart failure patients may one day be able to restore cardiac function with medications that revive the body’s ability to regenerate heart muscle, a novel study at UT Southwestern Medical Center suggests.

– An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world’s most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse.

A statistical tool designed to analyze 11 characteristics of postmortem brains reliably diagnosed a common neurodegenerative disease known as essential tremor (ET), a study led by researchers at UT Southwestern Medical Center and Columbia University shows.

Studies analyze blue light cystoscopy, irregularities in brain activity, the origins of abnormal bone formations, and HIV transcription.