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2025 Article Archive

Ribosome level changes detected in early brain development

 

A team led by UT Southwestern Medical Center scientists has identified a specific stage of neurodevelopment when differentiating neural cells produce fewer ribosomes, which are responsible for making proteins.

Circadian gene may be a key to humans’ unique cognitive abilities

 

The CLOCK gene, which serves as a master controller of circadian rhythms, may play a key role in the extraordinary cognitive abilities of humans as well as neuropsychiatric disorders that afflict them, UT Southwestern Medical Center researchers report.

UT Southwestern is best hospital in DFW for ninth straight year

 

UT Southwestern Medical Center is the No. 1 hospital in Dallas-Fort Worth for the ninth consecutive year and ranks among the nation’s top hospitals for care in 12 specialties – the most of any hospital in Texas, according to U.S. News & World Report’s annual Best Hospitals list released today.

UTSW builds AI-driven system to improve data collection 

 

A multidisciplinary team at UT Southwestern Medical Center has developed an artificial intelligence (AI)-enabled pipeline that can quickly and accurately extract relevant information from complex, free-text medical records. The team’s novel approach, featured in npj Digital Medicine, could dramatically reduce the time needed to create analysis-ready data for research studies.

UTSW researchers identify new immunotherapy target

 

Researchers at UT Southwestern Medical Center have discovered how a hormone interacts with a receptor on the surface of immune cells to shield cancer cells from the body’s natural defenses. The findings, published in Nature Immunology, could lead to new immunotherapy approaches for treating cancer as well as potential treatments for inflammatory disorders and neurologic diseases.

Study sheds light on cilia’s function in cells, role in diseases

 

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the surfaces of many cell types that generate their movement.

UTSW Research: Anaphylaxis hospital stays, LDL-lowering drug, and more

 

A team of researchers including UT Southwestern Medical Center Pediatrics faculty members Jo-Ann Nesiama, M.D., Professor, and Geetanjali Srivastava, M.D., M.P.H., Associate Professor, collected data on 5,641 ED visits for pediatric anaphylaxis between 2016 and 2019 from 30 hospitals in the U.S. and one in Canada.

UTSW Research: Treating shoulder pain, aortic valve procedures, and more

 

Millions of Americans have chronic shoulder pain, which can have a significant impact on quality of life. Although some get relief from medications, physical therapy, or joint injections, those with persistent pain often pursue more aggressive treatments such as surgeries and permanent neurostimulator implants.

Household mold linked to inflammatory lung disease

 

Mold growth in homes is a significant trigger for hypersensitivity pneumonitis (HP), an inflammatory lung disease, according to a new study led by UT Southwestern Medical Center. Published in PLOS One, the research represents the largest study to date linking home mold exposure to HP and the first from North Texas.

Study links female sex hormones to progression of eye disease

 

Female sex hormones can significantly enhance the progression of the rare neurodegenerative eye disease retinitis pigmentosa (RP), according to a preclinical study by researchers at UT Southwestern Medical Center. The findings, published in Science Advances, may lead to therapeutics to slow progression of the disease and help clinicians assess the risk of hormone therapies for female patients with genetic markers for the disease.