2021 Article Archive

Sending out an SOS to protect the heart

 

A stress signal received by the heart from fat could help protect against cardiac damage induced by obesity, a new study led by UT Southwestern researchers suggests. The finding, published online in Cell Metabolism, could help explain the “obesity paradox,” a phenomenon in which obese individuals have better short- and medium-term cardiovascular disease prognoses compared with those who are lean, but with ultimately worse long-term outcomes.

UT Southwestern pioneers PULSAR-integrated radiotherapy with immunotherapy for improved tumor control

 

Artificial intelligence, along with a $71-million expansion of Radiation Oncology services, is allowing UT Southwestern Medical Center cancer physicians to pioneer a new PULSAR radiation-therapy strategy that improves tumor control compared with traditional daily therapy.

NEJM: Anticoagulants help moderately ill COVID-19 patients

 

Moderately ill patients hospitalized with COVID-19 have better chances of survival if treated with therapeutic-dose anticoagulation, according to an international study involving 121 sites, including UT Southwestern Medical Center.

A master gear in the circadian clock

 

A gene called Npas4, already known to play a key role in balancing excitatory and inhibitory inputs in brain cells, appears to also be a master timekeeper for the brain’s circadian clock, new research led by UT Southwestern scientists suggests.

Increasing the immune system’s appetite for cancer protectors

 

A two-arm molecule can effectively deplete cancer-protecting cells inside tumors, allowing the immune system to fight off tumors without becoming overactive.

Hunting down the mutations that cause cancer drug resistance

 

Using a virus to purposely mutate genes that produce cancer-driving proteins could shed light on the resistance that inevitably develops to cancer drugs that target them, a new study led by UT Southwestern scientists suggests.

UTSW physician volunteering at Tokyo Olympics

 

Dr. Stephanie Tow, M.D., completed her first week of providing volunteer care at the Tokyo 2020 Olympics.

Headaches are vastly undertreated among racial and socioeconomic groups

 

UTSW research finds significant disparities exist in diagnosing and treating headaches by race, socioeconomic level, and insurance status.

Common weight-loss drug successfully targets fat that can endanger heart health

 

Researchers at UT Southwestern announced successful results of a clinical trial for a commonly prescribed weight-loss drug called liraglutide.

Artificial intelligence algorithm developed to assess metastatic potential in skin cancers

 

Using artificial intelligence (AI), researchers from UT Southwestern have developed a way to accurately predict which skin cancers are highly metastatic.