The Division of Endocrinology at UT Southwestern encompasses all aspects of endocrinology. A variety of clinical and basic research efforts are directed by a diverse faculty whose expertise spans the spectrum of endocrine disease. Areas of particular strength include steroid hormone biosynthesis and metabolism, endocrine development, and reproduction.
INTEREST: How cells and tissues regulate intracellular lipid storage and utilization and its effects on systemic glucose and lipid metabolism.
INTEREST: Global diabetes program to improve the lives and health of people with diabetes through patient-centered evidence-based care, education, research, and community partnerships.
INTEREST: Advancing diagnosis and treatment of patients with pituitary, adrenal and neuroendocrine disorders through multidisciplinary patient-centered care, education, and research.
INTEREST: improving lives of diabetes and obesity patients through understanding of pathophysiology of disease and development of optimal treatment regimens.
INTEREST: chemical and genetic approaches to identify new targets for therapy for small cell lung cancer, thyroid cancer and pediatric sarcomas. The lab uses genetically-engineered mouse cancer models and human cancer cell lines as model systems.
Visit the McFadden Lab
INTEREST: distinguish endocrine changes during active lactation from delayed maternal metabolic reprogramming apparent after the end of lactation
INTEREST: endocrine regulation of arterial calcification — key contributor to stroke, heart failure, and lower extremity amputation risk in the settings of diabetes and uremia. Current research emphasizes the role LRP6 and arginine methylation cascades in arteriosclerotic Wnt signaling, Wnt production, and microvesicle metabolism. Endocrinology / Hypothalamic / Touchstone Diabetes.