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Recent Publications from AIRC Staff and Collaborators

  •  Simultaneous tracers and a unified model of positional and mass isotopomers for quantification of metabolic flux in liver. S Deja, X Fu, JA Fletcher, B Kucejova, JD Browning, JD Young, SC Burgess. Metab Eng. 2020 May;59:1-14. doi: 10.1016/j.ymben.2019.12.005. Epub (2019)

  •  Assessment of Rapid Hepatic Glycogen Synthesis in Humans Using Dynamic 13C Magnetic Resonance Spectroscopy. S Stender, VG Zaha, CR Malloy, J Sudderth, RJ DeBerardinis, & JM Park. Hepatol Commun. 2020 Jan 4;4(3):425-433. doi: 10.1002/hep4.1458. eCollection (2020 Mar.)

  •  Does Tumor FDG-PET Avidity Represent Enhanced Glycolytic Metabolism in Non-Small Cell Lung Cancer? KH Kernstine, B Faubert, QN Do, TJ Rogers, CT Hensley, L Cai, J Torrealba, D Oliver, JW Wachsmann, RE Lenkinski, CR Malloy, RJ Deberardinis. Ann Thorac Surg. 2020 Apr;109(4):1019-1025. doi: 10.1016/j.athoracsur.2019.10.061. Epub (2019)

  •  Advances in stable isotope tracer methodology part 1: hepatic metabolism via isotopomer analysis and postprandial lipolysis modeling. C Diniz Behn, ES Jin, K Bubar, CR Malloy, EJ Parks, M Cree-Green.  J Investig Med. 2020 Jan;68(1):3-10. doi: 10.1136/jim-2019-001109. Epub (2019)

  • Active pyruvate dehydrogenase and impaired gluconeogenesis in orthotopic hepatomas of rats. MH Lee, RJ DeBerardinis, X Wen, IR Corbin, AD Sherry, CR Malloy, ES Jin.  2019 Dec;101:153993. doi: 10.1016/j.metabol.2019.153993. Epub (2019) 

  •  Real-time hyperpolarized 13C magnetic resonance detects increased pyruvate oxidation in pyruvate dehydrogenase kinase 2/4-double knockout mouse livers. G Sharma, CY Wu, RM Wynn, w Gui, CR Malloy, AD Sherry, DT Chuang, C Khemtong. Sci Rep. 2019 Nov 11;9(1):16480. doi: 10.1038/s41598-019-52952-6. 

  •  MultimodalityHyperpolarized C-13 MRS/PET/Multiparametric MR Imaging for Detection and Image-Guided Biopsy of Prostate Cancer: First Experience in a Canine Prostate Cancer Model. SV Bachawal, JM Park, KS Valluru, MD Loft, SA Felt, JG Vilches-Moure, YF Saenz, B Daniel, A Iagaru, G Sonn, Z Cheng, DM Spielman, JK Willmann. Mol Imaging 2019 Oct;21(5):861-870. doi: 10.1007/s11307-018-1235-6. 

  •  Probing carbohydrate metabolism using hyperpolarized 13 C-labeled molecules.J Singh, EH Suh, G Sharma, C Khemtong, AD Sherry, Z Kovacs. NMR Biomed. 2019 Oct;32(10):e4018. doi: 10.1002/nbm.4018. Epub (2019) 

  •  Oxygen-sensitive MRI assessment of tumor response to hypoxic gas breathing challenge. DM Yang, TJ Arai, JW Campbell 3rd, JL Gerberich, H Zhou, & RP Mason.  NMR Biomed. 2019 Jul;32(7):e4101. doi: 10.1002/nbm.4101. Epub (2019)

  •  A simple method to monitor hepatic gluconeogenesis and triglyceride synthesis following oral sugar tolerance test in obese adolescents. AM Carreau, ES Jin, Y Garcia-Reyes, H Rahat, KJ Nadeau, CR Malloy, & M Cree-Green.  Am J Physiol Regul Integr Comp Physiol. 2019 Jul 1;317(1):R134-R142. doi: 10.1152/ajpregu.00047.2019. Epub (2019)

  • The effect of flow on blood oxygen level dependent (R*2 ) MRI of orthotopic lung tumors. H Zhou, O Belzile, Z Zhang, J Wagner, C Ahn, JA Richardson, D Saha, RA Brekken, & RP Mason. Magn Reson Med. 2019 Jun;81(6):3787-3797. doi: 10.1002/mrm.27661. Epub (2019)