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The NMF is supported in part by the Peter O/Donnell Brain Institute (OBI). Please remember to acknowledge your use of our facility resources in your publications by including “UT Southwestern Neuro-Models Facility; RRID: SCR_022529” in your methods or acknowledgements section. We welcome and appreciate acknowledgement or authorship of specific facility personnel as appropriate.

The following publications include services and data produced by the UT Southwestern Neuro-Models Facility.

Repetitive hypoxic preconditioning induces an immunosuppressed B cell phenotype during endogenous protection from stroke.
Monson NL, Ortega SB, Ireland SJ, Meeuwissen AJ, Chen D, Plautz EJ, Shubel E, Kong X, Li MK, Freriks LH, Stowe AM.
J Neuroinflammation. 2014 Jan 31;11:22. doi: 10.1186/1742-2094-11-22. PMID: 24485041

The role of ryanodine receptor type 3 in a mouse model of Alzheimer disease.
Liu J, Supnet C, Sun S, Zhang H, Good L, Popugaeva E, Bezprozvanny I. Channels (Austin). 2014;8(3):230-42. PMID: 24476841

Activity-dependent FUS dysregulation disrupts synaptic homeostasis.
Sephton CF, Tang AA, Kulkarni A, West J, Brooks M, Stubblefield JJ, Liu Y, Zhang MQ, Green CB, Huber KM, Huang EJ, Herz J, Yu G.
Proc Natl Acad Sci USA. 2014 Nov 4;111(44):E4769-78. doi: 10.1073/pnas.1406162111. Epub 2014 Oct 16. PMID: 25324524

Single dose of glycoengineered anti-CD19 antibody (MEDI551) disrupts experimental autoimmune encephalomyelitis by inhibiting pathogenic adaptive immune responses in the bone marrow and spinal cord while preserving peripheral regulatory mechanisms.
Chen D, Blazek M, Ireland S, Ortega S, Kong X, Meeuwissen A, Stowe A, Carter L, Wang Y, Herbst R, Monson NL.
J Immunol. 2014 Nov 15;193(10):4823-32. doi: 10.4049/jimmunol.1401478. Epub 2014 Oct 3. PMID: 25281717

Aberrant hippocampal neurogenesis contributes to epilepsy and associated cognitive decline.
Cho KO, Lybrand ZR, Ito N, Brulet R, Tafacory F, Zhang L, Good L, Ure K, Kernie SG, Birnbaum SG, Scharfman HE, Eisch AJ, Hsieh J.
Nat Commun. 2015 Mar 26;6:6606. doi: 10.1038/ncomms7606. PMID: 25808087

Quantification of neurovascular protection following repetitive hypoxic preconditioning and transient middle cerebral artery occlusion in mice.
Poinsatte K, Selvaraj UM, Ortega SB, Plautz EJ, Kong X, Gidday JM, Stowe AM.
J Vis Exp. 2015 May 4;(99):e52675. doi: 10.3791/52675. PMID: 25993394

Stroke induces a rapid adaptive autoimmune response to novel neuronal antigens.
Ortega SB, Noorbhai I, Poinsatte K, Kong X, Anderson A, Monson NL, Stowe AM.
Discov Med. 2015 May;19(106):381-92. PMID: 26105701

Origin of a Non-Clarke's Column Division of the Dorsal Spinocerebellar Tract and the Role of Caudal Proprioceptive Neurons in Motor Function.
Yuengert R, Hori K, Kibodeaux EE, McClellan JX, Morales JE, Huang TW, Neul JL, Lai HC.
Cell Rep. 2015 Nov 10;13(6):1258-71. doi: 10.1016/j.celrep.2015.09.064. Epub 2015 Oct 29. PMID: 26527010

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy.
Long C, Amoasii L, Mireault AA, McAnally JR, Li H, Sanchez-Ortiz E, Bhattacharyya S, Shelton JM, Bassel-Duby R, Olson EN.
Science. 2016 Jan 22;351(6271):400-3. doi: 10.1126/science.aad5725. Epub 2015 Dec 31. PMID: 26721683

An automated task for the training and assessment of distal forelimb function in a mouse model of ischemic stroke.
Becker AM, Meyers E, Sloan A, Rennaker R, Kilgard M, Goldberg MP.
J Neurosci Methods. 2016 Jan 30;258:16-23. doi: 10.1016/j.jneumeth.2015.10.004. Epub 2015 Oct 17. PMID: 26484787

Perinatal chronic hypoxia induces cortical inflammation, hypomyelination, and peripheral myelin-specific T cell autoreactivity.
Ortega SB, Kong X, Venkataraman R, Savedra AM, Kernie SG, Stowe AM, Raman L.
J Leukoc Biol. 2016 Jan;99(1):21-9. doi: 10.1189/jlb.5HI0914-447R. Epub 2015 Jun 2. PMID: 26038434

Autoreactive CD19+CD20- Plasma Cells Contribute to Disease Severity of Experimental Autoimmune Encephalomyelitis.
Chen D, Ireland SJ, Davis LS, Kong X, Stowe AM, Wang Y, White WI, Herbst R, Monson NL.
J Immunol. 2016 Feb 15;196(4):1541-9. doi: 10.4049/jimmunol.1501376. Epub 2016 Jan 13. PMID: 26764035

Preconditioning-induced CXCL12 upregulation minimizes leukocyte infiltration after stroke in ischemia-tolerant mice.
Selvaraj UM, Ortega SB, Hu R, Gilchrist R, Kong X, Partin A, Plautz EJ, Klein RS, Gidday JM, Stowe AM.
J Cereb Blood Flow Metab. 2016 Mar 22. pii: 0271678X16639327. PMID: 27006446

Physiologic Reelin does not play a strong role in protection against acute stroke.
Lane-Donovan C, Desai C, Pohlkamp T, Plautz EJ, Herz J, Stowe AM.
J Cereb Blood Flow Metab. 2016 Jul;36(7):1295-303. doi: 10.1177/0271678X16646386. Epub 2016 May 4. PMID: 27146512

Involvement of aberrant cyclin-dependent kinase 5/p25 activity in experimental traumatic brain injury.
Yousuf MA, Tan C, Torres-Altoro MI, Lu FM, Plautz E, Zhang S, Takahashi M, Hernandez A, Kernie SG, Plattner F, Bibb JA.
J Neurochem. 2016 Jul;138(2):317-27. doi: 10.1111/jnc.13620. Epub 2016 May 25. PMID: 26998748

Selective Nonnuclear Estrogen Receptor Activation Decreases Stroke Severity and Promotes Functional Recovery in Female Mice.
Selvaraj UM, Zuurbier KR, Whoolery CW, Plautz EJ, Chambliss KL, Kong X, Zhang S, Kim SH, Katzenellenbogen BS, Katzenellenbogen JA, Mineo C, Shaul PW, Stowe AM.
Endocrinology. 2018 Nov 1;159(11):3848-3859. doi: 10.1210/en.2018-00600. PMID: 30256928

Visualization and Quantification of Post-stroke Neural Connectivity and Neuroinflammation Using Serial Two-Photon Tomography in the Whole Mouse Brain.
Poinsatte K, Betz D, Torres VO, Ajay AD, Mirza S, Selvaraj UM, Plautz EJ, Kong X, Gokhale S, Meeks JP, Ramirez DMO, Goldberg MP, Stowe AM.
Front Neurosci. 2019 Oct 4;13:1055. doi: 10.3389/fnins.2019.01055. eCollection 2019. PMID: 31636534

Short-Chain Fatty Acids Improve Poststroke Recovery via Immunological Mechanisms.
Sadler R, Cramer JV, Heindl S, Kostidis S, Betz D, Zuurbier KR, Northoff BH, Heijink M, Goldberg MP, Plautz EJ, Roth S, Malik R, Dichgans M, Holdt LM, Benakis C, Giera M, Stowe AM, Liesz A.
J Neurosci. 2020 Jan 29;40(5):1162-1173. doi: 10.1523/JNEUROSCI.1359-19.2019. Epub 2019 Dec 30. PMID: 31889008

Impaired meningeal lymphatic vessel development worsens stroke outcome.
Yanev P, Poinsatte K, Hominick D, Khurana N, Zuurbier KR, Berndt M, Plautz EJ, Dellinger MT, Stowe AM.
J Cereb Blood Flow Metab. 2020 Feb;40(2):263-275. doi: 10.1177/0271678X18822921. Epub 2019 Jan 9. PMID: 30621519

B cells migrate into remote brain areas and support neurogenesis and functional recovery after focal stroke in mice.
Ortega SB, Torres VO, Latchney SE, Whoolery CW, Noorbhai IZ, Poinsatte K, Selvaraj UM, Benson MA, Meeuwissen AJM, Plautz EJ, Kong X, Ramirez DM, Ajay AD, Meeks JP, Goldberg MP, Monson NL, Eisch AJ, Stowe AM.
Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):4983-4993. doi: 10.1073/pnas.1913292117. Epub 2020 Feb 12. PMID: 32051245

Delayed diapedesis of CD8 T cells contributes to long-term pathology after ischemic stroke in male mice.
Selvaraj UM, Ujas TA, Kong X, Kumar A, Plautz EJ, Zhang S, Xing C, Sudduth TL, Wilcock DM, Turchan-Cholewo J, Goldberg MP, Stowe AM.
Brain Behav Immun. 2021 Jul;95:502-513. doi: 10.1016/j.bbi.2021.05.001. Epub 2021 May 5. PMID: 33964435

Increased glycine contributes to synaptic dysfunction and early mortality in Nprl2 seizure model.
Dentel B, Angeles-Perez L, Ren C, Jakkamsetti V, Holley AJ, Caballero D, Oh E, Gibson J, Pascual JM, Huber KM, Tu BP, Tsai PT.
iScience. 2022 Apr 29;25(5):104334. doi: 10.1016/j.isci.2022.104334. eCollection 2022 May 20. PMID: 35602938

A sound-driven cortical phase-locking change in the Fmr1 KO mouse requires Fmr1 deletion in a subpopulation of brainstem neurons.
Holley AJ, Shedd A, Boggs A, Lovelace J, Erickson C, Gross C, Jankovic M, Razak K, Huber K, Gibson JR.
Neurobiol Dis. 2022 May 17;170:105767. doi: 10.1016/j.nbd.2022.105767. Online ahead of print. PMID: 35588990