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New role for innate immune sensor: suppressing liver cancer: Newsroom, UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2019/suppressing-liver-cancer.html

UT Southwestern researchers have found that a protein in the body’s innate immune system that responds to gut microbes can suppress the most common type of liver cancer.

Preoperative immunotherapy could enhance breast cancer cure rates: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/feb-preoperative-immunotherapy.html

A phase three clinical trial co-led by a researcher at UT Southwestern Harold C. Simmons Comprehensive Cancer Center showcases the promise of administering immunotherapy along with chemotherapy before surgery in patients with breast cancer at high risk of spreading. The findings, published in Nature

Tips for tackling your diet at Super Bowl parties: Newsroom, UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2019/super-bowl-parties.html

If you have resolved to eat healthier to manage your diabetes, blood pressure, or cholesterol, parties can present a challenge, so it’s important to have a game plan before tackling the Super Bowl spread.

AI tool helps identify heart failure risk in diabetes patients: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/oct-diabetic-cardiomyopathy.html

Researchers at UT Southwestern Medical Center have developed a machine learning model that can identify patients with diabetic cardiomyopathy, a heart condition characterized by abnormal changes in the heart’s structure and function that predisposes them to increased risk of heart failure.

UT Southwestern expands neurosurgical program to Texas Health Dallas: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/neurosurgical-program.html

UT Southwestern Medical Center is expanding its neurological surgery program to Texas Health Presbyterian Hospital Dallas.

First structure of human cotransporter protein family member solved: Newsroom - UT Southwestern, Dallas, TX

https://www.utsouthwestern.edu/newsroom/articles/year-2019/cotransporter-protein.html

In work that could someday improve treatments for epilepsy, UT Southwestern scientists have published the first three-dimensional structure of a member of a large family of human proteins that carry charged particles – ions – across the cell membrane.

Researchers show how mutations in DNA packaging machines cause cancer: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/dna-mutations-cancer.html

Like wrenches made of Legos, SWI/SNF chromatin remodeling complexes tighten or loosen DNA in our cells to control how genes are turned on and made into proteins.

Screening approach helps identify sources of rare genetic diseases in children: Newsroom, UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2019/new-screening-approach.html

The new approach combines DNA sequencing and a chemical analysis called metabolomics to identify mutant genes that cause defective metabolic pathways in patients.

Why the dose matters: Study shows that levels of drug in body correlate to ability to shrink tumors: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2020/why-the-dose-matters.html

When used to manage infections, the drug itraconazole is generally given at a single, fixed dose to all patients.

Newly identified bacteria-killing protein needs vitamin A to work: Newsroom, UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2019/bacteria-killing-protein.html

UT Southwestern researchers identified a previously unknown bacteria-killing protein on the epidermis that requires the vitamin to work.