Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern researchers reported.

A new study by UT Southwestern’s Simmons Cancer Center scientists suggests that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that fight cancer.

For the third year in a row, UT Southwestern is ranked as the top health care institution globally by Nature Index for publishing high-quality research in all subjects and in the life sciences.

An enzyme called Fic, whose biochemical role was discovered at UT Southwestern more than a dozen years ago, appears to play a crucial part in guiding the cellular response to stress, a new study suggests.

Low-income seniors were seven times more likely to visit a food pantry in the year after becoming eligible for Medicare, resulting in improved food security, according to a new study from UT Southwestern.

Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA’s regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to two recent studies in Nature Genetics.

UT Southwestern is joining with medical centers around the nation to apply advanced sequencing to pediatric brain tumors as part of the National Cancer Institute’s new Molecular Characterization Initiative, a subset of the Cancer Moonshot Childhood Cancer Initiative.

Swallowing fluoroscopy is the most common diagnostic test for patients with swallowing problems caused by conditions such as stroke, head and neck cancer, neurodegenerative disease, or prolonged intubation.

The dominant form of heart failure worldwide appears to be caused by a strong, bidirectional interaction between the body’s response to metabolic stress and the immune system, according to a review article written by UT Southwestern researchers and colleagues.

More teenage athletes experienced depression and anxiety during the early weeks of the pandemic, when COVID-19 restrictions curtailed sports activities, according to a survey of 600 child and adolescent athletes led by researchers at UT Southwestern and Scottish Rite for Children.