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Metabolite Profiling If a particular chemical series shows poor metabolic stability, knowledge of the specific metabolites formed can aid chemists in the design of more stable analogues. A comparison of the metabolites formed in different species can also aid in the selection of appropriate species f…

Routine Histology The Histo Pathology Core offers routine histology services for workup of specimens as paraffin or frozen. Routine histology services offered include: Paraffin Processing and Embedding: Automated, Manual, Chromagen Cryoembedding: TFM, OCT, or Gum Tragacanth Paraffin Sectioning: H&Es …

Co-IP Experiments Introduction One of the most common types of experiment submitted for analysis in the Proteomics Core is the Co-IP experiment. An antibody against endogenous or tagged protein is used to pull down a protein of interest. The goal of the experiment is to see what comes down with that …

Charging Policy What is our policy for charging users? The Proteomics Core has a simple charging policy: No samples will be prepared or run until the information has been entered into our sample submission site. We charge for every sample run , regardless of whether an expected result is obtained. Th…

The UTSW University Police Department offers other services such as assistance with disabled vehicles, fingerprinting, lost and found, and personal escorts.

Learn about the job duties and requirements for a Police Communication Operator with the UT Southwestern Medical Police Department.

Cutting Gels Introduction Many proteomics samples are well suited for SDS-PAGE, including protein identification and PTM identification. We recognize that a gel approach may not be compatible with all samples, so please contact us if you have concerns about running your sample into a gel. We require …

TMT Quantitation Introduction Tandem Mass Tag (TMT) technology is a powerful technique for comparing protein (and peptide) amounts between six to eighteen conditions. This technique involves labeling samples after digestion, meaning this technique can be used on in vivo samples, unlike SILAC. TMT or …

Complex Mixture ID Introduction Modern LC-MS/MS platforms can identify several thousands of proteins from a single sample. We realize that many different types of samples can be submitted for proteomics analsyis, so we accept a wide range of sample formats, including: On-bead (magnetic beads preferre…

Learn more about the job duties and requirements for a Cadet/Police Officer with the UT Southwestern Medical Center Police Department.